Biochemistry and Molecular Biology

BIOCHEMISTRY AND MOLECULAR BIOLOGY (HONOURS)

The Bachelor of Advanced Studies (Honours) (Biochemistry and Molecular Biology) requires 48 credit points from this table including:
(i) 6 credit points of 4000-level Honours coursework core units, and
(ii) 6 credit points of 4000-level Honours coursework selective units, and
(iii) 36 credit points of 4000-level Honours research project units

Honours Coursework Core

LIFE4101 Advanced Life Science

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: A WAM of 65 or greater. 144 credit points of units of study, including a minimum of 12 credit points from the following (AMED3XXX or ANAT3XXX or ANSC3105 or BCHM3XXX or BCMB3XXX or BIOL3XXX or CPAT3XXX or ENVX3XXX or FOOD3XXX or GEGE3XXX or HSTO3XXX or IMMU3XXX or INFD3XXX or MEDS3XXX or MICR3XXX or NEUR3XXX or NUTM3XXX or PCOL3XXX or PHSI3XXX or QBIO3XXX or SCPU3001 or STAT3XXX or VIRO3XXX) Assumed knowledge: This unit is advanced coursework related to understanding cellular and molecular processes in biology. It assumes background knowledge of cellular and molecular biological aspects of the life sciences consistent with a degree major in Biochemistry, Biochemistry and Molecular Biology, Cell and Developmental Biology, Cell Pathology, Genetics and Genomics, Immunobiology, Infectious Diseases, Medical Science, Microbiology, Molecular Biology and Genetics, Nutrition and Metabolism, Nutrition Science, or Quantitative Life Sciences Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Department permission required for enrolment
Note: This unit must be taken by all students in Biochemistry and Molecular Biology honours or Microbiology honours.
Living organisms are impacted by processes that occur across a very wide range of scales. These range from rapid processes at the molecular and cellular scale to multi-year processes at environmental and evolutionary scales. One of the great challenges for modern systems biology is integrating measurements across these scales to understand gene x environment interactions. This unit will develop your skills in this area through critical analysis of a series of recent research papers on a themed topic in small group discussions. For each paper we will explore principles behind the key methods and the methods' practicality. We will look at how those methods were incorporated into an experimental design to address a biological question. We will critically assess the support for conclusions in their paper and their scientific significance. By doing this unit you will develop skills in reading and interpreting primary scientific literature and an advanced understanding of the modern topic in systems biology. You will gain a high level of understanding of the theory of key biochemical and statistical methods for analysis of genes, proteins, and cells in biological systems. You will gain the confidence to apply these insights to planning, conducting and reporting your own research findings.

Honours Coursework Selective

LIFE4000 Data and Technology for the Life Sciences

Credit points: 6 Session: Semester 1a Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: 144 credit points of units of study including a minimum of 24 credit points at the 3000- or 4000-level and 18 credit points of 3000- or 4000-level units from Science Table A or 1 Assumed knowledge: Completion of units in quantitative research methods, mathematics or statistical analysis at least at 1000-level Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Campus: Camperdown/Darlington, Sydney Mode of delivery: Block mode
Advances in digital technology are creating new ways to quantify biological processes and properties, from the scale of molecules to ecosystems. The life scientist of the 21st century needs to understand how to collect, manage, synthesise, and communicate this information within a reproducible workflow in order to make robust inferences about the natural world. This intensive unit of study will introduce you to key concepts and tools across three modules: digital project and data management, evidence synthesis and meta-analysis, and scientific coding using R. The focus is on active learning, discussion, and problem-solving across intensive workshop-based practicals, rather than the traditional lecture format. By completing this unit you will further understand the practical realities of scientific inquiry. To that end, you will develop a flexible skillet for conducting reproducible and open research to ensure the results of your work are maximally beneficial to both your future self and the broader community. Knowledge of how to work with data through the entire pipeline -from sampling to synthesis-will be useful wherever it is encountered in your education, career, and life.
Textbooks
Refer to the unit of study outline https://www.sydney.edu.au/units
SCIE4001 Science Communication

