University of Sydney Handbooks - 2020 Archive

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Infectious Diseases Descriptions

INFECTIOUS DISEASES

Infectious Diseases major

A major in Infectious Diseases requires 48 credit points from this table including:
(i) 6 credit points of 1000-level core units
(ii) 6 credit points of 1000-level selective units
(iii) 12 credit points of 2000-level core units according to the following:
(a) 6 credit points of 2000-level MIMI coded units or
(b) 6 credit points of 2000-level MEDS coded units for students in the Medical Science stream
(iv) 6 credit points of 2000-level selective units
(v) 6 credit points of 3000-level core units
(vi) 12 credit points of 3000-level selective units
(vii) 6 credit points of 3000-level interdisciplinary project units

Infectious Diseases minor

A minor in Infectious Diseases requires 36 credit points from this table including:
(i) 6 credit points of 1000-level core units
(ii) 6 credit points of 1000-level selective units
(iii) 12 credit points of 2000-level core units according to the following:
(a) 6 credit points of 2000-level MIMI coded units or
(b) 6 credit points of 2000-level MEDS coded units for students in the Medical Science stream
(iv) 6 credit points of 2000-level selective units
(v) 12 credit points of 3000-level core units
* The [[/handbooks/science/subject_areas_nz/virology_table.shtml||Virology minor]] also articulates to the Infectious Diseases major

Units of study

The units of study are listed below.

1000-level units of study

Core
BIOL1007 From Molecules to Ecosystems

Credit points: 6 Teacher/Coordinator: Dr Osu Lilje Session: Semester 2 Classes: 2-3 lectures per week and online material and 12 x 3-hour practicals Prohibitions: BIOL1907 or BIOL1997 Assumed knowledge: HSC Biology. Students who have not completed HSC Biology (or equivalent) are strongly advised to take the Biology Bridging Course (offered in February). Assessment: quizzes (15%), communication assessments (35%), proficiency assessment (10%), final exam (40%) Mode of delivery: Normal (lecture/lab/tutorial) day
Paradigm shifts in biology have changed the emphasis from single biomolecule studies to complex systems of biomolecules, cells and their interrelationships in ecosystems of life. Such an integrated understanding of cells, biomolecules and ecosystems is key to innovations in biology. Life relies on organisation, communication, responsiveness and regulation at every level. Understanding biological mechanisms, improving human health and addressing the impact of human activity are the great challenges of the 21st century. This unit will investigate life at levels ranging from cells, and biomolecule ecosystems, through to complex natural and human ecosystems. You will explore the importance of homeostasis in health and the triggers that lead to disease and death. You will learn the methods of cellular, biomolecular, microbial and ecological investigation that allow us to understand life and discover how expanding tools have improved our capacity to manage and intervene in ecosystems for our own health and organisms in the environment that surround and support us . You will participate in inquiry-led practicals that reinforce the concepts in the unit. By doing this unit you will develop knowledge and skills that will enable you to play a role in finding global solutions that will impact our lives.
Textbooks
Please see unit outline on LMS
BIOL1907 From Molecules to Ecosystems (Advanced)

Credit points: 6 Teacher/Coordinator: Dr Claudia Keitel Session: Semester 2 Classes: 2-3 lectures per week and online material and 12 x 3-hour practicals Prohibitions: BIOL1007 or BIOL1997 Assumed knowledge: 85 or above in HSC Biology or equivalent Assessment: quizzes (14%), communication assessments (36%), proficiency assessment (10%), final exam (40%) Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Department permission required for enrolment
Paradigm shifts in biology have changed the emphasis from single biomolecule studies to complex systems of biomolecules, cells and their interrelationships in ecosystems of life. Such an integrated understanding of cells, biomolecules and ecosystems is key to innovations in biology. Life relies on organisation, communication, responsiveness and regulation at every level. Understanding biological mechanisms, improving human health and addressing the impact of human activity are the great challenges of the 21st century. This unit will investigate life at levels ranging from cells, and biomolecule ecosystems, through to complex natural and human ecosystems. You will explore the importance of homeostasis in health and the triggers that lead to disease and death. You will learn the methods of cellular, biomolecular, microbial and ecological investigation that allow us to understand life and discover how expanding tools have improved our capacity to manage and intervene in ecosystems for our own health and organisms in the environment that surround and support us . This unit of study has the same overall structure as BIOL1007 but material is discussed in greater detail and at a more advanced level. The content and nature of these components may vary from year to year.
Textbooks
Please see unit outline on LMS
BIOL1997 From Molecules to Ecosystems (SSP)

Credit points: 6 Teacher/Coordinator: Dr Emma Thompson Session: Semester 2 Classes: 2-3 lectures per week; online material; and 12 x 3-hour practicals Prohibitions: BIOL1007 or BIOL1907 Assumed knowledge: 90 or above in HSC Biology or equivalent Assessment: One 2-hour exam (40%), project report which includes written report and presentation (60%) Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Department permission required for enrolment
Paradigm shifts in biology have changed the emphasis from single biomolecule studies to complex systems of biomolecules, cells and their interrelationships in ecosystems of life. Such an integrated understanding of cells, biomolecules and ecosystems is key to innovations in biology. Life relies on organisation, communication, responsiveness and regulation at every level. Understanding biological mechanisms, improving human health and addressing the impact of human activity are the great challenges of the 21st century. This unit will investigate life at levels ranging from cells, and biomolecule ecosystems, through to complex natural and human ecosystems. You will explore the importance of homeostasis in health and the triggers that lead to disease and death. You will learn the methods of cellular, biomolecular, microbial and ecological investigation that allow us to understand life and intervene in ecosystems to improve health. The same theory will be covered as in the advanced stream but in this Special Studies Unit, the practical component is a research project. The research will be a synthetic biology project investigating genetically engineered organisms. Students will have the opportunity to develop higher level generic skills in computing, communication, critical analysis, problem solving, data analysis and experimental design.
Textbooks
Please see unit outline on LMS
Selective
BIOL1008 Human Biology

Credit points: 6 Teacher/Coordinator: Dr Hong Dao Nguyen Session: Semester 1 Classes: This unit of study will involve between 5-6 hours of face-to-face activities run on the Camperdown campus. These contact hours will comprise 2-3 hours of lectures per week; six 3 hour practical sessions; six 3 hour workshops/tutorials Prohibitions: BIOL1003 or BIOL1903 or BIOL1993 or MEDS1001 or MEDS1901 or BIOL1908 or BIOL1998 Assumed knowledge: HSC Biology. Students who have not completed HSC Biology (or equivalent) are strongly advised to take the Biology Bridging Course (offered in February). Assessment: post-module quizzes (10%), Living Data (25%), scientific report (20%), skills test (5%), final exam (40%) Practical field work: Six 3 hour lab classes Mode of delivery: Normal (lecture/lab/tutorial) day
What will it mean to be human in 2100? How will we be able to control our complex bodily mechanisms to maintain health and fight disease? Advances in the human biology suggest we will age more slowly and new technologies will enhance many bodily structures and functions. This unit of study will explore maintenance of health through nutritional balance, aerobic health, defence mechanisms and human diversity. You will learn key structural features from the subcellular level to the whole organ and body, and learn about essential functional pathways that determine how the body regulates its internal environment and responds to external stimuli and disease. Together we will investigate nutrition, digestion and absorption, cardiovascular and lung function, reproduction, development, epigenetics, and regulation of function through various interventions. You will receive lectures from experts in the field of human biology and medical sciences, supported by practical classes, workshops and on-line resources that leverage off state-of-the-art technologies to develop your practical, critical thinking, communication, collaboration, digital literacy, problem solving, and enquiry-based skills in human biology. This unit of study will provide you with the breadth and depth of knowledge and skills for further studies in majors in medical sciences.
Textbooks
Van Putte, C., Regan, J. and Russo, A. (*) Essentials of Anatomy and Physiology, McGraw Hill.
BIOL1908 Human Biology (Advanced)

