Biomedical Engineering 1A introduces students to the biomedical engineering discipline of study and profession. Initial lectures will introduce the various Biomedical Technologies in the global market, and currently under development, as well as the Biomedical Engineering Sector itself. It will address the question: 'what is biomedical engineering and what are the career opportunities?'. The healthcare sector will be outlined, including the roles of hospitals and clinics and how these are anticipated to evolve in the future. A virtual tour of a hospital with a focus on engineering-relevant areas will be provided. Students will be required to research and present a short overview of the background, capabilities, facilities, and specializations for a select hospital or clinic in the Sydney region. Biomed design projects will be set up to provide students the opportunity to get hands-on experience in 'lean start-up' teams. The semester-long projects will provide students with the opportunity to learn and practice how to effectively develop then propose innovative biomedical engineering solutions that address defined health needs and market opportunity. Succinct project reports and presentations with technical basis and specifications will be generated to be accessible to broad audiences. The projects will be presented by the teams at an innovation competition with industry guests at the end of semester.

This biomedical engineering core junior unit of study provides an introduction to the relatively recent, and rapidly growing, biotechnology industry, with a focus on the current key commercial applications. In the 1990s, the word 'biotech' entered our lexicon as a synonym for overnight investment wealth. The biotechnology acronym GM (genetically modified) also entered our lexicon in the 1990s. Biotechnology can be broadly defined as the commercial exploitation of biological processes for industrial and other purposes. A significant focus for commercial activities has been GM technology: GM microorganisms, plants, animals, and even humans (gene therapy). The 'biotech industry' arose rapidly in the late 20th century, and is now one of the largest industries in the world, and is one of the cornerstones of the global biomedical industry which comprises three main sectors: Medical Devices, Pharmaceuticals, and Biotechnology. Significant global commercial biotechnology activity concerns the manufacture of therapeutic compounds from GM microorganisms using bioreactors, for example insulin. Another significant sector is agricultural: 'agri-biotech' which concerns GM higher lifeforms (plants and animals) primarily for the food industry, and also other industries such as the energy industry (biofuels). The third sector concerns therapeutic GM of humans, known as 'gene-therapy'. Some other important biotechnologies will also be explored including monoclonal antibodies, genome sequencing and personalised medicine, and RNA-interference technology (RNAi).

The ability to design within the context of biomedical engineering requires cross-disciplinary knowledge and an appreciation and application of professional engineering standards and ethics. This unit provides students the opportunity to experience the design process and to develop good engineering skills. Students will build on skills and knowledge developed in prerequisite units and be introduced to standards and creative tools relevant to biomedical applications. The importance of standard engineering drawings in the communication and definition of parts and assemblies, the use of a CAD package to create them, and the importance and deeper understanding of standard components will be integral to the learning in this unit. Students will also learn and use the design process from initial idea to finished product, and practice various methods used to generate creative solutions.

This unit of study provides the underpinning knowledge needed in biomedical engineering designs. The anatomic and physiological functional knowledge gained in this subject will enhance prototype development of biomedical designs. Students should gain familiarity with anatomical and physiological terms and their meaning, understanding of the gross anatomy of the major systems in the human body and their importance in the design of biomedical devices and understanding of the major physiological principles which govern the operation of the human body.

AMME2960 Biomedical Engineering 2 is the third of the four Biomedical Engineering foundational units. The first (AMME1960 Biomedical Engineering 1A) introduces students to the discipline of biomedical engineering, covering the key concepts of biomedical technology, design, biomechanics, and the important systems of the human body from a biomedical engineering perspective. The second (AMME1961 Biomedical Engineering 1B) is an introduction to Biotechnology. The fourth (MECH2901 Anatomy and Physiology for Engineers) provides a hands-on anatomy and physiology study of the key systems of the human body from a biomedical engineering perspective and includes cadaver laboratories. This unit (AMME2960 Biomedical Engineering 2) is designed to provide students with the necessary tools for mathematically modelling and solving problems in engineering. Engineering methods will be considered for a range of canonical problems, including conduction heat transfer in one and two dimensions, vibration, stress and deflection analysis, convection and stability problems. The mathematical tools covered in the lectures include: deriving analytical solutions via separation of variables, Fourier series and Fourier transforms, Laplace transforms, scaling and solving numerically using finite differences, finite element and finite volume approaches. There is a strong emphasis in both the lectures and tutorials on applying these mathematical methods to real biomedical engineering problems involving electrical, mechanical, thermal and chemical mechanisms in the human body. Specific examples include heat regulation, vibrations in biological systems, and the analysis of physiological signals such as ECG and EEG.