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: 144 credit points of units of study and including a minimum of 24 credit points at the 3000- or 4000-level and 18 credit points of 3000- or 4000-level units from Science Table A Assumed knowledge: Completion of a major in a science discipline. Basic knowledge of other sciences is beneficial. Experience in communication such as delivering oral presentations and producing written reports. An awareness of science in a societal context, e.g., of disciplinary applications Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Mid-year honours students would take this unit of study in S1 (their second semester of study).
"If you can't explain it simply, you don't understand it well enough". This quote is widely attributed to Albert Einstein, but regardless of its provenance, it suggests that one measure of an expert's knowledge can be found in their ability to translate complex ideas so that they are accessible to anyone. The communication of science to the public is essential for science and society. In order to increase public understanding and appreciation of science, researchers must be able to explain their results, and the wider context of their research, to non-experts. This unit will explore some theoretical foundations of science communications, identify outstanding practitioners and empower students to produce effective science communication in different media. In this unit you will learn the necessary skills and techniques to tell engaging and informative science stories in order to bring complex ideas to life, for non-expert audiences. By undertaking this unit you will develop a greater understanding of the wider context of your honours unit, advance your communication skills and be able to explain your honours research to non-expert audiences such as friends, family or future employers. These transferable skills will equip you for future research - where emphasis is increasingly placed on public communication and/or outreach - or professional pathways - where effective communication of complex ideas is highly valued.
SCIE4002 Experimental Design and Data Analysis

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1a Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: 144 credit points of units of study and including a minimum of 24 credit points at the 3000- or 4000-level and 18 credit points of 3000- or 4000-level units from Science Table A Prohibitions: ENVX3002 or STAT3X22 or STAT4022 or STAT3X12 Assumed knowledge: Completion of units in quantitative research methods, mathematics or statistical analysis at least at 1000-level Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Campus: Camperdown/Darlington, Sydney Mode of delivery: Block mode
An indispensable attribute of an effective scientific researcher is the ability to collect, analyse and interpret data. Central to this process is the ability to create hypotheses and test these by using rigorous experimental designs. This modular unit of study will introduce the key concepts of experimental design and data analysis. Specifically, you will learn to formulate experimental aims to test a specific hypothesis. You will develop the skills and understanding required to design a rigorous scientific experiment, including an understanding of concepts such as controls, replicates, sample size, dependent and independent variables and good research practice (e.g. blinding, randomisation). By completing this unit you will develop the knowledge and skills required to appropriately analyse and interpret data in order to draw conclusions in the context of an advanced research project. From this unit of study, you will emerge with a comprehensive understanding of how to optimise the design and analysis of an experiment to most effectively answer scientific questions.
SCIE4003 Ethics in Science

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1a,Semester 2a Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: 144 credit points of units of study and including a minimum of 24 credit points at the 3000- or 4000-level and 18 credit points of 3000- or 4000-level units from Science Table A Prohibitions: HSBH3004 or HPSC3107 Assumed knowledge: Successful completion of a Science major Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: Completion of ITAR Modules required for students who choose the Animal Ethics module. Campus: Camperdown/Darlington, Sydney Mode of delivery: Block mode
In the contemporary world, a wide variety of ethical concerns impinge upon the practice of scientific research. In this unit, you will learn how to identify potential ethical issues within science, acquire the tools necessary to analyse them, and develop the ability to articulate ethically sound insights about how to resolve them. In the first portion of the unit, you will be familiarised with how significant developments in post-World War II science motivated sustained ethical debate among scientists and in society. In the second portion of the unit, you will select from either a Human Ethics module or an Animal Ethics module and learn the requirements of how to ensure your research complies with appropriate national legislation and codes of conduct. By undertaking this unit, you will develop the ability to conduct scientific research in an ethically justifiable way, place scientific developments and their application in a broader social context, and analyse the social implications and ethical issues that may potentially arise in the course of developing scientific knowledge.

