Immunology and Pathology Descriptions

IMMUNOLOGY AND PATHOLOGY

Immunology and Pathology major

A major in Immunology and Pathology requires 48 credit points from this table including:

(i) 6 credit points of 1000-level core units

(ii) 6 credit points of 1000-level selective units

(iii) 6 credit points of 2000-level core units according to the following:

(a) 6 credit points of 2000-level MIMI coded units or

(b) 6 credit points of 2000-level MEDS coded units for students in the Medical Science stream

(iv) 6 credit points of 2000-level selective units

(v) 12 credit points of 3000-level core units

(vi) 6 credit points of 3000-level selective units

(vii) 6 credit points of 3000-level interdisciplinary project units

Units of study

The units of study are listed below.

1000-level units of study

Core

CHEM1011 Fundamentals of Chemistry 1A

Credit points: 6 Teacher/Coordinator: Dr Toby Hudson Session: Semester 1 Classes: 3x1-hr lectures; 1x1-hr tutorial per week; 1x3-hr practical per week for 9 weeks Prohibitions: CHEM1001 or CHEM1101 or CHEM1901 or CHEM1903 or CHEM1109 or CHEM1111 or CHEM1911 or CHEM1991 Assumed knowledge: There is no assumed knowledge of chemistry for this unit of study but students who have not completed HSC Chemistry (or equivalent) are strongly advised to take the Chemistry Bridging Course (offered in February). Assessment: quizzes, attendance, laboratory log book, exam Mode of delivery: Normal (lecture/lab/tutorial) day

Note: Students who have not completed HSC Chemistry (or equivalent) are strongly advised to take the Chemistry Bridging Course (offered in February, and online year-round, see https://sydney.edu.au/students/bridging-courses.html).

Chemistry describes how and why things happen from a molecular perspective. Chemistry underpins all aspects of the natural and physical world, and provides the basis for new technologies and advances in the life, medical and physical sciences, engineering, and industrial processes. This unit of study will equip you with the fundamental knowledge and skills in chemistry for broad application. You will learn about atomic theory, structure and bonding, equilibrium, processes occurring in solutions, and the functional groups of molecules. You will develop experimental design, conduct and analysis skills in chemistry through experiments that ask and answer questions about the chemical nature and processes occurring around you. Through inquiry, observation and measurement, you will better understand natural and physical world and will be able to apply this understanding to real-world problems and solutions. This unit of study is directed toward students whose chemical background is weak (or non-existent). Compared to the mainstream Chemistry 1A, the theory component of this unit begins with more fundamental concepts, and does not cover, or goes into less detail about some topics. Progression to intermediate chemistry from this unit and Fundamentals of Chemistry 1B requires completion of an online supplementary course.

Textbooks

Recommended textbook: Blackman, Bottle, Schmid, Mocerino and Wille,Chemistry, 3rd Edition, 2015 (John Wiley) ISBN: 978-0-7303-1105-8 (paperback) or 978-0-7303-2492-8 (e-text)

CHEM1111 Chemistry 1A

Credit points: 6 Teacher/Coordinator: Dr Toby Hudson Session: Intensive January,Semester 1,Semester 2 Classes: 3x1-hr lectures; 1x1-hr tutorial per week; 1x3-hr practical per week for 9 weeks Prohibitions: CHEM1001 or CHEM1101 or CHEM1901 or CHEM1903 or CHEM1109 or CHEM1011 or CHEM1911 or CHEM1991 Assumed knowledge: Students who have not completed HSC Chemistry (or equivalent) and HSC Mathematics (or equivalent) are strongly advised to take the Chemistry and Mathematics Bridging Courses (offered in February) Assessment: quizzes, attendance, laboratory log book, exam Mode of delivery: Normal (lecture/lab/tutorial) day

Note: Students who have not completed secondary school chemistry are strongly advised to instead complete Fundamentals of Chemistry 1A in the first semester of the calendar year (unless you require 12 credit points of Chemistry and are commencing in semester 2). You should also take the Chemistry Bridging Course in advance (offered in February, and online year-round https://sydney.edu.au/students/bridging-courses.html).

Chemistry describes how and why things happen from a molecular perspective. Chemistry underpins all aspects of the natural and physical world, and provides the basis for new technologies and advances in the life, medical and physical sciences, engineering, and industrial processes. This unit of study will further develop your knowledge and skills in chemistry for application to life and medical sciences, engineering, and further study in chemistry. You will learn about nuclear and radiation chemistry, wave theory, atomic orbitals, spectroscopy, bonding, enthalpy and entropy, equilibrium, processes occurring in solutions, and the functional groups in carbon chemistry. You will develop experimental design, conduct and analysis skills in chemistry through experiments that ask and answer questions like how do dyes work, how do we desalinate water, how do we measure the acid content in foods, how do we get the blue in a blueprint, and how do we extract natural products from plants? Through inquiry, observation and measurement, you will understand the 'why' and the 'how' of the natural and physical world and will be able to apply this understanding to real-world problems and solutions. This unit of study is directed toward students with a satisfactory prior knowledge of the HSC chemistry course.

Textbooks

Recommended textbook: Blackman, Bottle, Schmid, Mocerino and Wille,Chemistry, 3rd Edition, 2015 (John Wiley) ISBN: 978-0-7303-1105-8 (paperback) or 978-0-7303-2492-8 (e-text)

CHEM1911 Chemistry 1A (Advanced)

Credit points: 6 Teacher/Coordinator: Dr Toby Hudson Session: Semester 1 Classes: 3x1-hr lectures and 1x1-hr tutorial per week; 1x3-hr practical per week for 9 weeks Prohibitions: CHEM1001 or CHEM1101 or CHEM1901 or CHEM1903 or CHEM1109 or CHEM1011 or CHEM1111 or CHEM1991 Assumed knowledge: 80 or above in HSC Chemistry or equivalent Assessment: quizzes, attendance, laboratory log book, exam Mode of delivery: Normal (lecture/lab/tutorial) day

Note: Department permission required for enrolment

Chemistry describes how and why things happen from a molecular perspective. Chemistry underpins all aspects of the natural and physical world, and provides the basis for new technologies and advances in sciences, engineering, and industrial processes. This unit of study will further develop your knowledge and skills in chemistry for broad application, including further study in chemistry. You will learn about nuclear and radiation chemistry, wave theory, atomic orbitals, spectroscopy, bonding, enthalpy and entropy, equilibrium, processes occurring in solutions, and the functional groups of molecules. You will develop experimental design, conduct and analysis skills in chemistry through experiments that ask and answer questions about the chemical nature and processes occurring around you. Through inquiry, observation and measurement, you will better understand natural and physical world and will be able to apply this understanding to real-world problems and solutions. This unit of study is directed toward students with a good secondary performance both overall and in chemistry or science. Students in this category are expected to do this unit rather than Chemistry 1A. Compared to the mainstream Chemistry 1A, the theory component of this unit provides a higher level of academic rigour and makes broader connections between topics.