Credit points: 6 Teacher/Coordinator: Dr Hong Dao Nguyen Session: Semester 1 Classes: This unit of study will involve between 5-6 hours of face-to-face activities run on the Camperdown campus. These contact hours will comprise 2-3 hours of lectures per week; six 3-hour practical sessions; six 3-hour workshops/tutorials Prohibitions: BIOL1003 or BIOL1903 or BIOL1993 or MEDS1001 or MEDS1901 or BIOL1008 or BIOL1998 Assumed knowledge: 85 or above in HSC Biology or equivalent Assessment: post-module quizzes (10%), Living Data (25%), scientific report (20%), skills test (5%), final exam (40%) Practical field work: Six 3 hour practicals Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Department permission required for enrolment
What will it mean to be human in 2100? How will we be able to control our complex bodily mechanisms to maintain health and fight disease? Advances in the human biology suggest we will age more slowly and new technologies will enhance many bodily structures and functions. This unit of study will explore maintenance of health through nutritional balance, aerobic health, defence mechanisms and human diversity. You will learn key structural features from the subcellular level to the whole organ and body, and learn about essential functional pathways that determine how the body regulates its internal environment and responds to external stimuli and disease. Together we will investigate nutrition, digestion and absorption, cardiovascular and lung function, reproduction, development, epigenetics, and regulation of function through various interventions. You will receive lectures from experts in the field of human biology and medical sciences, supported by practical classes, workshops and on-line resources that leverage off state-of-the-art technologies to develop your practical, critical thinking, communication, collaboration, digital literacy, problem solving, and enquiry-based skills in human biology. This unit of study will provide you with the breadth and depth of knowledge and skills for further studies in majors in medical sciences. The advanced unit has the same overall concepts as the mainstream unit but material is discussed in a manner that offers a greater level of challenge and academic rigour. Students enrolled in the advanced stream will participate in alternative components which may for example include guest lecturers from medical science industries. The nature of these components may vary from year to year.
Textbooks
Van Putte, C., Regan, J. and Russo, A. (*) Essentials of Anatomy and Physiology, McGraw Hill.
BIOL1998 Human Biology (Special Studies Program)

Credit points: 6 Teacher/Coordinator: Dr Rosalyn Gloag Session: Semester 1 Classes: Lectures as per BIOL1908; one 3-hour practical per week Prohibitions: BIOL1003 or BIOL1903 or BIOL1993 or BIOL1991 or BIOL1996 or MEDS1001 or MEDS1901 or BIOL1008 or BIOL1908 Assumed knowledge: 90 or above in HSC Biology or equivalent Assessment: One 2-hour exam (50%), practical report (25%), practical presentation (15%), lab note book (5%), pre laboratory quizzes (5%) Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Department permission required for enrolment
What will it mean to be human in 2100? How will we be able to control our complex bodily mechanisms to maintain health and fight disease? Advances in human biology suggest we will age more slowly and new technologies will enhance many bodily structures and functions. This unit of study will explore maintenance of health through nutritional balance, aerobic health, defence mechanisms and human diversity. You will learn key structural features from the subcellular level to the whole organ and body, and learn about essential functional pathways that determine how the body regulates its internal environment and responds to external stimuli and disease. Together we will investigate nutrition, digestion and absorption, cardiovascular and lung function, reproduction, development, epigenetics, and regulation of function through various interventions. You will receive lectures from experts in the field of human biology and medical sciences, supported by practical classes, workshops and on-line resources that leverage off state-of-the-art technologies to develop your practical, critical thinking, communication, collaboration, digital literacy, problem solving, and enquiry-based skills in human biology. This unit of study will provide you with the breadth and depth of knowledge and skills for further studies in majors in medical sciences. The practical work syllabus consists of a special project-based laboratory.
Textbooks
Van Putte, C., Regan, J. and Russo, A. (*) Essentials of Anatomy and Physiology, McGraw Hill.
CHEM1011 Fundamentals of Chemistry 1A

Credit points: 6 Teacher/Coordinator: Dr Toby Hudson Session: Semester 1 Classes: 3x1-hr lectures; 1x1-hr tutorial per week; 1x3-hr practical per week for 9 weeks Prohibitions: CHEM1001 or CHEM1101 or CHEM1901 or CHEM1903 or CHEM1109 or CHEM1111 or CHEM1911 or CHEM1991 Assumed knowledge: There is no assumed knowledge of chemistry for this unit of study but students who have not completed HSC Chemistry (or equivalent) are strongly advised to take the Chemistry Bridging Course (offered in February). Assessment: quizzes, attendance, laboratory log book, exam Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Students who have not completed HSC Chemistry (or equivalent) are strongly advised to take the Chemistry Bridging Course (offered in February, and online year-round, see https://sydney.edu.au/students/bridging-courses.html).
Chemistry describes how and why things happen from a molecular perspective. Chemistry underpins all aspects of the natural and physical world, and provides the basis for new technologies and advances in the life, medical and physical sciences, engineering, and industrial processes. This unit of study will equip you with the fundamental knowledge and skills in chemistry for broad application. You will learn about atomic theory, structure and bonding, equilibrium, processes occurring in solutions, and the functional groups of molecules. You will develop experimental design, conduct and analysis skills in chemistry through experiments that ask and answer questions about the chemical nature and processes occurring around you. Through inquiry, observation and measurement, you will better understand natural and physical world and will be able to apply this understanding to real-world problems and solutions. This unit of study is directed toward students whose chemical background is weak (or non-existent). Compared to the mainstream Chemistry 1A, the theory component of this unit begins with more fundamental concepts, and does not cover, or goes into less detail about some topics. Progression to intermediate chemistry from this unit and Fundamentals of Chemistry 1B requires completion of an online supplementary course.
Textbooks
Recommended textbook: Blackman, Bottle, Schmid, Mocerino and Wille,Chemistry, 3rd Edition, 2015 (John Wiley) ISBN: 978-0-7303-1105-8 (paperback) or 978-0-7303-2492-8 (e-text)
CHEM1111 Chemistry 1A

Credit points: 6 Teacher/Coordinator: Dr Toby Hudson Session: Intensive January,Semester 1,Semester 2 Classes: 3x1-hr lectures; 1x1-hr tutorial per week; 1x3-hr practical per week for 9 weeks Prohibitions: CHEM1001 or CHEM1101 or CHEM1901 or CHEM1903 or CHEM1109 or CHEM1011 or CHEM1911 or CHEM1991 Assumed knowledge: Students who have not completed HSC Chemistry (or equivalent) and HSC Mathematics (or equivalent) are strongly advised to take the Chemistry and Mathematics Bridging Courses (offered in February) Assessment: quizzes, attendance, laboratory log book, exam Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Students who have not completed secondary school chemistry are strongly advised to instead complete Fundamentals of Chemistry 1A in the first semester of the calendar year (unless you require 12 credit points of Chemistry and are commencing in semester 2). You should also take the Chemistry Bridging Course in advance (offered in February, and online year-round https://sydney.edu.au/students/bridging-courses.html).
Chemistry describes how and why things happen from a molecular perspective. Chemistry underpins all aspects of the natural and physical world, and provides the basis for new technologies and advances in the life, medical and physical sciences, engineering, and industrial processes. This unit of study will further develop your knowledge and skills in chemistry for application to life and medical sciences, engineering, and further study in chemistry. You will learn about nuclear and radiation chemistry, wave theory, atomic orbitals, spectroscopy, bonding, enthalpy and entropy, equilibrium, processes occurring in solutions, and the functional groups in carbon chemistry. You will develop experimental design, conduct and analysis skills in chemistry through experiments that ask and answer questions like how do dyes work, how do we desalinate water, how do we measure the acid content in foods, how do we get the blue in a blueprint, and how do we extract natural products from plants? Through inquiry, observation and measurement, you will understand the 'why' and the 'how' of the natural and physical world and will be able to apply this understanding to real-world problems and solutions. This unit of study is directed toward students with a satisfactory prior knowledge of the HSC chemistry course.
Textbooks
Recommended textbook: Blackman, Bottle, Schmid, Mocerino and Wille,Chemistry, 3rd Edition, 2015 (John Wiley) ISBN: 978-0-7303-1105-8 (paperback) or 978-0-7303-2492-8 (e-text)
CHEM1911 Chemistry 1A (Advanced)