The unit aims to teach the fundamentals of biomedical manufacturing processes, including traditional and advanced manufacturing technologies. This unit aims to develop the following attributes: to understand the fundamental principles of biomedical manufacturing approaches; to gain the ability to understand and select appropriate manufacturing processes and systems for biomedical applications; to develop ability to create innovative new manufacturing technologies for medical bionics and other applications in biomedical engineering; to develop ability to invent new manufacturing systems suitable for biomedical engineering implementation. At the end of this unit students will have a good understanding of the following: merits and advantages of individual manufacturing processes and systems used in the fabrication of medical devices and products that support human health and well-being; principles of developing new technologies for biomedical engineering applications; comprehensive applications and strategic selection of manufacturing processes and systems within the regulatory landscape of biomedical manufacturing. Unit content will include: Materials Processing: An introduction into the use of joining, moulding, and other manufacturing processes. Rapid Prototyping: An introduction into the most current prototyping methods currently in use. Manufacturing Processes: Common processes and their science (machining, moulding, sintering, materials processing, joining processes) and their relative merits and limitations.

This unit aims to give students an understanding of the Australian and International biomedical industry and in the development, manufacture and uses of biomedical engineering products in therapeutic, rehabilitation and clinical settings. Students will gain an understanding of the process of biomedical regulation in Australia and other major international markets as well as the entire process of creating a new biomedical engineering product, from design through to marketing and monitoring of the product. Students will design a biomedical device including the preparation of a detailed design brief. This will be done as a team project. Each team will work on a specific biomedical design project following formal design protocols, including design control, regulatory considerations, and commercialisation/IP considerations.

Students spend 6 months at an industrial placement working on a major engineering project relevant to their engineering stream. This is a 24 credit point unit, which may be undertaken as an alternative to BMET4111/4112 Thesis A and B, and two recommended electives. This unit of study gives students experience in carrying out a major project within an industrial environment, and in preparing and presenting detailed technical reports (both oral and written) on their work. The project is carried out under joint University/industry supervision, with the student essentially being engaged fulltime on the project at the industrial site.

The ability to plan, systematically conduct and report on a major project, involving both research and design, is an important skill for professional engineers. The final year thesis units (Thesis A and Thesis B) aim to provide students with the opportunity to carry out a defined piece of independent research and design that fosters the development of engineering skills. These skills include: the capacity to define a problem; carry out systematic research in exploring how it relates to existing knowledge; identifying the tools needed to address the problem; designing a solution, product or prototype; analysing the results obtained; and presenting the outcomes in a report that is clear, coherent and logically structured. The thesis is undertaken across two CONSECUTIVE semesters of enrollment, if not students will have to enroll in Thesis A again. Taken together, the thesis A covers initial research into the background of the problem being considered (formulated as a literature review), development of a detailed proposal incorporating project objectives, planning, and risk assessment, preliminary design, modelling and/or experimental work, followed by the detailed work in designing a solution, performing experiments, evaluating outcomes, analysing results, and writing up and presenting the outcomes. The final grade is based on the work done in both Honours Thesis A and B, and will be awarded upon successful completion Thesis B. While recognising that some projects can be interdisciplinary in nature, it is the normal expectation that the students would do the project in their chosen area of specialisation. For student who are completing a Major within their BE degree, the thesis topic must be within the area of the Major. The theses to be undertaken by students will very often be related to some aspect of a staff member's research interests. Some projects will be experimental in nature, others may involve computer-based simulation and analysis, feasibility studies or the design, construction and testing of equipment. All however will require students to undertake research and design relevant to the topic of their thesis. The direction of thesis work may be determined by the supervisor or be of an original nature, but in either case the student is responsible for the execution of the practical work and the general layout and content of the thesis itself. The thesis must be the student's individual work although it may be conducted as a component of a wider group project. Students undertaking research on this basis will need to take care in ensuring the quality of their own research and design work and their individual final thesis submission. The thesis will be judged on the extent and quality of the student's original work and particularly how critical, perceptive and constructive he or she has been in assessing his/her work and that of others. Students will also be required to present the results of their thesis to their peers and supervisors as part of a seminar program. Whilst thesis topics will be constrained by the available time and resources, the aim is to contribute to the creation of new engineering knowledge, techniques and/or solutions. Students should explore topics that arouse intellectual curiosity and represent an appropriate range and diversity of technical and conceptual research and design challenges.