Textbooks

Recommended textbook: Blackman, Bottle, Schmid, Mocerino and Wille,Chemistry, 3rd Edition, 2015 (John Wiley) ISBN: 978-0-7303-1105-8 (paperback) or 978-0-7303-2492-8 (e-text)

CHEM1991 Chemistry 1A (Special Studies Program)

Credit points: 6 Teacher/Coordinator: Dr Toby Hudson Session: Semester 1 Classes: 3x1-hr lectures; 1x1-hr tutorial per week; 1x3hr practical per week for 12 weeks Prohibitions: CHEM1001 or CHEM1101 or CHEM1901 or CHEM1903 or CHEM1109 or CHEM1011 or CHEM1111 or CHEM1911 Assumed knowledge: 90 or above in HSC Chemistry or equivalent Assessment: quizzes, attendance, presentations, exam Mode of delivery: Normal (lecture/lab/tutorial) day

Note: Department permission required for enrolment

Chemistry describes how and why things happen from a molecular perspective. Chemistry underpins all aspects of the natural and physical world, and provides the basis for new technologies and advances in the life, medical and physical sciences, engineering, and industrial processes. This unit of study will further develop your knowledge and skills in chemistry for application to life and medical sciences, engineering, and further study in chemistry. You will learn about nuclear and radiation chemistry, wave theory, atomic orbitals, spectroscopy, bonding, enthalpy and entropy, equilibrium, processes occurring in solutions, and the functional groups in carbon chemistry. You will develop experimental design, conduct and analysis skills in chemistry in small group projects. The laboratory program is designed to extend students who already have chemistry laboratory experience, and particularly caters for students who already show a passion and enthusiasm for research chemistry, as well as aptitude as demonstrated by high school chemistry results. Entry to Chemistry 1A (Special Studies Program) is restricted to a small number of students with an excellent school record in Chemistry, and applications must be made to the School of Chemistry. The practical work syllabus for Chemistry 1A (Special Studies Program) is very different from that for Chemistry 1A and Chemistry 1A (Advanced) and consists of special project-based laboratory exercises. All other unit of study details are the same as those for Chemistry 1A (Advanced).

Textbooks

Recommended textbook: Blackman, Bottle, Schmid, Mocerino and Wille,Chemistry, 3rd Edition, 2015 (John Wiley) ISBN: 978-0-7303-1105-8 (paperback) or 978-0-7303-2492-8 (e-text)

Selective

BIOL1007 From Molecules to Ecosystems

Credit points: 6 Teacher/Coordinator: Dr Osu Lilje Session: Semester 2 Classes: 2-3 lectures per week and online material and 12 x 3-hour practicals Prohibitions: BIOL1907 or BIOL1997 Assumed knowledge: HSC Biology. Students who have not completed HSC Biology (or equivalent) are strongly advised to take the Biology Bridging Course (offered in February). Assessment: quizzes (15%), communication assessments (35%), proficiency assessment (10%), final exam (40%) Mode of delivery: Normal (lecture/lab/tutorial) day

Paradigm shifts in biology have changed the emphasis from single biomolecule studies to complex systems of biomolecules, cells and their interrelationships in ecosystems of life. Such an integrated understanding of cells, biomolecules and ecosystems is key to innovations in biology. Life relies on organisation, communication, responsiveness and regulation at every level. Understanding biological mechanisms, improving human health and addressing the impact of human activity are the great challenges of the 21st century. This unit will investigate life at levels ranging from cells, and biomolecule ecosystems, through to complex natural and human ecosystems. You will explore the importance of homeostasis in health and the triggers that lead to disease and death. You will learn the methods of cellular, biomolecular, microbial and ecological investigation that allow us to understand life and discover how expanding tools have improved our capacity to manage and intervene in ecosystems for our own health and organisms in the environment that surround and support us . You will participate in inquiry-led practicals that reinforce the concepts in the unit. By doing this unit you will develop knowledge and skills that will enable you to play a role in finding global solutions that will impact our lives.

Textbooks

Please see unit outline on LMS

BIOL1907 From Molecules to Ecosystems (Advanced)

Credit points: 6 Teacher/Coordinator: Dr Claudia Keitel Session: Semester 2 Classes: 2-3 lectures per week and online material and 12 x 3-hour practicals Prohibitions: BIOL1007 or BIOL1997 Assumed knowledge: 85 or above in HSC Biology or equivalent Assessment: quizzes (14%), communication assessments (36%), proficiency assessment (10%), final exam (40%) Mode of delivery: Normal (lecture/lab/tutorial) day

Note: Department permission required for enrolment

Paradigm shifts in biology have changed the emphasis from single biomolecule studies to complex systems of biomolecules, cells and their interrelationships in ecosystems of life. Such an integrated understanding of cells, biomolecules and ecosystems is key to innovations in biology. Life relies on organisation, communication, responsiveness and regulation at every level. Understanding biological mechanisms, improving human health and addressing the impact of human activity are the great challenges of the 21st century. This unit will investigate life at levels ranging from cells, and biomolecule ecosystems, through to complex natural and human ecosystems. You will explore the importance of homeostasis in health and the triggers that lead to disease and death. You will learn the methods of cellular, biomolecular, microbial and ecological investigation that allow us to understand life and discover how expanding tools have improved our capacity to manage and intervene in ecosystems for our own health and organisms in the environment that surround and support us . This unit of study has the same overall structure as BIOL1007 but material is discussed in greater detail and at a more advanced level. The content and nature of these components may vary from year to year.

Textbooks

Please see unit outline on LMS

BIOL1997 From Molecules to Ecosystems (SSP)

Credit points: 6 Teacher/Coordinator: Dr Emma Thompson Session: Semester 2 Classes: 2-3 lectures per week; online material; and 12 x 3-hour practicals Prohibitions: BIOL1007 or BIOL1907 Assumed knowledge: 90 or above in HSC Biology or equivalent Assessment: One 2-hour exam (40%), project report which includes written report and presentation (60%) Mode of delivery: Normal (lecture/lab/tutorial) day

Note: Department permission required for enrolment

Paradigm shifts in biology have changed the emphasis from single biomolecule studies to complex systems of biomolecules, cells and their interrelationships in ecosystems of life. Such an integrated understanding of cells, biomolecules and ecosystems is key to innovations in biology. Life relies on organisation, communication, responsiveness and regulation at every level. Understanding biological mechanisms, improving human health and addressing the impact of human activity are the great challenges of the 21st century. This unit will investigate life at levels ranging from cells, and biomolecule ecosystems, through to complex natural and human ecosystems. You will explore the importance of homeostasis in health and the triggers that lead to disease and death. You will learn the methods of cellular, biomolecular, microbial and ecological investigation that allow us to understand life and intervene in ecosystems to improve health. The same theory will be covered as in the advanced stream but in this Special Studies Unit, the practical component is a research project. The research will be a synthetic biology project investigating genetically engineered organisms. Students will have the opportunity to develop higher level generic skills in computing, communication, critical analysis, problem solving, data analysis and experimental design.