Credit points: 6 Teacher/Coordinator: Dr Toby Hudson Session: Semester 1 Classes: 3x1-hr lectures and 1x1-hr tutorial per week; 1x3-hr practical per week for 9 weeks Prohibitions: CHEM1001 or CHEM1101 or CHEM1901 or CHEM1903 or CHEM1109 or CHEM1011 or CHEM1111 or CHEM1991 Assumed knowledge: 80 or above in HSC Chemistry or equivalent Assessment: quizzes, attendance, laboratory log book, exam Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Department permission required for enrolment
Chemistry describes how and why things happen from a molecular perspective. Chemistry underpins all aspects of the natural and physical world, and provides the basis for new technologies and advances in sciences, engineering, and industrial processes. This unit of study will further develop your knowledge and skills in chemistry for broad application, including further study in chemistry. You will learn about nuclear and radiation chemistry, wave theory, atomic orbitals, spectroscopy, bonding, enthalpy and entropy, equilibrium, processes occurring in solutions, and the functional groups of molecules. You will develop experimental design, conduct and analysis skills in chemistry through experiments that ask and answer questions about the chemical nature and processes occurring around you. Through inquiry, observation and measurement, you will better understand natural and physical world and will be able to apply this understanding to real-world problems and solutions. This unit of study is directed toward students with a good secondary performance both overall and in chemistry or science. Students in this category are expected to do this unit rather than Chemistry 1A. Compared to the mainstream Chemistry 1A, the theory component of this unit provides a higher level of academic rigour and makes broader connections between topics.
Textbooks
Recommended textbook: Blackman, Bottle, Schmid, Mocerino and Wille,Chemistry, 3rd Edition, 2015 (John Wiley) ISBN: 978-0-7303-1105-8 (paperback) or 978-0-7303-2492-8 (e-text)
CHEM1991 Chemistry 1A (Special Studies Program)

Credit points: 6 Teacher/Coordinator: Dr Toby Hudson Session: Semester 1 Classes: 3x1-hr lectures; 1x1-hr tutorial per week; 1x3hr practical per week for 12 weeks Prohibitions: CHEM1001 or CHEM1101 or CHEM1901 or CHEM1903 or CHEM1109 or CHEM1011 or CHEM1111 or CHEM1911 Assumed knowledge: 90 or above in HSC Chemistry or equivalent Assessment: quizzes, attendance, presentations, exam Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Department permission required for enrolment
Chemistry describes how and why things happen from a molecular perspective. Chemistry underpins all aspects of the natural and physical world, and provides the basis for new technologies and advances in the life, medical and physical sciences, engineering, and industrial processes. This unit of study will further develop your knowledge and skills in chemistry for application to life and medical sciences, engineering, and further study in chemistry. You will learn about nuclear and radiation chemistry, wave theory, atomic orbitals, spectroscopy, bonding, enthalpy and entropy, equilibrium, processes occurring in solutions, and the functional groups in carbon chemistry. You will develop experimental design, conduct and analysis skills in chemistry in small group projects. The laboratory program is designed to extend students who already have chemistry laboratory experience, and particularly caters for students who already show a passion and enthusiasm for research chemistry, as well as aptitude as demonstrated by high school chemistry results. Entry to Chemistry 1A (Special Studies Program) is restricted to a small number of students with an excellent school record in Chemistry, and applications must be made to the School of Chemistry. The practical work syllabus for Chemistry 1A (Special Studies Program) is very different from that for Chemistry 1A and Chemistry 1A (Advanced) and consists of special project-based laboratory exercises. All other unit of study details are the same as those for Chemistry 1A (Advanced).
Textbooks
Recommended textbook: Blackman, Bottle, Schmid, Mocerino and Wille,Chemistry, 3rd Edition, 2015 (John Wiley) ISBN: 978-0-7303-1105-8 (paperback) or 978-0-7303-2492-8 (e-text)
MEDS1001 Human Biology

Credit points: 6 Teacher/Coordinator: Prof Philip Poronnik Session: Semester 1 Classes: this unit of study will involve between 5-6 hours of face-to-face activities run on the camperdown campus, these contact hours will comprise lectures; six 3-hour practical sessions; six workshops and tutorials Prohibitions: BIOL1003 or BIOL1903 or BIOL1993 or BIOL1008 or BIOL1908 or BIOL1998 or MEDS1901 Assessment: Written and oral communication, quiz, practical and workshop reports, final exam Mode of delivery: Normal (lecture/lab/tutorial) day
What will it mean to be human in 2100? How will we be able to control our complex bodily mechanisms to maintain health and fight disease? Advances in the medical sciences suggest we will age more slowly and new technologies will enhance many bodily structures and functions. This unit of study will explore maintenance of health through nutritional balance, aerobic health, defence mechanisms and human diversity. You will learn key structural features from the subcellular level to the whole organ and body, and learn about essential functional pathways that determine how the body regulates its internal environment and responds to external stimuli and disease. Together we will investigate nutrition, digestion and absorption, cardiovascular and lung function, reproduction, development, epigenetics, and regulation of function through various interventions. You will receive lectures from experts in the field of human biology and medical sciences, supported by practical classes, workshops and on-line resources that leverage off state-of-the-art technologies to develop your practical, critical thinking, communication, collaboration, digital literacy, problem solving, and enquiry-based skills in human biology and medical sciences. This unit of study will provide you with the breadth and depth of knowledge and skills for further studies in the medical sciences.
Textbooks
TBA
MEDS coded units of study are only available to students in the Medical Science stream.

2000-level units of study

MIMI coded
MIMI2002 Microbes, Infection and Immunity

Credit points: 6 Teacher/Coordinator: Dr Leona Campbell Session: Semester 2 Classes: Lectures, online mini-lectures, discussion forums and self-directed learning activities; Face-to-face seminars, practicals, enquiry-, and scenario-based workshops (5 hours per week for 13 weeks). Prerequisites: (BIOL1XX7 or MBLG1XX1 or BIOL1XX8 or MEDS1X01 or BIOL1XX3) Prohibitions: MEDS2004 or BMED2404 or MIMI2902 or IMMU2101 or MICR2021 or MICR2921 or MICR2022 or MICR2922 or BMED2807 or BMED2808 Assumed knowledge: Human biology (BIOL1XX3 or BIOL1XX8 or MEDS1X01) and biological chemistry (CHEM1XX1 or CHEM1903) Assessment: final examination (40%), mid-semester examination (10%), practical exercises (20%), online activities (20%), integrated assessment (10%) Mode of delivery: Normal (lecture/lab/tutorial) day
Transmission, pathogenicity and immune response to microbes are key concepts for understanding infectious disease processes. In this unit of study you will establish a conceptual foundation and, using an integrated approach, explore selected case studies of infection from a body system of origin perspective. You will explore the characteristics of viral, bacterial, fungal and protist pathogens and their virulence mechanisms for establishment and progression of disease. Comprehensive consideration of host immune response and characteristic pathological changes to tissue that arise will then be considered. Upon completion of this unit, you will be able to explain microbial pathogenic processes of infection including: mechanisms for colonisation, invasion and damage to host tissue; the ways in which your immune system recognises and destroys invading microbes; how T cell response is activated and antibodies function. You will learn about pathogenesis, symptoms, current challenges of treatment including antibiotic resistance, control and vaccination strategies. You will develop a holistic perspective of infectious diseases. You will work collaboratively to solve challenging problems in Biomedical Sciences. Practical classes will investigate normal flora, host defences and case studies of medically important microbes with linkage to disease outcome. You will also obtain experience and understanding of modern experimental techniques in microbiology and immunopathology.
MIMI2902 Microbes, Infection and Immunity (Advanced)

