University of Sydney Handbooks - 2011 Archive

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Sleep Medicine

Graduate Diploma in Sleep Medicine

(GradDipSleep) KF067

Master of Medicine (Sleep Medicine)

(MMed(Sleep Medicine)) KC041

Master of Science in Medicine (Sleep Medicine)

(MScMed(Sleep Medicine)) KC042

Course Credit
points for award
Duration
GradDipSleep 48 2 to 3 years
MMed(Sleep Medicine) 60 3 to 6 years
MScMed(Sleep Medicine) 60 3 to 6 years
Overview

Sleep medicine has evolved to something of a sub-specialty area with relevance across a number of fields, including respiratory medicine, cardiology, neurology, surgery and dentistry, with wider implications for health sciences and public health.

The program aims to provide up-to-date information on theory and practice of sleep medicine through distance education; the courses provide training in clinical, theoretical and research techniques in the field of sleep medicine and help to establish criteria for best practice in the field. These courses are suitable for those already working in the area of sleep medicine, or for those wishing to undertake a career change. The courses provide a firm basis for vocational training in this discipline.

The Master of Medicine (Sleep Medicine) and the Master of Science in Medicine (Sleep Medicine) are essentially the same program with different admission requirements. Only medical graduates (ie those with an MBBS) may be admitted to the Master of Medicine while non-medical graduates may be admitted to the Master of Science in Medicine. Students follow the same program of study, with the only difference being the title of the course they are awarded on completion. Students enrolled in the Graduate Diploma in Sleep Medicine or either of the Masters programs complete the same units of study for the first 4 semesters. Masters students then proceed (with Departmental permission) to a research project culminating in the submission of a treatise.

Course Outcomes

These courses provide students with the opportunity to gain an excellent understanding of the theoretical and practical aspects of sleep medicine. As sleep medicine is relevant to so many areas of medicine and health care, it enables students to competently incorporate the new skills into their current practice. The courses also equip students with the skills to undertake research in this growing area of medicine.

Further Information

The program is taught predominantly via the internet. Enrolled students are provided with a user name and password that allows them to access a protected course website. Coursework units of study are delivered as online tutorials and self-directed learning tasks. In some units of study, candidates are required to make formal presentations and analyse case-studies.

Internet conferencing technology ensures that students maintain regular contact with staff. The coursework in the first three semesters consists of core subjects. The fourth semester includes both core and elective subjects, with students able to take either the adult or paediatric stream.

Students have the option of attending a one-week residential program in late November to early December of each of the first two years of enrolment. The practicum introduces candidates to the technical aspects of sleep medicine and is the time during which students will have the opportunity to discuss the research project that they will complete if they are completing the Master€™s degree.

It is also an excellent opportunity for students that are not involved in sleep medicine on a day-to-day basis to gain valuable practical experience. The residential school is recommended but is no longer an essential component of the course.

Assessment is by formal examination (which is administered via the internet), assignments and presentations.

The treatise unit of study is normally a small research project that is designed and carried out by the student in their place of work in consultation with staff from the sleep medicine course. The resultant treatise is a body of work that generally is in the order of 20,000 words, with the following sections: introduction/literature review, methods, results, discussion/conclusion.

Degree Resolutions

Sydney Medical School resolutions and the printed handbook are the official statement of Faculty policy. The resolutions contained in the printed handbook are accurate as at November 2010. If a conflict is perceived between the content of the printed handbook and information available elsewhere, Sydney Medical School resolutions and the information available in the handbook online shall always take precedence. See the handbook online website:
http://sydney.edu.au/handbooks/handbooks_admin/medicine.shtml.
See the Policy Online website: http://sydney.edu.au/policy, for copies of University policies.

 

Graduate Diploma in Sleep Medicine

Master of Science in Medicine (Sleep Medicine)

Master of Medicine (Sleep Medicine)


These resolutions must be read in conjunction with applicable University By-laws, Rules and policies including (but not limited to) the University of Sydney (Coursework) Rule 2000 (the 'Coursework Rule'), the Resolutions of the Faculty, the University of Sydney (Student Appeals against Academic Decisions) Rule 2006 (as amended) and the Academic Board policies on Academic Dishonesty and Plagiarism.

Course resolutions

1 Course codes

Code Course and stream title
KF067
Graduate Diploma in Sleep Medicine
KC041 Master of Medicine (Sleep Medicine)
KC042 Master of Science in Medicine (Sleep Medicine)

2 Attendance pattern

The attendance pattern for this course is part time only.

3 Master's type

The master's degrees in these resolutions are professional master's courses, as defined by the Coursework Rule.

4 Embedded courses in this sequence

(1)
The embedded courses in this sequence are:
(a)
the Graduate Diploma in Sleep Medicine
(b)
the Master of Medicine (Sleep Medicine)
(c)
the Master of Science in Medicine (Sleep Medicine).
(2)
Providing candidates satisfy the admission requirements for each stage, a candidate may progress to the award of any of the courses in this sequence. Only the longest award completed will be conferred.