Textbooks

Please see unit outline on LMS

BIOL1008 Human Biology

Credit points: 6 Teacher/Coordinator: Dr Hong Dao Nguyen Session: Semester 1 Classes: This unit of study will involve between 5-6 hours of face-to-face activities run on the Camperdown campus. These contact hours will comprise 2-3 hours of lectures per week; six 3 hour practical sessions; six 3 hour workshops/tutorials Prohibitions: BIOL1003 or BIOL1903 or BIOL1993 or MEDS1001 or MEDS1901 or BIOL1908 or BIOL1998 Assumed knowledge: HSC Biology. Students who have not completed HSC Biology (or equivalent) are strongly advised to take the Biology Bridging Course (offered in February). Assessment: post-module quizzes (10%), Living Data (25%), scientific report (20%), skills test (5%), final exam (40%) Practical field work: Six 3 hour lab classes Mode of delivery: Normal (lecture/lab/tutorial) day

What will it mean to be human in 2100? How will we be able to control our complex bodily mechanisms to maintain health and fight disease? Advances in the human biology suggest we will age more slowly and new technologies will enhance many bodily structures and functions. This unit of study will explore maintenance of health through nutritional balance, aerobic health, defence mechanisms and human diversity. You will learn key structural features from the subcellular level to the whole organ and body, and learn about essential functional pathways that determine how the body regulates its internal environment and responds to external stimuli and disease. Together we will investigate nutrition, digestion and absorption, cardiovascular and lung function, reproduction, development, epigenetics, and regulation of function through various interventions. You will receive lectures from experts in the field of human biology and medical sciences, supported by practical classes, workshops and on-line resources that leverage off state-of-the-art technologies to develop your practical, critical thinking, communication, collaboration, digital literacy, problem solving, and enquiry-based skills in human biology. This unit of study will provide you with the breadth and depth of knowledge and skills for further studies in majors in medical sciences.

Textbooks

Van Putte, C., Regan, J. and Russo, A. (*) Essentials of Anatomy and Physiology, McGraw Hill.

BIOL1908 Human Biology (Advanced)

Credit points: 6 Teacher/Coordinator: Dr Hong Dao Nguyen Session: Semester 1 Classes: This unit of study will involve between 5-6 hours of face-to-face activities run on the Camperdown campus. These contact hours will comprise 2-3 hours of lectures per week; six 3-hour practical sessions; six 3-hour workshops/tutorials Prohibitions: BIOL1003 or BIOL1903 or BIOL1993 or MEDS1001 or MEDS1901 or BIOL1008 or BIOL1998 Assumed knowledge: 85 or above in HSC Biology or equivalent Assessment: post-module quizzes (10%), Living Data (25%), scientific report (20%), skills test (5%), final exam (40%) Practical field work: Six 3 hour practicals Mode of delivery: Normal (lecture/lab/tutorial) day

Note: Department permission required for enrolment

Textbooks

Van Putte, C., Regan, J. and Russo, A. (*) Essentials of Anatomy and Physiology, McGraw Hill.

BIOL1998 Human Biology (Special Studies Program)

Credit points: 6 Teacher/Coordinator: Dr Rosalyn Gloag Session: Semester 1 Classes: Lectures as per BIOL1908; one 3-hour practical per week Prohibitions: BIOL1003 or BIOL1903 or BIOL1993 or BIOL1991 or BIOL1996 or MEDS1001 or MEDS1901 or BIOL1008 or BIOL1908 Assumed knowledge: 90 or above in HSC Biology or equivalent Assessment: One 2-hour exam (50%), practical report (25%), practical presentation (15%), lab note book (5%), pre laboratory quizzes (5%) Mode of delivery: Normal (lecture/lab/tutorial) day

Note: Department permission required for enrolment

What will it mean to be human in 2100? How will we be able to control our complex bodily mechanisms to maintain health and fight disease? Advances in human biology suggest we will age more slowly and new technologies will enhance many bodily structures and functions. This unit of study will explore maintenance of health through nutritional balance, aerobic health, defence mechanisms and human diversity. You will learn key structural features from the subcellular level to the whole organ and body, and learn about essential functional pathways that determine how the body regulates its internal environment and responds to external stimuli and disease. Together we will investigate nutrition, digestion and absorption, cardiovascular and lung function, reproduction, development, epigenetics, and regulation of function through various interventions. You will receive lectures from experts in the field of human biology and medical sciences, supported by practical classes, workshops and on-line resources that leverage off state-of-the-art technologies to develop your practical, critical thinking, communication, collaboration, digital literacy, problem solving, and enquiry-based skills in human biology. This unit of study will provide you with the breadth and depth of knowledge and skills for further studies in majors in medical sciences. The practical work syllabus consists of a special project-based laboratory.

Textbooks

Van Putte, C., Regan, J. and Russo, A. (*) Essentials of Anatomy and Physiology, McGraw Hill.

MEDS1001 Human Biology

Credit points: 6 Teacher/Coordinator: Prof Philip Poronnik Session: Semester 1 Classes: this unit of study will involve between 5-6 hours of face-to-face activities run on the camperdown campus, these contact hours will comprise lectures; six 3-hour practical sessions; six workshops and tutorials Prohibitions: BIOL1003 or BIOL1903 or BIOL1993 or BIOL1008 or BIOL1908 or BIOL1998 or MEDS1901 Assessment: Written and oral communication, quiz, practical and workshop reports, final exam Mode of delivery: Normal (lecture/lab/tutorial) day

What will it mean to be human in 2100? How will we be able to control our complex bodily mechanisms to maintain health and fight disease? Advances in the medical sciences suggest we will age more slowly and new technologies will enhance many bodily structures and functions. This unit of study will explore maintenance of health through nutritional balance, aerobic health, defence mechanisms and human diversity. You will learn key structural features from the subcellular level to the whole organ and body, and learn about essential functional pathways that determine how the body regulates its internal environment and responds to external stimuli and disease. Together we will investigate nutrition, digestion and absorption, cardiovascular and lung function, reproduction, development, epigenetics, and regulation of function through various interventions. You will receive lectures from experts in the field of human biology and medical sciences, supported by practical classes, workshops and on-line resources that leverage off state-of-the-art technologies to develop your practical, critical thinking, communication, collaboration, digital literacy, problem solving, and enquiry-based skills in human biology and medical sciences. This unit of study will provide you with the breadth and depth of knowledge and skills for further studies in the medical sciences.

Textbooks

TBA

MEDS coded units of study are only available to students in the Medical Science stream.