Credit points: 6 Teacher/Coordinator: Dr Leona Campbell Session: Semester 2 Classes: Lectures, online lecturettes, discussion forums and self-directed learning activities; Face-to-face seminars, practicals, enquiry- and scenario-based workshops (5 hours per week for 13 weeks). Prerequisites: A mark of 70 or above in (BIOL1XX7 or MBLG1XX1 or BIOL1XX8 or MEDS1X01 or BIOL1XX3) Prohibitions: MEDS2004 or BMED2404 or MIMI2002 or IMMU2101 or MICR2021 or MICR2921 or MICR2022 or MICR2922 or BMED2807 or BMED2808 Assumed knowledge: Human biology (BIOL1XX3 or BIOL1XX8 or MEDS1X01) and biological chemistry (CHEM1XX1 or CHEM1903) Assessment: final examination (40%), mid-semester examination (10%), practical exercises (20%), formative online activities, research publication-based activities (20%), integrated assessment (10%) Mode of delivery: Normal (lecture/lab/tutorial) day
Transmission, pathogenicity and immune response to microbes are key concepts for understanding infectious disease processes. In this unit you will establish a conceptual foundation and, using an integrated approach, explore selected infection case studies from a body system of origin perspective. You will explore characteristics of viral, bacterial, fungal and protist pathogens and their virulence mechanisms for establishment and progression of disease. Comprehensive consideration of host immune response and consequent characteristic pathological changes to tissue will be considered. Upon completion, you will be able to explain microbial pathogenic processes of infection including: mechanisms for colonisation, invasion and damage to host tissue; the ways your immune system recognises and destroys invading microbes; how T cell response is activated and antibodies function. You will learn about pathogenesis, symptoms, current challenges of treatment including antibiotic resistance, control and vaccination strategies. This advanced unit has the same overall structure as MIMI2002 but contains a unique science communication exercise in which you will actively participate in small group sessions and be assessed with a short essay. This advanced component explores how recent advances in microbiology, infection and immunity are communicated to the wider public and is based on recent publications with potential high impact for society.
MEDS coded
MEDS2004 Microbes, Infection and Immunity

Credit points: 6 Teacher/Coordinator: Dr Leona Campbell Session: Semester 2 Classes: Online lecturettes, discussion forums and self-directed learning activities; Face-to-face seminars, practicals, enquiry-, multimedia module- and data analysis-based workshops (5 hours per week for 13 weeks). Prerequisites: BIOL1XX3 or BIOL1XX7 or BIOL1X08 or MEDS1X01 or MBLG1XX1 Prohibitions: MIMI2002 or MIMI2902 or MICR2021 or MICR2921 or MICR2022 or MICR2922 or IMMU2101 or BMED2404 or BMED2807 or BMED2808 Assumed knowledge: Human biology (BIOL1XX3 or BIOL1XX8 or MEDS1X01) and biological chemistry (CHEM1XX1 or CHEM1903) Assessment: final examination (40%), mid-semester examination (10%), practical exercises (20%), online activities (20%), integrated assessment (10%) Mode of delivery: Normal (lecture/lab/tutorial) day
Transmission, pathogenicity and immune response to microbes are key concepts for understanding infectious disease processes. In this unit of study you will establish a conceptual foundation and, using an integrated approach, explore selected case studies of infection from a body system of origin perspective. You will explore the characteristics of viral, bacterial, fungal and protist pathogens and their virulence mechanisms for establishment and progression of disease. Comprehensive consideration of host immune response and characteristic pathological changes to tissue that arise will then be considered. Upon completion of this unit, you will be able to explain microbial pathogenic processes of infection including: mechanisms for colonisation, invasion and damage to host tissue; the ways in which your immune system recognises and destroys invading microbes; how T cell response is activated and antibodies function. You will learn about pathogenesis, symptoms, current challenges of treatment including antibiotic resistance, control and vaccination strategies. You will develop a holistic perspective of infectious diseases. You will work collaboratively to solve challenging problems in Biomedical Sciences. Practical classes will investigate normal flora, host defences and case studies of medically important microbes with linkage to disease outcome. You will also obtain experience and understanding of modern experimental techniques in microbiology and immunopathology.
(MEDS coded units of study are only available to students in the Medical Science stream).
Selective
BCMB2001 Biochemistry and Molecular Biology

Credit points: 6 Teacher/Coordinator: Dr Dale Hancock Session: Semester 1 Classes: Three lectures per week; one 4-hour practical and one 1-hour tutorial session per fortnight Prerequisites: 6cp of (BIOL1XX7 or MBLG1XXX) and 6cp of (CHEM1XX1 or CHEM1903) Prohibitions: BCHM2072 or BCHM2972 or MBLG2071 or MBLG2971 or BMED2405 or BCMB2901 or MEDS2003 Assessment: Assignments, skills-based assessment, quizzes, exam Mode of delivery: Normal (lecture/lab/tutorial) day
Without cells, life as we know it would not exist. These dynamic assemblies, packed with biological molecules are constantly in action. But how do cells work? Why is the food that you eat so important for cellular function? How is information transmitted from generation to generation? And, what happens as a result of disease or genetic mutation? In this unit of study you will learn how cells work at the molecular level, with an emphasis on human biochemistry and molecular biology. We will focus initially on cellular metabolism and how cells extract and store energy from fuels like fats and carbohydrates, how the use of fuels is modulated in response to exercise, starvation and disease, and how other key metabolites are processed. Then we will explore how genetic information is regulated in eukaryotes, including replication, transcription and translation, and molecular aspects of the cell cycle, mitosis and meiosis. Our practicals, along with other guided and online learning sessions will introduce you to widely applied and cutting edge tools that are essential for modern biochemistry and molecular biology. By the end of this unit you will be equipped with foundational skills and knowledge to support your studies in the life and medical sciences.
Textbooks
Stryer Biochemistry 8th Edition ISBN-13:978-1-4641-2610-9
BCMB2901 Biochemistry and Molecular Biology (Advanced)

Credit points: 6 Teacher/Coordinator: Dr Dale Hancock Session: Semester 1 Classes: Three lectures per week; one 4-hour practical and one 1-hour tutorial session per fortnight Prerequisites: A mark of at least 70 from (BIOL1XX7 or MBLG1XX1) and (CHEM1XX1 or CHEM1903) Prohibitions: BCHM2072 or BCHM2972 or MBLG2071 or MBLG2971 or BMED2405 or BCMB2001 or MEDS2003 Assessment: Assignments, quiz, skills-based assessment, exam Mode of delivery: Normal (lecture/lab/tutorial) day
Without cells, life as we know it would not exist. These dynamic assemblies, packed with biological molecules are constantly in action. But how do cells work? Why is the food that you eat so important for cellular function? How is information transmitted from generation to generation? And, what happens as a result of disease or genetic mutation? In this unit of study you will learn how cells work at the molecular level, with an emphasis on human biochemistry and molecular biology. We will focus initially on cellular metabolism and how cells extract and store energy from fuels like fats and carbohydrates, how the use of fuels is modulated in response to exercise, starvation and disease, and how other key metabolites are processed. Then we will explore how genetic information is regulated in eukaryotes, including replication, transcription and translation, and molecular aspects of the cell cycle, mitosis and meiosis. The advanced laboratory component will provide students with an authentic research laboratory experience while in the theory component, current research topics will be presented in a problem-based format through dedicated advanced tutorial sessions. This material will be assessed by creative student-centered activities supported by eLearning platforms.
Textbooks
Stryer Biochemistry 8th Edition ISBN-13:978-1-4641-2610-9
IMMU2011 Immunobiology