5 Admission to candidature

(1)
Available places will be offered to qualified applicants according to the following admissions criteria. In exceptional circumstances the Dean may admit applicants without these qualifications who, in the opinion of the Faculty, have qualifications, evidence of experience and achievement sufficient to successfully undertake the award.
(2)
Admission to the Graduate Diploma in Sleep Medicine requires:
(a)
a Bachelor of Medicine and Bachelor of Surgery of the University of Sydney or equivalent qualification;
or
a bachelor's degree with first or second class honours from the University of Sydney or equivalent qualification, in an appropriate discipline such as biology or health sciences;
or
a bachelor's degree without first or second class honours from the University of Sydney or equivalent qualification, in an appropriate discipline such as biology or health sciences. Applicants must have completed work equivalent to a first or second class honours bachelor's degree.
(b)
one year postgraduate experience in the field of sleep medicine; and
(c)
the applicant to pass a preliminary examination(s) as prescribed by the Faculty.
(3)
Admission to the Master of Medicine (Sleep Medicine) requires:
(a)
a Bachelor of Medicine and Bachelor of Surgery of the University of Sydney or equivalent qualification;
(b)
one year postgraduate experience in the field of sleep medicine; and
(c)
the applicant to pass a preliminary examination(s) as prescribed by the Faculty.
(4)
Admission to the Master of Science in Medicine (Sleep Medicine) requires:
(a)
a bachelor's degree with first or second class honours from the University of Sydney or equivalent qualification;
or
a bachelor's degree without first or second class honours from the University of Sydney or equivalent qualification. Applicants must have completed work equivalent to a first or second class honours bachelor's degree.
(b)
one year postgraduate experience in the field of sleep medicine; and
(c)
the applicant to pass a preliminary examination(s) as prescribed by the Faculty.

6 Requirements for award

(1)
The units of study that may be taken for the course are set out in the Table of Units of Study: Sleep Medicine.
(2)
To qualify for the award of the Graduate Diploma in Sleep Medicine a candidate must successfully complete 48 credit points, including:
(a)
46 credit points of core units of study; and
(b)
2 credit points of elective units of study.
(3)
To qualify for the award of the Master of Medicine (Sleep Medicine) or Master of Science in Medicine (Sleep Medicine) a candidate must successfully complete 60 credit points, including:
(a)
58 credit points of core units of study; and
(b)
2 credit points of elective units of study.

7 Transitional provisions

(1)
These resolutions apply to persons who commenced their candidature after 1 January, 2011 and persons who commenced their candidature prior to 1 January, 2011 who formally elect to proceed under these resolutions.
(2)
Candidates who commenced prior to 1 January, 2011 complete the requirements in accordance with the resolutions in force at the time of their commencement.

Table of Units of Study: Sleep Medicine

Unit of study Credit points A: Assumed knowledge P: Prerequisites C: Corequisites N: Prohibition Session

Core units

SLEE5001
Introductory Sleep Science
1      Semester 1
Semester 2
SLEE5002
History of Sleep Research
1      Semester 1
Semester 2
SLEE5003
Introduction to Sleep Disorders
4      Semester 1
Semester 2
SLEE5005
Research & Literature Searching in Sleep
2      Semester 1
Semester 2
SLEE5006
Physiology of Sleep
4      Semester 1
Semester 2
SLEE5007
Chronobiology
2      Semester 1
Semester 2
SLEE5008
Sleep and Breathing I
2      Semester 1
Semester 2
SLEE5009
Sleep and the Endocrine System
2      Semester 1
Semester 2
SLEE5010
Neuropharmacology of Sleep I
1      Semester 1
Semester 2
SLEE5011
Sleep and the Mind I
2      Semester 1
Semester 2
SLEE5012
Practicum I
5    P SLEE5003 and SLEE5005
Semester 1
Semester 2
SLEE5013
Non-Respiratory Sleep Disorders
2    P SLEE5003
Semester 1
Semester 2
SLEE5014
Sleep and Breathing II
4    P SLEE5003 and SLEE5008
Semester 1
Semester 2
SLEE5015
Neuropharmacology of Sleep II
2    P SLEE5010
Semester 1
Semester 2
SLEE5016
Sleep and the Mind II
1    P SLEE5011
Semester 1
Semester 2
SLEE5017
Sleep and Body Function
2      Semester 1
Semester 2
SLEE5020
Sleep and Breathing III
2    P SLEE5014
Semester 1
Semester 2
SLEE5021
Neuropharmacology of Sleep III
2    P SLEE5015
Semester 1
Semester 2
SLEE5024
Practicum II
5    P SLEE5003 and SLEE5005 and SLEE5012
Semester 1
Semester 2

Additional Core units of study for the master's degree

Master’s degree students must enrol in either SLEE5025 or both SLEE5027 and SLEE5028. A student must be enrolled in order to submit the treatise. If a student is not able to submit his/her treatise after enrolling in 12CP of treatise units, he/she must either re-enrol in SLEE5025 or one of SLEE5027 or SLEE5028, with the concomitant financial liability, every semester until he/she submits.
SLEE5025
Treatise
12    N SLEE5027, SLEE5028

Note: Department permission required for enrolment
Students are required to seek permission from the course coordinator in order to enrol in this unit. If permission is given the coordinator emails the Postgraduate Student Administration Unit asking that the student be enrolled.
Semester 1
Semester 2
SLEE5027
Treatise A
6    N SLEE5025