2000-level units of study

MIMI coded

MIMI2002 Microbes, Infection and Immunity

Credit points: 6 Teacher/Coordinator: Dr Leona Campbell Session: Semester 2 Classes: Lectures, online mini-lectures, discussion forums and self-directed learning activities; Face-to-face seminars, practicals, enquiry-, and scenario-based workshops (5 hours per week for 13 weeks). Prerequisites: (BIOL1XX7 or MBLG1XX1 or BIOL1XX8 or MEDS1X01 or BIOL1XX3) Prohibitions: MEDS2004 or BMED2404 or MIMI2902 or IMMU2101 or MICR2021 or MICR2921 or MICR2022 or MICR2922 or BMED2807 or BMED2808 Assumed knowledge: Human biology (BIOL1XX3 or BIOL1XX8 or MEDS1X01) and biological chemistry (CHEM1XX1 or CHEM1903) Assessment: final examination (40%), mid-semester examination (10%), practical exercises (20%), online activities (20%), integrated assessment (10%) Mode of delivery: Normal (lecture/lab/tutorial) day

Transmission, pathogenicity and immune response to microbes are key concepts for understanding infectious disease processes. In this unit of study you will establish a conceptual foundation and, using an integrated approach, explore selected case studies of infection from a body system of origin perspective. You will explore the characteristics of viral, bacterial, fungal and protist pathogens and their virulence mechanisms for establishment and progression of disease. Comprehensive consideration of host immune response and characteristic pathological changes to tissue that arise will then be considered. Upon completion of this unit, you will be able to explain microbial pathogenic processes of infection including: mechanisms for colonisation, invasion and damage to host tissue; the ways in which your immune system recognises and destroys invading microbes; how T cell response is activated and antibodies function. You will learn about pathogenesis, symptoms, current challenges of treatment including antibiotic resistance, control and vaccination strategies. You will develop a holistic perspective of infectious diseases. You will work collaboratively to solve challenging problems in Biomedical Sciences. Practical classes will investigate normal flora, host defences and case studies of medically important microbes with linkage to disease outcome. You will also obtain experience and understanding of modern experimental techniques in microbiology and immunopathology.

MIMI2902 Microbes, Infection and Immunity (Advanced)

Credit points: 6 Teacher/Coordinator: Dr Leona Campbell Session: Semester 2 Classes: Lectures, online lecturettes, discussion forums and self-directed learning activities; Face-to-face seminars, practicals, enquiry- and scenario-based workshops (5 hours per week for 13 weeks). Prerequisites: A mark of 70 or above in (BIOL1XX7 or MBLG1XX1 or BIOL1XX8 or MEDS1X01 or BIOL1XX3) Prohibitions: MEDS2004 or BMED2404 or MIMI2002 or IMMU2101 or MICR2021 or MICR2921 or MICR2022 or MICR2922 or BMED2807 or BMED2808 Assumed knowledge: Human biology (BIOL1XX3 or BIOL1XX8 or MEDS1X01) and biological chemistry (CHEM1XX1 or CHEM1903) Assessment: final examination (40%), mid-semester examination (10%), practical exercises (20%), formative online activities, research publication-based activities (20%), integrated assessment (10%) Mode of delivery: Normal (lecture/lab/tutorial) day

Transmission, pathogenicity and immune response to microbes are key concepts for understanding infectious disease processes. In this unit you will establish a conceptual foundation and, using an integrated approach, explore selected infection case studies from a body system of origin perspective. You will explore characteristics of viral, bacterial, fungal and protist pathogens and their virulence mechanisms for establishment and progression of disease. Comprehensive consideration of host immune response and consequent characteristic pathological changes to tissue will be considered. Upon completion, you will be able to explain microbial pathogenic processes of infection including: mechanisms for colonisation, invasion and damage to host tissue; the ways your immune system recognises and destroys invading microbes; how T cell response is activated and antibodies function. You will learn about pathogenesis, symptoms, current challenges of treatment including antibiotic resistance, control and vaccination strategies. This advanced unit has the same overall structure as MIMI2002 but contains a unique science communication exercise in which you will actively participate in small group sessions and be assessed with a short essay. This advanced component explores how recent advances in microbiology, infection and immunity are communicated to the wider public and is based on recent publications with potential high impact for society.

MEDS coded

MEDS2004 Microbes, Infection and Immunity

Credit points: 6 Teacher/Coordinator: Dr Leona Campbell Session: Semester 2 Classes: Online lecturettes, discussion forums and self-directed learning activities; Face-to-face seminars, practicals, enquiry-, multimedia module- and data analysis-based workshops (5 hours per week for 13 weeks). Prerequisites: BIOL1XX3 or BIOL1XX7 or BIOL1X08 or MEDS1X01 or MBLG1XX1 Prohibitions: MIMI2002 or MIMI2902 or MICR2021 or MICR2921 or MICR2022 or MICR2922 or IMMU2101 or BMED2404 or BMED2807 or BMED2808 Assumed knowledge: Human biology (BIOL1XX3 or BIOL1XX8 or MEDS1X01) and biological chemistry (CHEM1XX1 or CHEM1903) Assessment: final examination (40%), mid-semester examination (10%), practical exercises (20%), online activities (20%), integrated assessment (10%) Mode of delivery: Normal (lecture/lab/tutorial) day

(MEDS coded units of study are only available to students in the Medical Science stream).

Selective

BCMB2001 Biochemistry and Molecular Biology

Credit points: 6 Teacher/Coordinator: Dr Dale Hancock Session: Semester 1 Classes: Three lectures per week; one 4-hour practical and one 1-hour tutorial session per fortnight Prerequisites: 6cp of (BIOL1XX7 or MBLG1XXX) and 6cp of (CHEM1XX1 or CHEM1903) Prohibitions: BCHM2072 or BCHM2972 or MBLG2071 or MBLG2971 or BMED2405 or BCMB2901 or MEDS2003 Assessment: Assignments, skills-based assessment, quizzes, exam Mode of delivery: Normal (lecture/lab/tutorial) day

Without cells, life as we know it would not exist. These dynamic assemblies, packed with biological molecules are constantly in action. But how do cells work? Why is the food that you eat so important for cellular function? How is information transmitted from generation to generation? And, what happens as a result of disease or genetic mutation? In this unit of study you will learn how cells work at the molecular level, with an emphasis on human biochemistry and molecular biology. We will focus initially on cellular metabolism and how cells extract and store energy from fuels like fats and carbohydrates, how the use of fuels is modulated in response to exercise, starvation and disease, and how other key metabolites are processed. Then we will explore how genetic information is regulated in eukaryotes, including replication, transcription and translation, and molecular aspects of the cell cycle, mitosis and meiosis. Our practicals, along with other guided and online learning sessions will introduce you to widely applied and cutting edge tools that are essential for modern biochemistry and molecular biology. By the end of this unit you will be equipped with foundational skills and knowledge to support your studies in the life and medical sciences.