Credit points: 6 Teacher/Coordinator: Dr Umaimainthan Palendira Session: Semester 1 Classes: Online lecturettes, weekly Interactive lectures, fortnightly Workshops and Practicals. ~4-5h face-to-face per week Prerequisites: BIOL1XX7 or (BIOL1XX8 or BIOL1XX3 or MEDS1X01) or BIOL1XX2 or MBLG1XX1 Prohibitions: IMMU2911 Assumed knowledge: CHEM1XX1 or CHEM1903 Assessment: Online quizzes (15%), practical reports (30%), title and abstract task (15%) and final exam (40%). Mode of delivery: Normal (lecture/lab/tutorial) day
Immunobiology is the study of defence mechanisms that protect living organisms against life-threatening infections. In this unit of study you will explore the essential features of the host immune responses mounted by animals, both vertebrates and invertebrates, plants and microbes themselves. Studies in animal and microbial immunobiology are leading to breakthroughs in veterinary and clinical medicine, including combatting infectious diseases, maximising transplant success, treating allergies, autoimmune diseases and cancer, as well as the development of new vaccines to prevent disease. Understanding the immunobiology of plants also enables us to protect crops from disease which enhances our food security. In this unit of study you will be provided with an overview of immunobiology as a basic research science. We will explore the nature of the immune cells and molecules that recognise danger and how the immune system of animals and plants respond at the cellular and molecular level. Practical and tutorial sessions are designed to illustrate particular concepts introduced in other face-to-face activities. Further self-directed learning activities, including online learning activities, will facilitate integration of fundamental information and help you apply this knowledge to the ways in which the host organism defends against disease. Upon completion, you will have developed the foundations to undertake further studies in Biology, Animal Health, Immunology and Pathology. Ultimately, this could lead you to a career in medical research, biosecurity and/or Veterinary Science.
Textbooks
Abbas, Lichtman and Pillai (2016) Basic Immunology: Functions and Disorders of The Immune System, 5th Edition
IMMU2911 Immunobiology (Advanced)

Credit points: 6 Teacher/Coordinator: Dr Umaimainthan Palendira Session: Semester 1 Classes: Online lecturettes, weekly Interactive lectures, fortnightly Workshops and Practicals . ~4-5h face-to-face per week Prerequisites: A mark of 70 or above in [BIOL1XX7 or (BIOL1XX8 or BIOL1XX3 or MEDS1X01) or BIOL1XX2 or MBLG1XX1] Prohibitions: IMMU2011 Assumed knowledge: CHEM1XX1 or CHEM1903 Assessment: Online quizzes (20%), practical reports (15%), journal article comprehension task (5%), title and abstract written task (10%) and final exam (50%) Mode of delivery: Normal (lecture/lab/tutorial) day
Immunobiology is the study of defence mechanisms that protect living organisms against life-threatening infections. In this unit of study you will explore the essential features of the host immune responses and how it evolved from unicellular organisms to complex multi-cellular organisms. Studies in animal and microbial immunobiology are leading to breakthroughs in veterinary and clinical medicine, including combatting infectious diseases, maximising transplant success, treating allergies, autoimmune diseases and cancer, as well as development of new vaccines to prevent disease. Understanding the immunobiology of plants also enables us to protect crops from disease which enhances our food security. In this unit of study you will be provided with a detailed overview of immunobiology as a basic research science. We will explore in detail the nature of the immune cells and molecules that recognise danger and how the immune system of animals and plants respond at the cellular and molecular level. Advanced practical and tutorial sessions are designed to illustrate particular concepts introduced in other face-to-face activities. Further self-directed learning activities, including online learning activities, will facilitate integration of fundamental information and help you apply this knowledge to the ways in which the host organism defends against disease. This advanced version of Immunobiology has the same overall concepts as the mainstream unit but material is discussed in a manner that offers a greater level of challenge and academic rigour. Students enrolled in the advanced stream will participate in alternative components which may for example include guest lectures from experts. The nature of these components may vary from year to year.
Textbooks
Abbas, Lichtman and Pillai (2016) Basic Immunology: Functions and Disorders of The Immune System, 5th Edition
MEDS2003 Biochemistry and Molecular Biology

Credit points: 6 Teacher/Coordinator: Dr Dale Hancock Session: Semester 1 Classes: Three lectures per week; one 4-hour practical session and 1 h tutorial per fortnight Prerequisites: 6p from (BIOL1XX7 or MBLG1XX1) and 6cp of (CHEM1XX1 or CHEM1903) Prohibitions: BCHM2072 or BCHM2972 or MBLG2071 or MBLG2971 or BMED2405 or BCMB2001 or BCMB2901 or BMED2804 Assessment: Group presentation (5%), In-class continuous assessment (25%), PeerWise MCQ design (10%), ELMA design essay and interpretation (10%), final exam (50%) Mode of delivery: Normal (lecture/lab/tutorial) day
Without cells, life as we know it would not exist. These dynamic assemblies, packed with biological molecules are constantly in action. But how do cells work? Why is the food that you eat so important for cellular function? How is information transmitted from generation to generation? What happens as a result of disease or genetic mutation? In this unit of study you will learn how cells work at the molecular level, with an emphasis on human biochemistry and molecular biology. We will focus initially on cellular metabolism and how cells extract and store energy from fuels like fats and carbohydrates, how fuel use is modulated in response to exercise, starvation and disease, and how other key metabolites are processed. Then we will explore how genetic information is regulated in eukaryotes, including replication, transcription and translation, and molecular aspects of the cell cycle, mitosis and meiosis. Our practicals, along with other guided and online learning sessions will introduce you to widely applied and cutting-edge tools that are essential for modern biochemistry and molecular biology. By the end of this unit you will be equipped with foundational skills and knowledge to support your studies in the medical and life sciences.
Textbooks
Canvas, ELN Peerwise Site, Blackboard LMS Textbook: Biochemistry - Berg, Tymoczko, Gatto, Stryer 8th Ed or higher Wikipedia
MICR2031 Microbiology

Credit points: 6 Teacher/Coordinator: A/Prof Michael Kertesz Session: Semester 1 Classes: Two 1-hour lectures per week; one 3-hour practical per week; five tutorial sessions Prohibitions: MICR2021 or MICR2921 or MICR2024 or MICR2931 Assumed knowledge: Fundamental concepts of microorganisms, biomolecules and ecosystems; CHEM1XX1 Assessment: Theory 60%: 45-minute mid-semester theory exam (20%) and 1.5-hour theory exam (40%); Practical 40%: written assignment (10%), group oral presentation (20%) and online quizzes (10%) Mode of delivery: Normal (lecture/lab/tutorial) day
Microbes are essential for every aspect of life on the planet. Microbes in the human gut control our digestion and our immune system, microbes in the soil are required for plant growth, microbes in the ocean fix more carbon dioxide than all the earth's trees. This unit of study will investigate the diversity and activity of microorganisms - viruses, bacteria, fungi, algae and protozoa - and look at how they interact with us, each other, plants and animals. You will examine how microbes underpin healthy ecosystems through nutrient cycling and biodegradation, their use industrially in biotechnology and food production, and their ability to cause harm, producing disease, poisoning, pollution and spoilage. Aspects of microbial ecology, nutrition, physiology and genetics will also be introduced. This unit of study will provide you with the breadth of knowledge and skills needed for further studies of microbiology, and will provide the fundamental understanding of microbes that you will require if you specialise in related fields such as biochemistry, molecular biology, immunology, agriculture, nutrition and food sciences, bioengineering and biotechnology, ecology or science education.
Textbooks
Willey et al, Prescott's Microbiology, 10th edition, McGraw-Hill, 2017
MICR2931 Microbiology (Advanced)