Note: Department permission required for enrolment
Students are required to seek permission from the course coordinator in order to enrol in this unit. If permission is given the coordinator emails the Postgraduate Student Administration Unit asking that the student be enrolled.
S2 Late Int
Semester 1
Semester 2
SLEE5028
Treatise B
6    N SLEE5025

Note: Department permission required for enrolment
Students are required to seek permission from the course coordinator in order to enrol in this unit. If permission is given the coordinator emails the Postgraduate Student Administration Unit asking that the student be enrolled.
S2 Late Int
Semester 1
Semester 2

Elective Units

SLEE5019
Sleep in Development (Child)
2      Semester 1
Semester 2
SLEE5023
Sleep in Development (Adult)
2      Semester 1
Semester 2
Further enquiries

Mark Norman
Phone: +61 2 9515 7311
Fax: +61 2 9550 3851
Email:

Units of Study Descriptions for 2011

SLEE5001 Introductory Sleep Science

Credit points: 1 Teacher/Coordinator: Professor Colin Sullivan Session: Semester 1,Semester 2 Classes: ~3.5 hours online lectures over 1 semester plus directed reading and independent study Assessment: 1xonline quiz (50%), 1xexam (50%) Campus: Camperdown/Darlington Mode of delivery: On-line
Aims: To become conversant with terminology and basic concepts within the field of sleep medicine and sleep science. Content: Sleep as an Active Process: In contradistinction to common perception, sleep does not involve so much the switching off of neural systems, but the activation of certain areas within the brain, situated in structures such as the medulla, thalamus and basal forebrain. This module introduces basic neural anatomy and physiology necessary for the understanding of the process of sleep. Basic Respiratory Physiology: Understanding mechanisms underlying the maintenance of adequate gas exchange is essential to the study of sleep science and medicine. This module is a short introductory review of respiratory physiology as it relates to sleep medicine.
SLEE5002 History of Sleep Research

Credit points: 1 Teacher/Coordinator: Professor Colin Sullivan Session: Semester 1,Semester 2 Classes: ~3 hours online lectures over 1 semester plus directed reading and independent study Assessment: 1xonline quiz (50%), 1xexam (50%) Campus: Camperdown/Darlington Mode of delivery: On-line
Aims: To understand the milestones that shaped our understanding of the nature of sleep; to understand the development of the concepts of sleep stages, chronobiology and the concept that sleep is not a steady state cycle, but changes through the night; to appreciate importance of polysomnography and the all-night sleep study. Content: Development of Sleep Research: The importance of sleep has been recognized throughout history. However, until recent times sleep was thought to be the intermediate state between wakefulness and death. This section elucidates the observations that have lead to the modern concept of an active dynamic condition we call sleep - from the observation of biological cycles, through the discovery of REM sleep, to the all-night sleep study. Introduction to Methods in Sleep Research: Sleep research involves the use of specific equipment and techniques. The early reports of sleep were confined to case histories and, later, short-term samples of biophysical recording were made. However, it was not until the early 1950s that researchers began to undertake all-night recordings and so polysomnography was born. Polysomnography and the meaning of the biophysical measurements made during full sleep studies will be introduced. In addition, the concepts of sleep stages and the normal changes of cardiorespiratory control and EEG will be introduced.
SLEE5003 Introduction to Sleep Disorders

Credit points: 4 Teacher/Coordinator: Professor Colin Sullivan Session: Semester 1,Semester 2 Classes: ~5 hours online lectures over 1 semester plus directed reading and independent study Assessment: 1xonline quiz (40%), 1xexam (60%) Campus: Camperdown/Darlington Mode of delivery: On-line
Aims: To understand the nature of sleep and gain an overview of normal sleep; to appreciate the changes in sleep associated with aging; to recognize various stages of sleep on a polysomnograph (this will be introduced in this unit, but extended significantly later in the course); to understand the range of sleep disorders, their presentation and diagnosis, including respiratory disturbances (OSA, central apnoea, pulmonary disease), sleep deprivation and fragmentation and general medical disorders which impact on sleep; to understand the epidemiology of sleep disorders and their impact on public health.
Content: Normal Sleep: This module will explain the definitions of sleep states and describe the progression of sleep through the night. The cyclic nature of sleep in humans and animals will be examined with some discussion of factors that affect sleep architecture, including age and drugs.
Introduction to Sleep Stage Scoring: This module will define the various stages of sleep from a practical standpoint, based on polysomnograph records. Candidates will be introduced to the standard methods of scoring sleep states which will be expanded during the practicum. Normal sleep and its variations will be the primary focus, with some discussion on the effects of drugs.
Respiratory Disturbances and Sleep: Respiratory sleep disturbance has a long history of comment in the literature generally, whereas, understanding of the medical significance of this has been a relatively recent phenomenon. This module will present an overview of the types of respiratory disturbances associated with sleep and the clinical presentation and evaluation of these. The natural history of sleep disordered breathing changes during the human lifestyle and the concept of a developmental path for sleep apnoea will be discussed.
Obstructive Sleep Apnoea: OSA has arguably been the most obvious type of sleep disordered breathing throughout history. Severe OSA is a major impediment to quality of life and is potentially life-threatening, not only as cause of impairment of day-time function, but as a predisposing factor to cardiovascular disease and stroke. OSA will be discussed in terms of its occurrence and polysomnographic identification. Reference will be made to OSA throughout life and treatments, however, these will dealt with in more detail in the Sleep and Breathing Units I,II & III.
Central Apnoea: The occurrence and identification of central apnoea will be introduced. This module will give an overview of the range of this phenomenon from apnoea of infancy to Cheyne-Stokes respiration.
Introduction to Respiratory Scoring: This module will introduce respiratory scoring, which is very often a major part of scoring a polysomnographic study. It will define the guidlines used to identify and mark respiratory events throughout a polysomnographic study using the recommendations taken from the Report of The Academy of Sleep Medicine Task Force. The types of devices used to measure respiratory variables will also be discussed.
The Importance of Sleep: The importance of sleep in the maintenance of physical and psychological wellbeing will be covered.
SLEE5005 Research & Literature Searching in Sleep