Textbooks

Stryer Biochemistry 8th Edition ISBN-13:978-1-4641-2610-9

BCMB2901 Biochemistry and Molecular Biology (Advanced)

Credit points: 6 Teacher/Coordinator: Dr Dale Hancock Session: Semester 1 Classes: Three lectures per week; one 4-hour practical and one 1-hour tutorial session per fortnight Prerequisites: A mark of at least 70 from (BIOL1XX7 or MBLG1XX1) and (CHEM1XX1 or CHEM1903) Prohibitions: BCHM2072 or BCHM2972 or MBLG2071 or MBLG2971 or BMED2405 or BCMB2001 or MEDS2003 Assessment: Assignments, quiz, skills-based assessment, exam Mode of delivery: Normal (lecture/lab/tutorial) day

Without cells, life as we know it would not exist. These dynamic assemblies, packed with biological molecules are constantly in action. But how do cells work? Why is the food that you eat so important for cellular function? How is information transmitted from generation to generation? And, what happens as a result of disease or genetic mutation? In this unit of study you will learn how cells work at the molecular level, with an emphasis on human biochemistry and molecular biology. We will focus initially on cellular metabolism and how cells extract and store energy from fuels like fats and carbohydrates, how the use of fuels is modulated in response to exercise, starvation and disease, and how other key metabolites are processed. Then we will explore how genetic information is regulated in eukaryotes, including replication, transcription and translation, and molecular aspects of the cell cycle, mitosis and meiosis. The advanced laboratory component will provide students with an authentic research laboratory experience while in the theory component, current research topics will be presented in a problem-based format through dedicated advanced tutorial sessions. This material will be assessed by creative student-centered activities supported by eLearning platforms.

Textbooks

Stryer Biochemistry 8th Edition ISBN-13:978-1-4641-2610-9

IMMU2011 Immunobiology

Credit points: 6 Teacher/Coordinator: Dr Umaimainthan Palendira Session: Semester 1 Classes: Online lecturettes, weekly Interactive lectures, fortnightly Workshops and Practicals. ~4-5h face-to-face per week Prerequisites: BIOL1XX7 or (BIOL1XX8 or BIOL1XX3 or MEDS1X01) or BIOL1XX2 or MBLG1XX1 Prohibitions: IMMU2911 Assumed knowledge: CHEM1XX1 or CHEM1903 Assessment: Online quizzes (15%), practical reports (30%), title and abstract task (15%) and final exam (40%). Mode of delivery: Normal (lecture/lab/tutorial) day

Immunobiology is the study of defence mechanisms that protect living organisms against life-threatening infections. In this unit of study you will explore the essential features of the host immune responses mounted by animals, both vertebrates and invertebrates, plants and microbes themselves. Studies in animal and microbial immunobiology are leading to breakthroughs in veterinary and clinical medicine, including combatting infectious diseases, maximising transplant success, treating allergies, autoimmune diseases and cancer, as well as the development of new vaccines to prevent disease. Understanding the immunobiology of plants also enables us to protect crops from disease which enhances our food security. In this unit of study you will be provided with an overview of immunobiology as a basic research science. We will explore the nature of the immune cells and molecules that recognise danger and how the immune system of animals and plants respond at the cellular and molecular level. Practical and tutorial sessions are designed to illustrate particular concepts introduced in other face-to-face activities. Further self-directed learning activities, including online learning activities, will facilitate integration of fundamental information and help you apply this knowledge to the ways in which the host organism defends against disease. Upon completion, you will have developed the foundations to undertake further studies in Biology, Animal Health, Immunology and Pathology. Ultimately, this could lead you to a career in medical research, biosecurity and/or Veterinary Science.

Textbooks

Abbas, Lichtman and Pillai (2016) Basic Immunology: Functions and Disorders of The Immune System, 5th Edition

IMMU2911 Immunobiology (Advanced)

Credit points: 6 Teacher/Coordinator: Dr Umaimainthan Palendira Session: Semester 1 Classes: Online lecturettes, weekly Interactive lectures, fortnightly Workshops and Practicals . ~4-5h face-to-face per week Prerequisites: A mark of 70 or above in [BIOL1XX7 or (BIOL1XX8 or BIOL1XX3 or MEDS1X01) or BIOL1XX2 or MBLG1XX1] Prohibitions: IMMU2011 Assumed knowledge: CHEM1XX1 or CHEM1903 Assessment: Online quizzes (20%), practical reports (15%), journal article comprehension task (5%), title and abstract written task (10%) and final exam (50%) Mode of delivery: Normal (lecture/lab/tutorial) day

Immunobiology is the study of defence mechanisms that protect living organisms against life-threatening infections. In this unit of study you will explore the essential features of the host immune responses and how it evolved from unicellular organisms to complex multi-cellular organisms. Studies in animal and microbial immunobiology are leading to breakthroughs in veterinary and clinical medicine, including combatting infectious diseases, maximising transplant success, treating allergies, autoimmune diseases and cancer, as well as development of new vaccines to prevent disease. Understanding the immunobiology of plants also enables us to protect crops from disease which enhances our food security. In this unit of study you will be provided with a detailed overview of immunobiology as a basic research science. We will explore in detail the nature of the immune cells and molecules that recognise danger and how the immune system of animals and plants respond at the cellular and molecular level. Advanced practical and tutorial sessions are designed to illustrate particular concepts introduced in other face-to-face activities. Further self-directed learning activities, including online learning activities, will facilitate integration of fundamental information and help you apply this knowledge to the ways in which the host organism defends against disease. This advanced version of Immunobiology has the same overall concepts as the mainstream unit but material is discussed in a manner that offers a greater level of challenge and academic rigour. Students enrolled in the advanced stream will participate in alternative components which may for example include guest lectures from experts. The nature of these components may vary from year to year.

Textbooks

Abbas, Lichtman and Pillai (2016) Basic Immunology: Functions and Disorders of The Immune System, 5th Edition

MEDS2003 Biochemistry and Molecular Biology

Credit points: 6 Teacher/Coordinator: Dr Dale Hancock Session: Semester 1 Classes: Three lectures per week; one 4-hour practical session and 1 h tutorial per fortnight Prerequisites: 6p from (BIOL1XX7 or MBLG1XX1) and 6cp of (CHEM1XX1 or CHEM1903) Prohibitions: BCHM2072 or BCHM2972 or MBLG2071 or MBLG2971 or BMED2405 or BCMB2001 or BCMB2901 or BMED2804 Assessment: Group presentation (5%), In-class continuous assessment (25%), PeerWise MCQ design (10%), ELMA design essay and interpretation (10%), final exam (50%) Mode of delivery: Normal (lecture/lab/tutorial) day

Without cells, life as we know it would not exist. These dynamic assemblies, packed with biological molecules are constantly in action. But how do cells work? Why is the food that you eat so important for cellular function? How is information transmitted from generation to generation? What happens as a result of disease or genetic mutation? In this unit of study you will learn how cells work at the molecular level, with an emphasis on human biochemistry and molecular biology. We will focus initially on cellular metabolism and how cells extract and store energy from fuels like fats and carbohydrates, how fuel use is modulated in response to exercise, starvation and disease, and how other key metabolites are processed. Then we will explore how genetic information is regulated in eukaryotes, including replication, transcription and translation, and molecular aspects of the cell cycle, mitosis and meiosis. Our practicals, along with other guided and online learning sessions will introduce you to widely applied and cutting-edge tools that are essential for modern biochemistry and molecular biology. By the end of this unit you will be equipped with foundational skills and knowledge to support your studies in the medical and life sciences.

Textbooks

Canvas, ELN Peerwise Site, Blackboard LMS Textbook: Biochemistry - Berg, Tymoczko, Gatto, Stryer 8th Ed or higher Wikipedia

(MEDS coded units of study are only available to students in the Medical Science stream).