Honours Core Research Project

BCMB4103 Biochemistry Honours Project A

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1,Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: Honours in Biochemistry rarely involves field work. If a project requires this, specific arrangements pertinent to that student/project will be put in place. Campus: Camperdown/Darlington, Sydney Mode of delivery: Supervision
Independent research can be a life changing experience. In this unit you will complete a research project in the discipline of Biochemistry. Together with your supervisor, you will identify a novel research question and develop a hypothesis. You will then design and carry out experiments to test your hypothesis. In terms of assessment, you will communicate the research plan and findings through written tasks and oral presentations culminating in a 10,000 word honours thesis. Successful completion of your Honours will clearly demonstrate that you have mastered significant research and professional skills for either undertaking a PhD or any variety of future careers.
BCMB4104 Biochemistry Honours Project B

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1,Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Corequisites: BCMB4103 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: Honours in Biochemistry rarely involves field work. If a project requires this, specific arrangements pertinent to that student/project will be put in place. Campus: Camperdown/Darlington, Sydney Mode of delivery: Supervision
Independent research can be a life changing experience. In this unit you will complete a research project in the discipline of Biochemistry. Together with your supervisor, you will identify a novel research question and develop a hypothesis. You will then design and carry out experiments to test your hypothesis. In terms of assessment, you will communicate the research plan and findings through written tasks and oral presentations culminating in a 10,000 word honours thesis. Successful completion of your Honours will clearly demonstrate that you have mastered significant research and professional skills for either undertaking a PhD or any variety of future careers.
BCMB4105 Biochemistry Honours Project C

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1,Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Corequisites: BCMB4104 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: Honours in Biochemistry rarely involves field work. If a project requires this, specific arrangements pertinent to that student/project will be put in place. Campus: Camperdown/Darlington, Sydney Mode of delivery: Supervision
Independent research can be a life changing experience. In this unit you will complete a research project in the discipline of Biochemistry. Together with your supervisor, you will identify a novel research question and develop a hypothesis. You will then design and carry out experiments to test your hypothesis. In terms of assessment, you will communicate the research plan and findings through written tasks and oral presentations culminating in a 10,000 word honours thesis. Successful completion of your Honours will clearly demonstrate that you have mastered significant research and professional skills for either undertaking a PhD or any variety of future careers.
BCMB4106 Biochemistry Honours Project D

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1,Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Corequisites: BCMB4105 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: Honours in Biochemistry rarely involves field work. If a project requires this, specific arrangements pertinent to that student/project will be put in place. Campus: Camperdown/Darlington, Sydney Mode of delivery: Supervision
Independent research can be a life changing experience. In this unit you will complete a research project in the discipline of Biochemistry. Together with your supervisor, you will identify a novel research question and develop a hypothesis. You will then design and carry out experiments to test your hypothesis. In terms of assessment, you will communicate the research plan and findings through written tasks and oral presentations culminating in a 10,000 word honours thesis. Successful completion of your Honours will clearly demonstrate that you have mastered significant research and professional skills for either undertaking a PhD or any variety of future careers.
BCMB4107 Biochemistry Honours Project E

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1,Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Corequisites: BCMB4106 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: Honours in Biochemistry rarely involves field work. If a project requires this, specific arrangements pertinent to that student/project will be put in place. Campus: Camperdown/Darlington, Sydney Mode of delivery: Supervision
Independent research can be a life changing experience. In this unit you will complete a research project in the discipline of Biochemistry. Together with your supervisor, you will identify a novel research question and develop a hypothesis. You will then design and carry out experiments to test your hypothesis. In terms of assessment, you will communicate the research plan and findings through written tasks and oral presentations culminating in a 10,000 word honours thesis. Successful completion of your Honours will clearly demonstrate that you have mastered significant research and professional skills for either undertaking a PhD or any variety of future careers.
BCMB4108 Biochemistry Honours Project F

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1,Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Corequisites: BCMB4107 and SCIE4999 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: Honours in Biochemistry rarely involves field work. If a project requires this, specific arrangements pertinent to that student/project will be put in place. Campus: Camperdown/Darlington, Sydney Mode of delivery: Supervision
Independent research can be a life changing experience. In this unit you will complete a research project in the discipline of Biochemistry. Together with your supervisor, you will identify a novel research question and develop a hypothesis. You will then design and carry out experiments to test your hypothesis. In terms of assessment, you will communicate the research plan and findings through written tasks and oral presentations culminating in a 10,000 word honours thesis. Successful completion of your Honours will clearly demonstrate that you have mastered significant research and professional skills for either undertaking a PhD or any variety of future careers.
SCIE4999 Final Honours Mark

Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1,Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
All students in Science Honours must enrol in this non-assessable unit of study in their final semester. This unit will contain your final Honours mark as calculated from your coursework and research project units.