Credit points: 2 Teacher/Coordinator: Professor Colin Sullivan Session: Semester 1,Semester 2 Classes: ~3.5 hours online lectures over 1 semester plus directed reading and independent study Assessment: 1xshort answer question assignment (30%), 1xonline quiz (30%), 1xexam (40%) Campus: Camperdown/Darlington Mode of delivery: On-line
Aims: To be familiar with the resources of the Medical Library; to be able to conduct an online literature searches and download the results into bibliographic software; to be able to develop a research plan, including hypothesis development and the choice of appropriate methods; to be able to choose the appropriate statistical methods for analysis and read research literature critically.
Content: The Medical Library: In this module the online resources of the Medical Library of the University of Sydney will be utilised and candidates will be able to use their UniKey account to access on-line tutorials, journal articles, catalogues, Medline and other databases for retrieval of information.
Applied Literature Searching: Candidates will be required to choose a topic for a short review (2,000 words), and demonstrate the ability to search for references and utilize bibliographic software for the management of those references. Instruction in the use of suitable bibliographic software integrated with a word processor, will be included in this module. Study Design: In this module you will learn about different types of basic, clinical and epidemiological study designs, which may be implemented to answer a research question relating to sleep and/or sleep disorders. You will be introduced to the concept of blinding of subjects and/or researchers, crossover study designs, and the use of placebo controlled study designs. This module will be useful in assisting those enrolled in the Masters Course to decide on a study they intend to implement for their treatise.
Introduction to Statistical Methods: This module will provide a practical overview of some of the statistical tests and ways of presenting data used in various aspects of biological research, including: student t-test; c 2 test; ANOVA; a priori and post hoc testing; standard deviation; standard error of the mean; confidence intervals; significance; and the differences between types of studies, such as case-controlled, double-blind or meta studies. Particular emphasis will be placed on the choice of appropriate tests for different types of data.
Treatise Development: Candidates will, with guidance choose a topic for research and develop a research plan. The plan will include a review of the background, the hypothesis and methods to be used, including the data analysis. This will be presented as a poster and talk at a mini-conference held during the practicum. This module will be completed over the course of the first year of study, however, the research plan will not be, necessarily, that undertaken for the completion of the candidate's treatise.
Seminar Presentation Skills: In this module you will learn how to prepare a seminar presentation, including the order of presentation, suggested software packages, and suggested colour schemes. You will learn how to effectively present data to a group of peers, including strategies to maximize audience interest. Effectively answering questions at the conclusion of your presentation will also be discussed.
SLEE5006 Physiology of Sleep

Credit points: 4 Teacher/Coordinator: Professor Colin Sullivan Session: Semester 1,Semester 2 Classes: ~2 hours online lectures over 1 semester plus directed reading and independent study Assessment: 1x1500 word essay (30%), 1xonline quiz (20%), 1xexam (50%) Campus: Camperdown/Darlington Mode of delivery: On-line
Aims: To understand cardiorespiratory control as it relates to sleep; to recognize the physiological mechanisms underlying the characteristic EEG of different sleep stages; to understand how motor control changes during the sleep cycle and the importance of this in regulation of sleep; to understand the regulation of homeostasis during sleep.
Content: Respiratory Control I: Review of respiratory control mechanisms and neuroanatomy. Central circuits involved in respiratory control and changes in the modulation of these central control mechanisms during the sleep cycle. Respiratory Control II:Control of ventilation alters during sleep. Responses to hypoxia and hypercapnia will be discussed. In addition, the pattern of respiration during the sleep cycle and the influence of altered arousal and muscle tone on this system will be included in this module. Cardiovascular Control I: Central and autonomic regulation of cardiovascular function during the sleep cycle. Sleep-dependent changes in cerebral and peripheral circulation. Cardiovascular Control II: Integration of cardiovascular and respiratory control mechanisms. The peripheral chemoreceptor and baroreceptor mechanisms. Brain Electrical Activity: Characteristics of EEG and EOG in REM and NREM sleep and wakefulness. Cellular origins of EEG signals. Low frequency oscillations of corticothalamic origin during NREM - spindle, delta and slow waves. Brainstem and thalamic circuits involved in arousal and REM. The Brainstem and REM Sleep: This module describes the ontogeny of REM sleep and the brainstem sites of generation.
Motor Control During Sleep: During the sleep cycle, somatic muscle activity is reduced during NREM and centrally inhibited during REM. The process underlying these changes are complex and will be introduced in this module.
Physiological Function During Sleep: Homeostatic mechanisms during sleep including control of temperature regulation and metabolism.
SLEE5007 Chronobiology