3000-level units of study

Core

CPAT3201 Pathogenesis of Human Disease 1

Credit points: 6 Teacher/Coordinator: A/Prof Paul Witting Session: Semester 1 Classes: Three 1-hour lectures and one 3-hour research tutorial per week. Prerequisites: 12cp from {[ANAT2008 or ANAT2009 or (ANAT2010 or ANAT2910) or ANAT2011] or [(BCHM2071 or BCHM2971) or (BCHM2072 or BCHM2972)] or [(BCMB2001 or BCMB2901) or (BCMB2002 or BCMB2902)] or [(BIOL2021 or BIOL2921) or (BIOL2022 or BIOL2922) or (BIOL2024 or BIOL2924) or (BIOL2030 or BIOL2930) or (BIOL2031 or BIOL2931)] or [(GEGE2001 or GEGE2901)] or [(IMMU2101 or MICR2021 or MICR2921 or MICR2022 or MICR2922 or MICR2031 or MICR2931 or MIMI2002 or MIMI2902)] or [(MBLG2071 or MBLG2971) or (MBLG2072 or MBLG2972)] or [(PCOL2011 or PCOL2021) or (PCOL2012 or PCOL2022)] or [(PHSI2005 or PHSI2905) or (PHSI2006 or PHSI2906) or (PHSI2007 or PHSI2907) or [PHSI2008 or PHSI2908)] or [(BMED2403 and BMED2404)]} or [MEDS2004 and 6cp from (MEDS2001 or MEDS2002 or MEDS2003 or MEDS2005)] Prohibitions: CPAT3901 Assumed knowledge: Sound knowledge of biology through meeting pre-requisites Assessment: One 2-hour exam (60%), one major research essay (1500w) (20%), two 0.5-hour in-semester exams (20%). Mode of delivery: Normal (lecture/lab/tutorial) day

The Pathogenesis of Human Disease 1 unit of study modules will provide a theoretical background to the scientific basis of the pathogenesis of disease. Areas covered in theoretical modules include: tissue responses to exogenous factors, adaptive responses to foreign agents, cardiovascular/pulmonary/gut responses to disease, forensic science, neuropathology and cancer. The aims of the course are: - To give students an overall understanding of the fundamental biological mechanisms governing disease pathogenesis in human beings. - To introduce to students basic concepts of the pathogenesis, natural history and complications of common human diseases. - To demonstrate and exemplify differences between normality and disease. - To explain cellular aspects of certain pathological processes. Together with CPAT3202, the unit of study would be appropriate for those who intend to proceed to Honours research, to postgraduate studies such as Medicine or to careers in biomedical areas such as hospital science. Enquires should be directed to anthea.matsimanis@sydney.edu.au

Textbooks

Kumar, Abbas and Aster. Robbins Basic Pathology, 9th edition. Saunders. 2012.

CPAT3901 Pathogenesis of Human Disease 1 (Advanced)

Credit points: 6 Teacher/Coordinator: A/Prof Paul Witting Session: Semester 1 Classes: Lectures (2 h/wk) and online lecturettes (3 x 20 min/wk); group focus tutorial (3 x 2 h over 2-3 weeks); guided museum session (1 h/wk); and preparation of online research notebooks (1 h/wk). Prerequisites: A mark of 70 or above in 12cp from {[ANAT2008 or ANAT2009 or (ANAT2010 or ANAT2910) or ANAT2011] or [BCHM2071 or BCHM2971) or BCHM2072 or BCHM2972) or BCHM2081 or BCHM2981) or BCHM2082 or BCHM2982)] or [(BCMB2001 or BCMB2901) or BCMB2002 or BCMB2902)] or [(BIOL2021 or BIOL2921) or (BIOL2022 or BIOL2922) or (BIOL2024 or BIOL2924) or (BIOL2030 or BIOL2930) or (BIOL2031 or BIOL2931)] or [(GEGE2001 or GEGE2901)] or [(IMMU2101 or MICR2021 or MICR2921 or MICR2022 or MICR2922 or MICR2031 or MICR2931 or MIMI2002 or MIMI2902)] or [(MBLG2071 or MBLG2971) or (MBLG2072 or MBLG2972)] or [(PCOL2011 or PCOL2021) or (PCOL2012 or PCOL2022)] or [(PHSI2005 or PHSI2905) or (PHSI2006 or PHSI2906) or (PHSI2007 or PHSI2907) or [PHSI2008 or PHSI2908)] or [(BMED2403 and BMED2404)]} or [MEDS2004 and 6cp from (MEDS2001 or MEDS2002 or MEDS2003 or MEDS2005)] Prohibitions: CPAT3201 Assumed knowledge: A working knowledge of biology Assessment: Week 2 in-semester quiz 1 - 5% (12 MCQ)?Museum tour and report (module 1) - 5%Week 6 in-semester quiz 2 - 5% (12 MCQ)Museum tour and report (module 2) - 5%Week 8 in-semester quiz 3 - 5% (12 MCQ)Museum tour and report (module 3) - 5%Week 9 in-semester quiz 4 - 5% (12 MCQ)Museum tour and report (module 4) - 5% Week 10-12 Group focus learning module that precedes assignment of the pathogenesis essays to each group; students will then work in small groups to build short oral presentations (5 min) on the assigned topics. These presentations will be delivered within the groups and in the presence of a content expert that will provide feed back together with group feed back for each presentation. This will be a formative task.Week 13 Pathogenesis report - 20%Exam period final exam (40%). Mode of delivery: Block mode

Note: Department permission required for enrolment

A deep understanding of pathological mechanisms for disease progression leads to improved human health outcomes. As human populations across the world are ageing, the increasing burden of age-related disease will become one of the greatest challenges facing modern medical science. To equip students with skills appropriate for job-ready careers in the biomedical sciences specialising in pathology it is necessary to provide an integrated understanding of how to evaluate and analyse crucial pathological mechanisms governing disease progression in humans. You will participate in inquiry-led learning modules focused on the systems theory of disease and the underlying mechanisms that promote disease progression in humans. To demonstrate disease you will review high-resolution imagery of pathological specimens using innovative online tools combined with in-depth description of immunological, molecular and biochemical process that underpin the pathogenesis of disease in a range of major body organs. You will undertake investigations to gain an advanced understanding of the health complications of common human diseases. You will learn to use a process of high-level deduction to identify key differences between normality and disease in order to explain cellular aspects of certain pathological processes. Through undertaking this unit you will develop the necessary skill set to define and strategically assess how different organ systems react to injury/insult and how to apply basic concepts of disease processes, which ultimately improve the capacity to manage and intervene in fundamental and clinical aspects of health and disease.