Credit points: 6 Teacher/Coordinator: A/Prof Michael Kertesz Session: Semester 1 Classes: Two 1-hour lectures per week; one 3-hour practical per week; five tutorial sessions Prerequisites: A mark of 70 or above in 6cp from (BIOL1XXX or MBLG1XXX) Prohibitions: MICR2021 or MICR2921 or MICR2024 or MICR2031 Assumed knowledge: Fundamental concepts of microorganisms, biomolecules and ecosystems; CHEM1XX1 Assessment: Theory 60%: 45-minute mid-semester theory exam (20%) and 1.5-hour theory exam (40%); Practical 40%: two written assignments (10%, 20%), and online quizzes (10%) Mode of delivery: Normal (lecture/lab/tutorial) day
Microbes are essential for every aspect of life on the planet. Microbes in the human gut control our digestion and our immune system, microbes in the soil are required for plant growth, microbes in the ocean fix more carbon dioxide than all the Earth's trees. In this unit of study you will investigate the diversity and activity of microorganisms - viruses, bacteria, fungi, algae and protozoa - and look at how they interact with us, each other, plants and animals. You will examine how microbes underpin healthy ecosystems through nutrient cycling and biodegradation, their use industrially in biotechnology and food production, and their ability to cause harm, producing disease, poisoning, pollution and spoilage. Detailed aspects of microbial ecology, nutrition, physiology and genetics will also be introduced. This unit of study will provide you with the breadth of knowledge and skills needed for further studies of microbiology, and will provide the fundamental understanding of microbes that you will require to specialise in related fields such as biochemistry, molecular biology, immunology, agriculture, nutrition and food sciences, bioengineering and biotechnology, ecology, or science education. As an Advanced unit, MICR2931 provides increased challenge and academic rigour to develop a greater understanding and depth of disciplinary expertise. You will actively participate in a series of small group tutorials investigating the molecular detail of microbial communication and function, which will culminate in you creating a scientific research report that communicates your understanding of recent research in microbiology.
Textbooks
Willey et al, Prescott's Microbiology, 10th edition, McGraw-Hill, 2017

3000-level units of study

Major core
INFD3012 Infectious Diseases

Credit points: 6 Teacher/Coordinator: A/Prof Jamie Triccas Session: Semester 2 Classes: Two 1 hour lectures and one 4 hour practical class per week. Prerequisites: BMED2404 or IMMU2101 or MEDS2004 or MIMI2X02 or IMMU2X11 Assessment: Formal examination (60%): one 2 hour exam. Progressive assessment (40%): includes tutorial case presentation, mid-semester quiz and practical assessment. Mode of delivery: Normal (lecture/lab/tutorial) day
Infectious diseases occur as a result of interactions between a host and a microbial parasite. This unit of study will explain how infectious agents interact with human hosts at the molecular, cellular, individual patient and community levels to cause diseases and how the hosts attempt to combat these infections. The unit will be taught by the discipline of Infectious Diseases and Immunology of the Department of Medicine within the Central Clinical School, Faculty of Medicine with involvement of associated clinical and research experts who will contribute lectures and theme sessions on their own special interests. The unit will integrate lectures with clinical case studies and hands-on practical sessions to provide students with current knowledge of infectious diseases.
Textbooks
Infectious Diseases: Pathogenesis, Prevention and Case Studies. Edited by Shetty et al. Wiley-Blackwell 2009. ISBN 9781405135436.
Major Selective
MICR3011 Microbes in Infection

Credit points: 6 Teacher/Coordinator: A/Prof Helen Agus Session: Semester 1 Classes: Two 1-hour lectures per week. Eight 3-hour practical sessions and three 2-hour clinical tutorials per semester Prerequisites: [6cp from (BIOL1XX7 or MBLGXXXX or GEGE2X01 or GENE2002) and 6cp from (MEDS2004 or MICR2X22 or MIMI2X02)] OR [BMED2401 and BMED2404] Prohibitions: MICR3911 Assumed knowledge: MICR2X21 or MICR2024 or MICR2X31 Assessment: Theory (60%): One 2-hour exam; Practical (40%): case study: worksheet, lab work, presentation; one quiz; one 1-hour theory of prac exam Mode of delivery: Normal (lecture/lab/tutorial) day
This unit is designed to further develop an interest in, and understanding of, medical microbiology from the introduction in Intermediate Microbiology. Through an examination of microbial structure, virulence, body defences and pathogenesis, the process of acquisition and establishment of disease is covered. The unit is divided into three themes: 1. Clinical Microbiology: host defences, infections, virulence mechanisms; 2. Public health microbiology: epidemiology, international public health, transmission, water and food borne outbreaks; 3. Emerging and re-emerging diseases: the impact of societal change with respect to triggering new diseases and causing the re-emergence of past problems, which are illustrated using case studies. The practical component is designed to enhance students' practical skills and to complement the lecture series. In these practical sessions experience will be gained handling live, potentially pathogenic microbes. Clinical tutorial sessions underpin and investigate the application of the material covered in the practical classes.
Textbooks
Murray PR et al. Medical Microbiology. 8th edition. Mosby. 2016.
MICR3911 Microbes in Infection (Advanced)

Credit points: 6 Teacher/Coordinator: A/Prof Helen Agus Session: Semester 1 Classes: Two 1-hour lectures per week including six 1-hour advanced sessions. Eight 3-hour practical sessions and three 2-hour clinical tutorials per semester Prerequisites: [6cp from (BIOL1XX7 or MBLGXXXX or GEGE2X01 or GENE2002) and a mark of 70 or above in (MEDS2004 or MICR2X22 or MIMI2X02)] OR [BMED2401 and a mark of 70 or above in BMED2404] Prohibitions: MICR3011 Assumed knowledge: MICR2X21 or MICR2024 or MICR2X31 Assessment: Theory: One 1.5-hour exam (45%), one essay (15%); Practical: case study worksheet (3%), case study lab work (7%), case study presentation (5%), quiz (10%), one 1-hour theory of prac exam (15%) Mode of delivery: Normal (lecture/lab/tutorial) day
This unit is available to students who have performed well in Intermediate Microbiology. This unit is designed to further develop an interest in, and understanding of, medical microbiology from the introduction in Intermediate Microbiology. Through an examination of microbial structure, virulence, body defences and pathogenesis, the process of acquisition and establishment of disease is covered. The unit is divided into three themes: 1. Clinical Microbiology: host defences, infections, virulence mechanisms; 2. Public health microbiology: epidemiology, international public health, transmission, water and food borne outbreaks; 3. Emerging and re-emerging diseases: the impact of societal change with respect to triggering new diseases and causing the re-emergence of past problems, which are illustrated using case studies. The unique aspect of this advanced unit that differentiates it from the mainstream unit is six tutorial style sessions that replace six mainstream lectures in the theme 'Emerging and re-emerging diseases'. These dedicated research-led interactive advanced sessions support self-directed learning and involve discussion around specific topics that will vary from year to year. Nominated research papers and reviews in the topic area will be explored with supported discussion of the relevance to and impact of the work on current thinking around emergence of microbial disease. The focus will be on microbial change that lies critically at the centre of understanding the reasons for the emergence of new diseases and challenges in an era of significant scientific ability to diagnose and treat infection. The practical component is identical to the mainstream unit and is designed to enhance students' practical skills and to complement the lectures. In these practical sessions experience will be gained handling live, potentially pathogenic microbes. Clinical tutorial sessions underpin and investigate the application of the material covered in the practical classes.
Textbooks
Murray PR.et al. Medical Microbiology. 8th ed., Mosby, 2016
VIRO3001 Virology