Credit points: 2 Teacher/Coordinator: Professor Colin Sullivan Session: Semester 1,Semester 2 Classes: ~3 hours online lectures over 1 semester plus directed reading and independent study Assessment: 1xonline quiz (40%), 1xexam (60%) Campus: Camperdown/Darlington Mode of delivery: On-line
Aims: To understand the presence and physiological basis of biological rhythms and the ramifications for the sleep-wake cycle; to understand the normal modulation of circadian cycles and the effects when these are disrupted. Content: Chronobiology: The circadian rhythm and its relationship to the sleep cycle is examined along with the concepts of photic and nonphotic zeitgebers. Neural basis of Circadian Rhythm. The neurophysiology of the pacemaker in the suprachiasmatic nucleus and the neural circuits modulating its function. The genetic basis of circadian rhythm generation will also be discussed. Effects of Circadian Rhythms on Physiology I: The internal sleep structure is governed by circadian rhythms and these rhythms also impact upon levels of alertness and cognitive performance. This module deals with this topic and the ramifications for general day-time performance and quality of life if these rhythms are disrupted such as with sleep fragmentation or jet lag. Effects of Circadian Rhythms on Physiology II: This module continues the themes of 2.1.3 and considers the effects of such things as sleep deprivation and shift work on homeostasis and sleep regulation. In addition, the physiological effects and role of chronobiotic agent such as melatonin will be introduced. Circadian Rhythms and Ageing: The timing of sleep wake cycles is controlled by at least two neural clocks in the brain. Throughout the animal world there are numerous examples of cellular clocks, with the sleep wake cycle being the most visible example. Sleep wake patterns and rhythms change with age with alterations in both timing and content of sleep. This module introduces the area of chronobiology and the changes in sleep wake patterns with ageing. Importance of Sleep: Sleep occupies about one third of life and there is clear evidence of its importance for the wellbeing and proper function of many animals. This module provides an introduction to the evidence for the key role of sleep in growth, development and brain function.
SLEE5008 Sleep and Breathing I

Credit points: 2 Teacher/Coordinator: Professor Colin Sullivan Session: Semester 1,Semester 2 Classes: ~2 hours online lectures over 1 semester plus directed reading and independent study Assessment: 1xonline quiz (40%), 1xexam (60%) Campus: Camperdown/Darlington Mode of delivery: On-line
Aims: To understand the way the control of ventilation is affected by the normal sleep cycle; to understand the relationship between the anatomy and physiology of the airways and the mechanics of ventilation during sleep; to introduce the physiological basis for pathologies of ventilation during sleep, especially OSA and central apnoeas. Content: Breathing During Sleep: The changes in spontaneous breathing during sleep and how this differs between REM and NREM sleep are reviewed. The mechanisms underlying these changes are also discussed. Anatomy and Physiology of the Upper Airway During Sleep: The upper airway and in particular the pharynx is particularly involved in the pathogenesis of OSA. The anatomy of the area and the control of muscles that are important for maintenance of airway patency are reviewed in this module. Snoring & Obstructive Sleep Apnoea-Hypopnoea: In this section, the physiology of snoring and OSA will be discussed in terms of its physiological determinants, occurrence and polysomnographic identification. The treatment of these conditions will be introduced. Central Apnoea: The physiology, occurrence and identification of central apnoea will be discussed with the clinical significance.
SLEE5009 Sleep and the Endocrine System

Credit points: 2 Teacher/Coordinator: Professor Colin Sullivan Session: Semester 1,Semester 2 Classes: ~0.5 hours online lectures over 1 semester plus directed reading and independent study Assessment: 1x2000word essay (40%), 1xonline quiz (30%), 1xexam (30%) Campus: Camperdown/Darlington Mode of delivery: On-line
Aims: To understand the specific role of hormones in modulating circadian rhythms and sleep architecture; to appreciate the direct and indirect effects of disorders in hormone systems on sleep. Content: Melatonin & the Pineal: The anatomy and physiology of the pineal and its role in sensing photoperiod. Melatonin as a chronobiotic and its role in normal function and possible therapeutics. Sleep and the Menstrual Cycle: The influence of female sex hormone levels on sleep architecture during the menstrual cycle. Some reference to menopause will be made, however, this will be dealt with in future modules. Sex Hormones & Corticosteroid Disorders: The influence of male sex hormones and imbalances of steroids such as in Cushing's diseases which may have direct or indirect effects on sleep. Management of such conditions is discussed in relation to sleep. Acromegaly, Hypothyriodism and Diabetes: These hormonal imbalances lead to pathophysiological changes that adversely affect sleep. This module examines these changes and management of such patients.
SLEE5010 Neuropharmacology of Sleep I