Textbooks

All resources will be made available through the Canvas LMS UoS site and the Pathology museum website. Robbins Basic Pathology; 9th Edition, Eds Kumar, Abbas, Fausto and Mitchell

IMMU3102 Molecular and Cellular Immunology

Credit points: 6 Teacher/Coordinator: A/Prof Carl Feng Session: Semester 1 Classes: Three lectures (1 hour each) will be given each fortnight: 2 lectures in one week and one lecture the following week. Two hour tutorials will run weeks 2 to 7 and four hour practical will run from week 8 to 13. Prerequisites: IMMU2101 or BMED2404 or MEDS2004 or MIMI2X02 or IMMU2X11 Prohibitions: IMMU3902 Assessment: Formal examination (one 2 hour exam) and Progressive assessment including written, practical and oral based assessments (100%). Mode of delivery: Normal (lecture/lab/tutorial) day

Textbooks

Abbas, AK, Lichtman, AH and Pillai, S. Cellular and Molecular Immunology 8th edition. 2015. Elsevier.

IMMU3902 Molecular and Cellular Immunology (Advanced)

Credit points: 6 Teacher/Coordinator: A/Prof Carl Feng Session: Semester 1 Classes: Three lectures (1 hour each) will be given each fortnight: 2 lectures in one week and one lecture the following week. Two hour tutorials will run weeks 2 to 7 and Four hour practical will run from week 8 to 13. Prerequisites: A mark of 70 or above in (IMMU2101 or BMED2404 or MEDS2004 or MIMI2X02 or IMMU2X11) Prohibitions: IMMU3102 Assessment: Formal examination (one 2 hour exam) and Progressive assessment including written, practical and oral based assessments (100%). Mode of delivery: Normal (lecture/lab/tutorial) day

This unit is available to students who have performed well in Introductory Immunology (IMMU2101). Advanced students will complete the same core lecture material as students in IMMU3102 but attend a series of specialized seminar and research based tutorial classes.

Textbooks

Textbooks Abbas, AK, Lichtman, AH and Pillai, S. Cellular and Molecular Immunology 8th edition. 2015. Elsevier.

Selective

CPAT3202 Pathogenesis of Human Disease 2

Credit points: 6 Teacher/Coordinator: Dr Melanie White Session: Semester 2 Classes: Practical Module Prerequisites: 12cp from {[ANAT2008 or ANAT2009 or (ANAT2010 or ANAT2910) or ANAT2011] or [(BCHM2071 or BCHM2971) or (BCHM2072 or BCHM2972)] or [(BCMB2001 or BCMB2901) or (BCMB2002 or BCMB2902)] or [(BIOL2021 or BIOL2921) or (BIOL2022 or BIOL2922) or (BIOL2024 or BIOL2924) or (BIOL2030 or BIOL2930) or (BIOL2031 or BIOL2931)] or [(GEGE2001 or GEGE2901)] or [(IMMU2101 or MICR2021 or MICR2921 or MICR2022 or MICR2922 or MICR2031 or MICR2931 or MIMI2002 or MIMI2902)] or [(MBLG2071 or MBLG2971) or (MBLG2072 or MBLG2972)] or [(PCOL2011 or PCOL2021) or (PCOL2012 or PCOL2022)] or [(PHSI2005 or PHSI2905) or (PHSI2006 or PHSI2906) or (PHSI2007 or PHSI2907) or [PHSI2008 or PHSI2908)] or [(BMED2403 and BMED2404)]} or [MEDS2004 and 6cp from (MEDS2001 or MEDS2002 or MEDS2003 or MEDS2005)] Corequisites: CPAT3201 Prohibitions: CPAT3901 Assumed knowledge: Sound knowledge of biology through meeting pre-requisites Assessment: One 2-hour exam (60%), Museum Practical Reports (40%). Practical field work: One 1.5-hour microscopic practical or one 1-hour museum practical per week (alternating). Mode of delivery: Normal (lecture/lab/tutorial) day

The Pathogenesis of Human Disease 2 unit of study modules will provide a practical background to the scientific basis of the pathogenesis of disease. Areas covered in practical modules include disease specimen evaluation on a macroscopic and microscopic basis. The aims of the course are: - To enable students to gain an understanding of how different organ systems react to injury and to apply basic concepts of disease processes. - To equip students with skills appropriate for careers in the biomedical sciences and for further training in research or professional degrees. At the end of the course students will: - Have acquired practical skills in the use of a light microscope. - Have an understanding of basic investigative techniques for disease detection in pathology. - Be able to evaluate diseased tissue at the macroscopic and microscopic level. - Have the ability to describe, synthesise and present information on disease pathogenesis. - Transfer problem-solving skills to novel situations related to disease pathogenesis. This unit of study would be appropriate for those who intend to proceed to Honours research, to postgraduate studies such as Medicine or to careers in biomedical areas such as hospital science. Enquiries should be directed to anthea.matsimanis@sydney.edu.au.

Textbooks

Kumar, Abbas and Aster. Robbins Basic Pathology, 9th edition. Saunders. 2012.

CPAT3902 Pathogenesis of Human Disease 2 (Advanced)

Credit points: 6 Teacher/Coordinator: Dr Melanie White Session: Semester 2 Classes: lectures (2 h/wk); microscopy tutorial (1.5 h); guided museum session (1 h/wk); and group focus tutorial (1.5 h/wk) Prerequisites: A mark of 70 or above in 12cp from {[ANAT2008 or ANAT2009 or (ANAT2010 or ANAT2910) or ANAT2011] or [BCHM2071 or BCHM2971) or BCHM2072 or BCHM2972) or BCHM2081 or BCHM2981) or BCHM2082 or BCHM2982)] or [(BCMB2001 or BCMB2901) or BCMB2002 or BCMB2902)] or [(BIOL2021 or BIOL2921) or (BIOL2022 or BIOL2922) or (BIOL2024 or BIOL2924) or (BIOL2030 or BIOL2930) or (BIOL2031 or BIOL2931)] or [(GEGE2001 or GEGE2901)] or [(IMMU2101 or MICR2021 or MICR2921 or MICR2022 or MICR2922 or MICR2031 or MICR2931 or MIMI2002 or MIMI2902)] or [(MBLG2071 or MBLG2971) or (MBLG2072 or MBLG2972)] or [(PCOL2011 or PCOL2021) or (PCOL2012 or PCOL2022)] or [(PHSI2005 or PHSI2905) or (PHSI2006 or PHSI2906) or (PHSI2007 or PHSI2907) or [PHSI2008 or PHSI2908)] or [(BMED2403 and BMED2404)]} or [MEDS2004 and 6cp from (MEDS2001 or MEDS2002 or MEDS2003 or MEDS2005)] Prohibitions: CPAT3202 Assumed knowledge: A working knowledge of biology Assessment: Week 2 pre-quiz 1 - 5% (10 MCQ)?Week 4 pre-quiz 2 - 5% (10 MCQ)Week 6 Electronic notebook 1 - 10% (Narrative Plan document that is to be populated with data obtained by the student)?Week 8 pre-quiz 3 - 5% (10 MCQ)Week 10 pre-quiz 4 - 5% (10 MCQ)Week 12 Electronic notebook 1 - 10% (Narrative Plan document that is to be populated with data obtained by the student)?Week 13 or 14 Practical exam - 20% (Specimen and micrograph-based practical exam) followed by final exam (40%). Practical field work: One 1.5-hour microscopic practical or one 1-hour museum practical per week (alternating) Mode of delivery: Normal (lecture/lab/tutorial) day