Credit points: 6 Teacher/Coordinator: A/Prof Tim Newsome Session: Semester 1 Classes: 26 1-hour lectures, seven 4-hour practical classes, one 2-hour tutorial Prerequisites: [6cp from (BIOL1XX7 or MBLGXXXX) and 6cp from (BCHM2XXX or BCMB2X01 or BIOL2XXX or GEGE2X01 or GENE2002 or IMMU2101 or MEDS2004 or MICR2XXX or MIMI2X02 or PCOL2X0X or PHSI2X0X)] OR [BMED2401 and BMED2404] Prohibitions: VIRO3901 Assumed knowledge: Fundamental concepts of microorganisms, biomolecules and ecosystems Assessment: preparation assessment for practical classes: (5 x 1%), practical assessment for practical classes: (5 x 2%), presentation on virology-themed research literature: (10%), theory of practical exam: (15%) (30 minutes), theory exam: (60%) (120 minutes) Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Students are strongly advised to complete VIRO3001 or VIRO3901 before enrolling in VIRO3002 or VIRO3902.
Viruses are some of the simplest biological machinery known yet they are also the etiological agents for some of the most important human diseases. New technologies that have revolutionised the discovery of viruses are also revealing a hitherto unappreciated abundance and diversity in the ecosphere, and a wider role in human health and disease. Developing new gene technologies have enabled the use of viruses as therapeutic agents, in novel vaccine approaches, gene delivery and in the treatment of cancer. This unit of study is designed to introduce students who have a basic understanding of molecular biology to the rapidly evolving field of virology. Viral infection in plant and animal cells and bacteria is covered by an examination of virus structure, genomes, gene expression and replication. Building upon these foundations, this unit progresses to examine host-virus interactions, pathogenesis, cell injury, the immune response and the prevention and control of infection and outbreaks. The structure and replication of sub-viral agents: viroids and prions, and their role in disease are also covered. The practical component provides hands-on experience in current diagnostic and research techniques such as molecular biology, cell culture, serological techniques, immunofluorescence and immunoblot analyses and is designed to enhance the students' practical skills and complement the lecture series. In these practical sessions experience will be gained handling live, potentially pathogenic microbes. Tutorials cover a range of topical issues and provide a forum for students to develop their communication and critical thinking skills. The unit will be taught by the Discipline of Microbiology within the School of Life and Environmental Sciences with the involvement of the Discipline of Infectious Diseases and Immunology within the Sydney Medical School.
Textbooks
Knipe and Howley. Fields Virology. 6th edition 2013. Available freely as an electronic resource from the University of Sydney library.
VIRO3901 Virology (Advanced)

Credit points: 6 Teacher/Coordinator: A/Prof Tim Newsome Session: Semester 1 Classes: 29 1-hour lectures, seven 4-hour practical classes, four 1-hour tutorials Prerequisites: [6cp from (BIOL1XX7 or MBLGXXXX) and a mark of 70 or above in 6cp from (BCHM2XXX or BCMB2X01 or BIOL2XXX or GEGE2X01 or GENE2002 or IMMU2101 or MEDS2004 or MICR2XXX or MIMI2X02 or PCOL2X0X or PHSI2X0X)] OR [BMED2401 and a mark of 70 or above in BMED2404] Prohibitions: VIRO3001 Assumed knowledge: Fundamental concepts of microorganisms, biomolecules and ecosystems Assessment: preparation assessment for practical classes: (5 x 1%), practical assessment for practical classes: (5 x 2%), presentation on virology-themed research literature: (10%), theory of practical exam: (15%) (30 minutes), theory exam (60%) (120 minutes) Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Students are strongly advised to complete VIRO3001 or VIRO3901 before enrolling in VIRO3002 or VIRO3902.
This unit is available to students who have performed well in Intermediate Microbiology and is based on VIRO3001 with additional lectures related to the research interests in the Discipline. Consequently, the unit of study content may change from year to year. Viruses are some of the simplest biological machinery known yet they are also the etiological agents for some of the most important human diseases. New technologies that have revolutionised the discovery of viruses are also revealing a hitherto unappreciated abundance and diversity in the ecosphere, and a wider role in human health and disease. Developing new gene technologies have enabled the use of viruses as therapeutic agents, in novel vaccine approaches, gene delivery and in the treatment of cancer. This unit of study is designed to introduce students who have a basic understanding of molecular biology to the rapidly evolving field of virology. Viral infection in plant and animal cells and bacteria is covered by an examination of virus structure, genomes, gene expression and replication. Building upon these foundations, this unit progresses to examine host-virus interactions, pathogenesis, cell injury, the immune response and the prevention and control of infection and outbreaks. The structure and replication of sub-viral agents: viroids and prions, and their role in disease are also covered. The practical component provides hands-on experience in current diagnostic and research techniques such as molecular biology, cell culture, serological techniques, immunofluroescence and immunoblot analyses and is designed to enhance the students' practical skills and complement the lecture series. In these practical sessions experience will be gained handling live, potentially pathogenic microbes. Advanced lectures cover cutting-edge research in the field of virology in small group discussions and presentations that provide a forum for students to develop their communication and critical thinking skills. The unit will be taught by the Discipline of Microbiology within the School of Life and Environmental Sciences with the involvement of the Discipline of Infectious Diseases and Immunology within the Sydney Medical School.
Textbooks
Knipe and Howley. Fields Virology. 6th edition 2013. Available freely as an electronic resource from the University of Sydney library.
VIRO3002 Medical and Applied Virology

Credit points: 6 Teacher/Coordinator: A/Prof Barry Slobedman Session: Semester 2 Classes: Two 1-hour lectures per week Prerequisites: 6cp from (BMED2404 or IMMU2101 or MEDS2004 or MIMI2X02 or MICR2X22) Prohibitions: VIRO3902 Assumed knowledge: Fundamental concepts of microorganisms and biomolecules Assessment: One 2-hour exam covering lecture material, one 2-hour theory of practical exam, written assignment and oral presentation (100%) Practical field work: One 4 hour practical session per week, in most weeks of semester. Practical session slots are also used for oral presentations. Mode of delivery: Normal (lecture/lab/tutorial) day
This unit of study explores diseases in human caused by viruses, with focus on the way viruses infect individual patients and spread in the community, and how virus infections are diagnosed, treated and/or prevented. Host/Virus interactions will also be described with a focus on the viral mechanisms that have evolved to combat and/or evade host defence systems. These features will be used to explain the symptoms, spread and control of the most medically important viruses that cause serious disease in humans. The unit will be taught by the Discipline of Infectious Diseases and Immunology within the Sydney Medical School with the involvement of associated clinical and research experts who will contribute lectures on their own special interests and with contributions from the Discipline of Microbiology. In the practical classes students will have the opportunity to develop their skills in performing methods currently used in diagnostic and research laboratories such as molecular analysis of viral genomes, immunofluorescent staining of viral antigens, cell culture and the culture of viruses.
Textbooks
Knipe and Howley. Fields Virology. 6th edition 2013. Available freely as an electronic resource from the University of Sydney library.
VIRO3902 Medical and Applied Virology (Advanced)

Credit points: 6 Teacher/Coordinator: A/Prof Barry Slobedman Session: Semester 2 Classes: Two 1 hour lectures per week, and one interactive 2-hour tutorials (approx 6 in total, including for oral presentations) Prerequisites: A mark of 70 or above in 6cp from (BMED2404 or IMMU2101 or MEDS2004 or MIMI2X02 or MICR2X22) Prohibitions: VIRO3002 Assumed knowledge: Fundamental concepts of microorganisms and biomolecules Assessment: One 2-hour exam covering lecture material, one 2-hour theory of practical exam, written assignment, oral presentation and tutorial participation (100%) Practical field work: One 4 hour practical session per week, in most weeks of semester. Mode of delivery: Normal (lecture/lab/tutorial) day
This unit is based on the VIRO3002 course with inclusion of tutorials, including with leading research medical virologists, enabling students to gain additional experience with cutting edge virology research. The content of this unit may change from year to year based on research interests within the department.
Textbooks
Knipe and Howley. Fields Virology. 6th edition 2013. Available freely as an electronic resource from the University of Sydney library.
Interdisciplinary project
INFD3888 Infectious Diseases Interdisciplinary Project