Credit points: 1 Teacher/Coordinator: Professor Colin Sullivan Session: Semester 1,Semester 2 Classes: ~1 hour online lectures over 1 semester plus directed reading and independent study Assessment: 1xonline quiz (60%), 1xexam (40%) Campus: Camperdown/Darlington Mode of delivery: On-line
Aim: To gain knowledge of the neurotransmitter systems and pharmacology involved in control of sleep and circadian rhythms. Content: Neurotransmitter Systems in Sleep: In order to understand the conditions and treatments for a range of sleep disorders and parasomnias, the neuropharmacology must be understood. These sections discuss sleep mechanisms from the perspective of neurotransmitters and neuromodulators. Some basic physiology will be included for background. Neurotransmitter Systems in Arousal.
SLEE5011 Sleep and the Mind I

Credit points: 2 Teacher/Coordinator: Professor Colin Sullivan Session: Semester 1,Semester 2 Classes: ~2 hours online lectures over 1 semester plus directed reading and independent study Assessment: 1xonline quiz (30%), 1xexam (70%) Campus: Camperdown/Darlington Mode of delivery: On-line
Aims: To understand the importance of psychological factors in sleep medicine; to examine the specific interaction between the physiological and psychic factors that produce some sleep disorders, using insomnia as an example; to understand the cognitive processes that occur in sleep. Content: Insomnia: The occurrence and origins of this disorder will be discussed in the context of psychological and behavioural problems. The occurrence, clinical presentation and treatment of insomnia. Dreaming & Perception in Sleep: Theories on the origins and function of dreams will be discussed along with methods for study of dreams. Psychophysiology of Dreams: The relationship to dreaming and biophysical state will be examined along with the effect on dreams of various substances such as alcohol and psychiatric disorders. Dreaming Disorders: Nightmares and other phenomenon that have a disturbing effect on patients will be discussed.
SLEE5012 Practicum I

Credit points: 5 Teacher/Coordinator: Professor Colin Sullivan Session: Semester 1,Semester 2 Classes: Self-directed learning and application of previous theory. Expected student effort 6 hours per week. Also, an optional 1x1week residential school consisting of a series of lectures and practical classes is offered. Prerequisites: SLEE5003 and SLEE5005 Assessment: presentation on a topic chosen by the student (50%), 1x1hr sleep stage scoring assignment (50%) Campus: Camperdown/Darlington Mode of delivery: Block Mode
The practicum component involves application of the theory presented during the previous two semesters work. A presentation will be recorded electronically by the student who is expected to use the knowledge gained to present a well structured, well referenced coherent presentation on a topic of their choice. A nocturnal recording, with the software required to analyse it will be provided. The student will score and comment on this study.
SLEE5013 Non-Respiratory Sleep Disorders

Credit points: 2 Teacher/Coordinator: Professor Colin Sullivan Session: Semester 1,Semester 2 Classes: ~3.5 hours online lectures over 1 semester plus directed reading and independent study Prerequisites: SLEE5003 Assessment: 1xonline quiz (30%), 1xexam (70%) Campus: Camperdown/Darlington Mode of delivery: On-line
Aims:To understand the range of parasomnias and their classification; to understand the way in which neurological disorders in a range of systems can influence sleep. Content: Parasomnias I: Parasomnias are disorders of arousal, partial arousal and sleep transition. This module will discuss arousal disorders and sleep-wake transition disorders, such as sleep walking and rhythmic movement disorder. Parasomnias II: This module continues the discussion of the range of parasomnias including those associated with REM sleep such as REM behaviour disorder and other parasomnias such as bruxism. Degenerative Disorders: This section discusses the sleep effects of degenerative diseases such as Parkinson's disease and dementia, which also relates to the REM sleep disorders introduced in the Parasomnias II module. Restless Legs Syndrome & Other Disorders: This module discusses the sleep disturbances that involve the control of movement during sleep and include abnormalities in the amount of movement, loss of control of movement and abnormal forms of movement.
SLEE5014 Sleep and Breathing II

Credit points: 4 Teacher/Coordinator: Professor Colin Sullivan Session: Semester 1,Semester 2 Classes: ~1.5 hours online lectures over 1 semester plus directed reading and independent study Prerequisites: SLEE5003 and SLEE5008 Assessment: 1xonline quiz (20%), 1x1500 word essay (40%), 1xexam (40%) Campus: Camperdown/Darlington Mode of delivery: On-line
Aims: To develop understanding of the clinical assessment and management of pathologies of ventilation during sleep; to understand the theory of the current methods of treatment of sleep apnoea-hypopnoea; to gain knowledge of developing therapies. Content: Clinical Aspects of OSA: The presentation and clinical assessment of OSA. Nocturnal Asthma: Introduction to the pathophysiology of asthma, clinical presentation and management in the context of sleep. Continuous Positive Airway Pressure: The theory and practice of CPAP in the treatment of OSA. Surgical Therapy: Early attempts at a surgical cure. Uvulopalatoplasty and the more modern elegant techniques such as mandibular distraction. Oral Devices: The range and uses of oral appliances for treatment of OSA. Medical Therapy: This module discusses the options such as treatment of obesity and nasal appliances that are used to treat OSA and hypopnoea. Cardiovascular Disease and OSA. The epidemiological and medical evidence for the links between OSA and cardiovascular disease. Bilevel Pressure Support & Automatic Devices. Sophisticated appliances for the treatment of OSA and central apnoeas such as Cheyne-Stokes ventilation.
SLEE5015 Neuropharmacology of Sleep II