Note: Department permission required for enrolment

Understanding the underlying mechanisms of disease and disease progression, improving human health and addressing the impact of human activity on individual health outcomes are some of the great challenges facing modern medical sciences in the 21st century. To equip students with skills appropriate for careers in the biomedical sciences and for further training in research or professional degrees it is necessary to provide an integrated understanding of how to evaluate and analyse crucial pathological mechanisms governing disease progression in humans. You will participate in inquiry-led museum and practical class sessions that review human pathological specimens using innovative online tools combined with high-resolution microscopy to crystallise and reinforce concepts developed in the unit. You will undertake investigations to gain an advanced understanding of the pathogenesis, natural history and related health complications of common human diseases. You will learn to use methodologies to exemplify key differences between normality and disease in order to explain cellular aspects of certain pathological processes. Through undertaking this unit you will develop the necessary practical skills required to employ advanced imaging technologies that are increasingly used to define and strategically assess how different organ systems react to injury/insult, which ultimately improve the capacity to manage and intervene in fundamental and clinical aspects of health and disease.

Textbooks

All resources will be made available through the Canvas LMS UoS site; through electronic notebooks and the Pathology museum website. Robbins Basic Pathology; 9th Edition, Eds Kumar, Abbas, Fausto and Mitchell

IMMU3202 Immunology in Human Disease

Credit points: 6 Teacher/Coordinator: A/Prof Allison Abendroth Session: Semester 2 Classes: Three 1 hour lectures, one tutorial and one 4 hour practical per fortnight. Prerequisites: IMMU2101 or BMED2404 or MEDS2004 or MIMI2X02 or IMMU2X11 Prohibitions: IMMU3903 Assessment: Formal examination (one 2 hour exam) and Progressive assessment including written, practical and oral based assessments (100%). Mode of delivery: Normal (lecture/lab/tutorial) day

This study unit builds on the series of lectures that outlined the general properties of the immune system, effector lymphocytes and their functions, delivered in the core courses, IMMU2101 - Introductory Immunology and BMED2404 - Microbes, Infection and Immunity (formerly IMMU2001 and BMED2807). We emphasise fundamental concepts to provide a scientific basis for studies in clinical immunology; dysfunctions of the immune system e.g. autoimmune disease, immunodeficiencies, and allergy, and immunity in terms of host - pathogen interactions. This unit has a strong focus on significant clinical problems in immunology and the scientific background to these problems. The unit includes lectures from research scientists and clinicians covering areas such as allergy, immunodeficiency, autoimmune disease and transplantation. This course provides challenging information from the forefront of clinical immunology and helps the student develop an understanding of immune responses in human health and disease. Three lectures (1 hour each) will be given each fortnight: 2 lectures in one week and one lecture the following week, for the duration of the course. This unit directly complements the unit 'Molecular and Cellular Immunology IMMU3102' and students are very strongly advised to undertake these study units concurrently.

Textbooks

Abbas, AK, Lichtman, AH and Pillai, S. Cellular and Molecular Immunology 8th edition. 2015. Elsevier

IMMU3903 Immunology in Human Disease (Advanced)

Credit points: 6 Teacher/Coordinator: A/Prof Allison Abendroth Session: Semester 2 Classes: 3 lectures,1 seminar/tutorial (2 hours) and1 practical (4 hours) every 2 weeks. Prerequisites: A mark of 70 or above in (IMMU2101 or BMED2404 or MEDS2004 or MIMI2X02 or IMMU2X11) Prohibitions: IMMU3202 Assessment: Formal examination (one 2 hour exam) and Progressive assessment including written, practical and oral based assessments (100%). Mode of delivery: Normal (lecture/lab/tutorial) day

This unit is available to students who have performed well in Introductory Immunology (IMMU2101). Advanced students will complete the same core lecture material as students in IMMU3202 but carry out advanced level practical work and a series of specialized seminar based tutorial classes.

Textbooks

Abbas, AK, Lichtman, AH and Pillai, S. Cellular and Molecular Immunology 8th edition. 2015. Elsevier

Interdisciplinary Project

IMPA3888 Immunopathology Interdisciplinary Project

Credit points: 6 Teacher/Coordinator: Dr Megan Steain Session: Semester 2 Classes: online lecturettes, interactive lectures and project-based workshops Prerequisites: MEDS2004 or MIMI2X02 or IMMU2101 or BMED2404 or IMMU2X11 Assumed knowledge: Fundamental cellular and molecular immunology and pathology as taught in IMMU3102 and CPAT3201 Assessment: Online quiz (10%), Reflective task (10%), Peer Review (10%), Project report (draft 5%/ final report 15%), Group project presentation (10%), Final exam (40%) Mode of delivery: Normal (lecture/lab/tutorial) day

Solutions to wicked health problems like multiple sclerosis, diabetes, tuberculosis and cancer will require an interdisciplinary approach. The study of Immunology and Pathology is underpinned by their core discipline strengths in clinical science and the underlying pathogenesis of human disease. In this unit, you will draw on these discipline strengths and apply them in an interdisciplinary context. For example, you and your team might be challenged to come up with a strategy to raise immunisation rates. Success in this endeavour will require you to continue to explore your discipline knowledge, while also meeting and collaborating with students from across the University through project-based learning; identifying and solving problems, collecting and analysing data and communicating your findings to a diverse audience. In so doing, you will have fostered the ability to work in interdisciplinary teams, which is essential for future professional and research pathways in Immunology and Pathology.

Textbooks

Learning resources will be available via the course Canvas site. Recommended Textbooks: 1. Abbas, Lichtman and Pillai. Cellular and Molecular Immunology. 9th Edition. 2017. 2. Kumar, Abbas and Aster. Robbins Basic Pathology, 9th edition. 2012.

SCPU3001 Science Interdisciplinary Project

Credit points: 6 Teacher/Coordinator: Prof Pauline Ross Session: Intensive February,Intensive July,Semester 1,Semester 2 Classes: The unit consists of one seminar/workshop per week with accompanying online materials and a project to be determined in consultation with the partner organisation and completed as part of a team with academic supervision. Prerequisites: Completion of 2000-level units required for at least one Science major. Assessment: group plan, group presentation, reflective journal, group project Mode of delivery: Normal (lecture/lab/tutorial) day

This unit is designed for students who are concurrently enrolled in at least one 3000-level Science Table A unit of study to undertake a project that allows them to work with one of the University's industry and community partners. Students will work in teams on a real-world problem provided by the partner. This experience will allow students to apply their academic skills and disciplinary knowledge to a real-world issue in an authentic and meaningful way. Participation in this unit will require students to submit an application to the Faculty of Science.

University of Sydney Handbooks - 2020 Archive

The University of Sydney - Interdisciplinary Studies Handbook 2020

Immunology and Pathology Descriptions