Credit points: 6 Teacher/Coordinator: Prof Jamie Triccas Session: Semester 2 Classes: Lecture 2 hrs/week; tutorial 1 hr/week; workshop 2hr/week Prerequisites: 12cp from [(MEDS2004 or MIMI2002 or MIMI2902 or BMED2404) or (MICR2022 or MICR2922) or (MEDS2003 or BCMB2001 or BCMB2901) or (IMMU2011 or IMMU2911)] Assessment: Assignments and written exam (50%), Project report (20%), Project oral presentation (10%), Team work participation and evaluation (20%). Mode of delivery: Block mode
Our ever-changing world requires knowledge that extends across multiple disciplines. The ability to identify and explore interdisciplinary links is a crucial skill for emerging professionals and researchers alike. This unit presents the opportunity to bring together the concepts and skills you have learnt in your discipline and apply them to a real-world problem. For example, you will work on a project titled 'beating the superbugs' an interdisciplinary project that assesses the pipeline of anti-microbial discovery and delivery based on discipline skills in bacterial and viral infections, medicinal chemistry and drug development, pharmacodynamics, anti-microbial resistance, and disease control and cure. In this unit, you will continue to understand and explore disciplinary knowledge, while also meeting and collaborating with students from across the University through project-based learning; identifying and solving problems, collecting and analysing data and communicating your findings to a diverse audience. All of these skills are highly valued by employers. This unit will foster the ability to work in interdisciplinary teams, and this is essential for both professional and research pathways in future.
SCPU3001 Science Interdisciplinary Project

Credit points: 6 Teacher/Coordinator: Prof Pauline Ross Session: Intensive February,Intensive July,Semester 1,Semester 2 Classes: The unit consists of one seminar/workshop per week with accompanying online materials and a project to be determined in consultation with the partner organisation and completed as part of a team with academic supervision. Prerequisites: Completion of 2000-level units required for at least one Science major. Assessment: group plan, group presentation, reflective journal, group project Mode of delivery: Normal (lecture/lab/tutorial) day
This unit is designed for students who are concurrently enrolled in at least one 3000-level Science Table A unit of study to undertake a project that allows them to work with one of the University's industry and community partners. Students will work in teams on a real-world problem provided by the partner. This experience will allow students to apply their academic skills and disciplinary knowledge to a real-world issue in an authentic and meaningful way. Participation in this unit will require students to submit an application to the Faculty of Science.
Minor core
INFD3012 Infectious Diseases

Credit points: 6 Teacher/Coordinator: A/Prof Jamie Triccas Session: Semester 2 Classes: Two 1 hour lectures and one 4 hour practical class per week. Prerequisites: BMED2404 or IMMU2101 or MEDS2004 or MIMI2X02 or IMMU2X11 Assessment: Formal examination (60%): one 2 hour exam. Progressive assessment (40%): includes tutorial case presentation, mid-semester quiz and practical assessment. Mode of delivery: Normal (lecture/lab/tutorial) day
Infectious diseases occur as a result of interactions between a host and a microbial parasite. This unit of study will explain how infectious agents interact with human hosts at the molecular, cellular, individual patient and community levels to cause diseases and how the hosts attempt to combat these infections. The unit will be taught by the discipline of Infectious Diseases and Immunology of the Department of Medicine within the Central Clinical School, Faculty of Medicine with involvement of associated clinical and research experts who will contribute lectures and theme sessions on their own special interests. The unit will integrate lectures with clinical case studies and hands-on practical sessions to provide students with current knowledge of infectious diseases.
Textbooks
Infectious Diseases: Pathogenesis, Prevention and Case Studies. Edited by Shetty et al. Wiley-Blackwell 2009. ISBN 9781405135436.
MICR3011 Microbes in Infection

Credit points: 6 Teacher/Coordinator: A/Prof Helen Agus Session: Semester 1 Classes: Two 1-hour lectures per week. Eight 3-hour practical sessions and three 2-hour clinical tutorials per semester Prerequisites: [6cp from (BIOL1XX7 or MBLGXXXX or GEGE2X01 or GENE2002) and 6cp from (MEDS2004 or MICR2X22 or MIMI2X02)] OR [BMED2401 and BMED2404] Prohibitions: MICR3911 Assumed knowledge: MICR2X21 or MICR2024 or MICR2X31 Assessment: Theory (60%): One 2-hour exam; Practical (40%): case study: worksheet, lab work, presentation; one quiz; one 1-hour theory of prac exam Mode of delivery: Normal (lecture/lab/tutorial) day
This unit is designed to further develop an interest in, and understanding of, medical microbiology from the introduction in Intermediate Microbiology. Through an examination of microbial structure, virulence, body defences and pathogenesis, the process of acquisition and establishment of disease is covered. The unit is divided into three themes: 1. Clinical Microbiology: host defences, infections, virulence mechanisms; 2. Public health microbiology: epidemiology, international public health, transmission, water and food borne outbreaks; 3. Emerging and re-emerging diseases: the impact of societal change with respect to triggering new diseases and causing the re-emergence of past problems, which are illustrated using case studies. The practical component is designed to enhance students' practical skills and to complement the lecture series. In these practical sessions experience will be gained handling live, potentially pathogenic microbes. Clinical tutorial sessions underpin and investigate the application of the material covered in the practical classes.
Textbooks
Murray PR et al. Medical Microbiology. 8th edition. Mosby. 2016.
MICR3911 Microbes in Infection (Advanced)

Credit points: 6 Teacher/Coordinator: A/Prof Helen Agus Session: Semester 1 Classes: Two 1-hour lectures per week including six 1-hour advanced sessions. Eight 3-hour practical sessions and three 2-hour clinical tutorials per semester Prerequisites: [6cp from (BIOL1XX7 or MBLGXXXX or GEGE2X01 or GENE2002) and a mark of 70 or above in (MEDS2004 or MICR2X22 or MIMI2X02)] OR [BMED2401 and a mark of 70 or above in BMED2404] Prohibitions: MICR3011 Assumed knowledge: MICR2X21 or MICR2024 or MICR2X31 Assessment: Theory: One 1.5-hour exam (45%), one essay (15%); Practical: case study worksheet (3%), case study lab work (7%), case study presentation (5%), quiz (10%), one 1-hour theory of prac exam (15%) Mode of delivery: Normal (lecture/lab/tutorial) day
This unit is available to students who have performed well in Intermediate Microbiology. This unit is designed to further develop an interest in, and understanding of, medical microbiology from the introduction in Intermediate Microbiology. Through an examination of microbial structure, virulence, body defences and pathogenesis, the process of acquisition and establishment of disease is covered. The unit is divided into three themes: 1. Clinical Microbiology: host defences, infections, virulence mechanisms; 2. Public health microbiology: epidemiology, international public health, transmission, water and food borne outbreaks; 3. Emerging and re-emerging diseases: the impact of societal change with respect to triggering new diseases and causing the re-emergence of past problems, which are illustrated using case studies. The unique aspect of this advanced unit that differentiates it from the mainstream unit is six tutorial style sessions that replace six mainstream lectures in the theme 'Emerging and re-emerging diseases'. These dedicated research-led interactive advanced sessions support self-directed learning and involve discussion around specific topics that will vary from year to year. Nominated research papers and reviews in the topic area will be explored with supported discussion of the relevance to and impact of the work on current thinking around emergence of microbial disease. The focus will be on microbial change that lies critically at the centre of understanding the reasons for the emergence of new diseases and challenges in an era of significant scientific ability to diagnose and treat infection. The practical component is identical to the mainstream unit and is designed to enhance students' practical skills and to complement the lectures. In these practical sessions experience will be gained handling live, potentially pathogenic microbes. Clinical tutorial sessions underpin and investigate the application of the material covered in the practical classes.
Textbooks
Murray PR.et al. Medical Microbiology. 8th ed., Mosby, 2016