Credit points: 2 Teacher/Coordinator: Professor Colin Sullivan Session: Semester 1,Semester 2 Classes: ~2.5 hours online lectures over 1 semester plus directed reading and independent study Prerequisites: SLEE5010 Assessment: 1xonline quiz (50%), 1xexam (50%) Campus: Camperdown/Darlington Mode of delivery: On-line
Aims: To understand the pharmacological basis of effects of different classes of drugs on sleep; to become familiar with drugs used therapeutically in various aspects in sleep medicine. Content: Drugs That Alter Sleep: This module introduces the types of prescription drugs that disturb sleep or waking function and may affect sleep disordered breathing. Hypnotics: This module looks at drugs with hypnotic-sedative effects, their effects on sleep and uses in sleep medicine. Stimulants: Drugs that increase arousal, motor activity and alertness will be examined in terms of their physiological action and uses in sleep medicine. Drugs of Addiction: A number of drugs of abuse and addiction, including nicotine and alcohol will be examined in relation to their effects on the sleep cycle and relevance to sleep medicine.
SLEE5016 Sleep and the Mind II

Credit points: 1 Teacher/Coordinator: Professor Colin Sullivan Session: Semester 1,Semester 2 Classes: ~2 hours online lectures over 1 semester plus directed reading and independent study Prerequisites: SLEE5011 Assessment: 1xonline quiz (40%), 1xexam (60%) Campus: Camperdown/Darlington Mode of delivery: On-line
Aims: To gain knowledge of the effects of psychiatric disorders on sleep and some appreciation of the management of such patients; to understand the concept of sleep hygiene and the importance of behavioural modification as therapy. Content: Psychiatric Disorders and Sleep: Anxiety disorders mood disorders & schizophrenia all have a significant impact upon sleep and are examined in the context of patient management. Behavioural Therapies and Sleep Hygiene: Behavioural modification is very important in the management of a range of sleep disorders and such treatments are examined in this module.
SLEE5017 Sleep and Body Function

Credit points: 2 Teacher/Coordinator: Professor Colin Sullivan Session: Semester 1,Semester 2 Classes: directed reading and independent study Assessment: 1xonline quiz (50%), 1xexam (50%) Campus: Camperdown/Darlington Mode of delivery: Block Mode
Aims: To understand the changes in function of other organ systems in relation to sleep; to understand the effect of sleep on other organ systems and particular the effect of sleep disorders on the function of the body generally; to understand the changes that occur in sleep when the body is challenged by other diseases. Content: Hypertension, Stroke and Cardiovascular Function: Sleep and the problems associated with it in relation to cardiovascular problems will be discussed in this module. In addition, the association with sleep-disordered breathing will be discussed. Disruption of Rhythm: Shift work, jet lag and sleep disruption lead to generalized physiological and immunological problems. Gastrointestinal Physiology: The alterations in autonomic function during sleep have effects on gastrointestinal motility and function. As well as the normal gastrointestinal function during sleep, pathological conditions such as gastrooesophageal reflux will be discussed. Immunological Responses: Sleep is affected by bacterial challenge and other alterations of immunological state. These considerations are examined.
SLEE5019 Sleep in Development (Child)

Credit points: 2 Teacher/Coordinator: Professor Colin Sullivan Session: Semester 1,Semester 2 Classes: ~2 hours online lectures over 1 semester plus directed reading and independent study Assessment: 1x2400word literature review (50%), 1xexam (50%) Campus: Camperdown/Darlington Mode of delivery: On-line
Aims: To understand sleep and sleep disorders during early development; to be introduced to paediatric sleep medicine and patient management. Content: Development of Respiratory Control: Respiratory control and its relationship to the sleep-wake cycle is not constant throughout life, but displays marked changes during development. These developmental stages are discussed from fetal biophysical states through to childhood are discussed in this module. Central Apnoea & OSA in Children: The occurrence and clinical significance of these conditions are examined. Paediatric Parasomnias: Parasomnias that are of interest in paediatrics are discussed, from night terrors to SIDS. Management of Paediatric Sleep Disorders: The diagnosis and treatment of sleep disorders in children.
SLEE5020 Sleep and Breathing III

Credit points: 2 Teacher/Coordinator: Professor Colin Sullivan Session: Semester 1,Semester 2 Classes: ~4.5 hours online lectures over 1 semester plus directed reading and independent study Prerequisites: SLEE5014 Assessment: 1xonline quiz (20%),1x1500word essay (30%), 1xexam (50%) Campus: Camperdown/Darlington Mode of delivery: On-line
Aims: To understand the impact of respiratory disorders and diseases on sleep and breathing; to understand the principles of clinical management of these patients in the context of sleep medicine. Content: chronic obstructive pulmonary disease (COPD); neuromuscular disorders; restrictive lung disease; cystic fibrosis.
SLEE5021 Neuropharmacology of Sleep III

Credit points: 2 Teacher/Coordinator: Professor Colin Sullivan Session: Semester 1,Semester 2 Classes: directed reading and independent study Prerequisites: SLEE5015 Assessment: 1xonline quiz (50%), 1xexam (50%) Campus: Camperdown/Darlington Mode of delivery: Normal (lecture/lab/tutorial) Day
Aims: To understand how knowledge of the neuropharmacology of a sleep disorder is gained and how this is used to develop therapeutic strategies; to gain an appreciation of the direction of current research into drug therapies for sleep disorders and the problems associated with this; to understand methods used to assess the efficacy of drugs and how to critically appraise trials of therapies generally. Content: Narcolepsy: This condition has been studied extensively in humans and animal models and the neuropharmacology is reasonably well understood. This module examines the study of this condition and drug therapies. Possible Drug Therapies for OSA: The pharmacology of systems involved in OSA is examined and ways in which these might be targeted by drug therapy and the problems that are encountered. Pharmacology and Chronobiology: Drugs that alter the circadian clock (chronotropes) are discussed and their efficacy in treating sleep disorders. Assessment of Drug Therapy: This module deals with the critical analysis of drug effect. The methods of assessment and the ways in which the data is presented are discussed.
SLEE5023 Sleep in Development (Adult)

Credit points: 2 Teacher/Coordinator: Professor Colin Sullivan Session: Semester 1,Semester 2 Classes: directed reading and independent study Assessment: 1x2400word literature review (50%), 1xexam (50%) Campus: Camperdown/Darlington Mode of delivery: Normal (lecture/lab/tutorial) Day
Aims: To understand sleep and sleep disorders throughout life; to understand issues specific to adult sleep medicine and patient management. Content: Cardiorespiratory Physiology Through the Life-Cycle: This module charts the development of the cardiorespiratory systems from adolescence to old age with reference to sleep disorders. Sleep in Pregnancy & Lactation: Sleep architecture is altered during these states and during pathological conditions such as preeclampsia. Studies of these aspects of the life cycle are reviewed. Management of Sleep Disorders: From OSA to geriatric sleep fragmentation, this module considers clinical presentation and management of different age-groups. Epidemiology of Sleep and Public Health: Sleep research over the last fifty years has indicated that disorders of sleep such as snoring are not just an annoyance, but have serious ramifications for public health. In addition, sleep monitoring can detect the early development of disorders and so can improve management in other areas of medicine. These issues are discussed.
SLEE5024 Practicum II

Credit points: 5 Teacher/Coordinator: Professor Colin Sullivan Session: Semester 1,Semester 2 Classes: Self-directed learning and application of previous theory. Expected student effort 6-8 hours per week. Also, an optional 1x1week residential school consisting of a series of lectures and practical classes is offered if not undertaken in SLEE5012. Prerequisites: SLEE5003 and SLEE5005 and SLEE5012 Assessment: 1xpresentation (50%), 2x1hr sleep study scoring sessions (50%) Campus: Camperdown/Darlington Mode of delivery: Block Mode
In this unit the theory presented during the previous four semesters work will be used in practice. Students will prepare and electronically record a presentation on a topic of their choice using the knowledge gained throughout the course. The student will also score and report several complex nocturnal sleep recording.
SLEE5025 Treatise

Credit points: 12 Teacher/Coordinator: Professor Colin Sullivan Session: Semester 1,Semester 2 Prohibitions: SLEE5027, SLEE5028 Assessment: 20,000-30,000 research treatise Campus: Camperdown/Darlington Mode of delivery: Normal (lecture/lab/tutorial) Day
Note: Department permission required for enrolment
Note: Students are required to seek permission from the course coordinator in order to enrol in this unit. If permission is given the coordinator emails the Postgraduate Student Administration Unit asking that the student be enrolled.
To meet the requirements of the master's degree, students need to complete either SLEE5025 Treatise (12CP) or both SLEE5027 Treatise A and SLEE5028 Treatise B (12 credit points in total). Candidates will be assisted in all aspects of study design, implementation, analysis and research writing.
SLEE5027 Treatise A

Credit points: 6 Teacher/Coordinator: Professor Colin Sullivan Session: S2 Late Int,Semester 1,Semester 2 Classes: online Prohibitions: SLEE5025 Assessment: 20,000-30,000 research treatise due after completion of 12 credit points Campus: Camperdown/Darlington Mode of delivery: On-line
Note: Department permission required for enrolment
Note: Students are required to seek permission from the course coordinator in order to enrol in this unit. If permission is given the coordinator emails the Postgraduate Student Administration Unit asking that the student be enrolled.
To meet the requirements of the master's degree, students need to complete both SLEE5027 Treatise A and SLEE5028 Treatise B (12 credit points in total) or SLEE5025 Treatise (12CP). Candidates will be assisted in all aspects of study design, implementation, analysis and research writing.
SLEE5028 Treatise B

Credit points: 6 Teacher/Coordinator: Professor Colin Sullivan Session: S2 Late Int,Semester 1,Semester 2 Classes: online Prohibitions: SLEE5025 Assessment: 20,000-30,000 research treatise due after completion of 12 credit points Campus: Camperdown/Darlington Mode of delivery: On-line
Note: Department permission required for enrolment
Note: Students are required to seek permission from the course coordinator in order to enrol in this unit. If permission is given the coordinator emails the Postgraduate Student Administration Unit asking that the student be enrolled.
To meet the requirements of the master's degree, students need to complete both Treatise A and Treatise B (12 credit points in total) or SLEE5025 Treatise (12CP). This unit requires completion of the research project commenced in Treatise A. Candidates will be assisted in all aspects of study design, implementation, analysis and research writing.