The ability to plan, systematically conduct and report on a major project, involving both research and design, is an important skill for professional engineers. The final year thesis units (Thesis A and Thesis B) aim to provide students with the opportunity to carry out a defined piece of independent research and design that fosters the development of engineering skills. These skills include: the capacity to define a problem; carry out systematic research in exploring how it relates to existing knowledge; identifying the tools needed to address the problem; designing a solution, product or prototype; analysing the results obtained; and presenting the outcomes in a report that is clear, coherent and logically structured. The thesis is undertaken across two CONSECUTIVE semesters of enrollment, if not students will have to enroll in Thesis A again. Taken together, the thesis A covers initial research into the background of the problem being considered (formulated as a literature review), development of a detailed proposal incorporating project objectives, planning, and risk assessment, preliminary design, modelling and/or experimental work, followed by the detailed work in designing a solution, performing experiments, evaluating outcomes, analysing results, and writing up and presenting the outcomes. The final grade is based on the work done in both Honours Thesis A and B, and will be awarded upon successful completion Thesis B. While recognising that some projects can be interdisciplinary in nature, it is the normal expectation that the students would do the project in their chosen area of specialisation. For student who are completing a Major within their BE degree, the thesis topic must be within the area of the Major. The theses to be undertaken by students will very often be related to some aspect of a staff member's research interests. Some projects will be experimental in nature, others may involve computer-based simulation and analysis, feasibility studies or the design, construction and testing of equipment. All however will require students to undertake research and design relevant to the topic of their thesis. The direction of thesis work may be determined by the supervisor or be of an original nature, but in either case the student is responsible for the execution of the practical work and the general layout and content of the thesis itself. The thesis must be the student's individual work although it may be conducted as a component of a wider group project. Students undertaking research on this basis will need to take care in ensuring the quality of their own research and design work and their individual final thesis submission. The thesis will be judged on the extent and quality of the student's original work and particularly how critical, perceptive and constructive he or she has been in assessing his/her work and that of others. Students will also be required to present the results of their thesis to their peers and supervisors as part of a seminar program. Whilst thesis topics will be constrained by the available time and resources, the aim is to contribute to the creation of new engineering knowledge, techniques and/or solutions. Students should explore topics that arouse intellectual curiosity and represent an appropriate range and diversity of technical and conceptual research and design challenges.

This course is divided into two parts: biomechanics and biomaterials: Biomechanics is the study of the body from the point of view of it being an engineering structure. There are many aspects to this since the human body contains soft tissues, hard tissues (skeletal system), and articulating joints. We will begin with a general introduction to biomechanics, modelling the human body from the macroscopic level to the microscopic level. We will then study soft tissue mechanics, with respect to both non-linear and viscoelastic descriptions, with a significant focus on the mathematical methods used in relation to the mechanics of the system. We will then look at specific aspects of biomechanics: muscle mechanics, joint mechanics, kinematics and dynamics of human gait (gait analysis), biomechanics of cells, physiological fluid flow, biomechanics of injury, functional and mechanical response of tissues to mechanical loading. Biomaterials This course will involve the study of biomaterials from two perspectives: firstly, the response of the body towards the biomaterial - an immune response and foreign body reaction; secondly, the response of the biomaterial to the body - corrosion, biodegradation, and mechanical failure. Our study will begin with the response of the body towards the biomaterial. We will begin by looking at the immune system itself and then move on to look at the normal inflammatory response. We will then study in detail the foreign body reaction caused by biomaterials. The final part of this section is the study of protein adsorption onto biomaterials, with a strong focus on the Vroman effect. Then we will move onto the response of the biomaterial to the body. We will begin by a review of biomaterials, their applications, and compositions, and mechanical properties. We will then look at key problems such as corrosion, stress shielding, static fatigue, and mechanical failure. Finally, we will take a practical look at the materials themselves. Beginning with metals, then polymers (thermoplastic, thermosetting, and biodegradable), and finally ceramics (bioinert, biodegradable, and bioactive).

With the severe worldwide shortage of donor organs and the ubiquitous problem of donor organ rejection, there is a strong need for developing technologies for engineering replacement organs and other body parts. Recent developments in engineering and the life sciences have begun to make this possible, and as a consequence, the very new and multidisciplinary field of tissue engineering has been making dramatic progress in the last few years. This unit will provide an introduction to the principles of tissue engineering, as well as an up to date overview of recent progress and future outlook in the field of tissue engineering. This unit assumes prior knowledge of cell biology and chemistry and builds on that foundation to elaborate on the important aspects of tissue engineering. The objectives are: To gain a basic understanding of the major areas of interest in tissue engineering; To learn to apply basic engineering principles to tissue engineering systems; To understand the promises and limitations of tissue engineering; To understand the advances and challenges of stem cell applications; Enable students to access web-based resources in tissue engineering; Enable students to develop basic skills in tissue engineering research.

This UoS will give students an understanding of CT/MRI based solid modelling, finite element methods, constitutive material models, design analysis and optimisation, experimental validation and their use in biomedical engineering. The students are expected to gain skills and experience with finite element software for the solution to sophisticated problems associated with biomedical engineering and experimentation techniques for the validation of these problems. The unit will take a holistic approach to the learning outcomes: an overview of typical biomedical design problems, an overview of finite element analysis software, a detailed look at finite element methods in biomedical applications, and a project-based learning approach to the development of a biomedical prosthesis. By the end of the unit, the students are expected to have familiarised themselves with design analysis, optimisation, and validation for biomedical engineering problems.

Product development in the biomedical area presents unique challenges that need to be addressed to efficiently satisfy strict regulatory requirements and to successfully advance products to approval for marketing. Biomedical engineers need a broad understanding of these challenges as the main components of product development are complex and interdependent. Development of good manufacturing and quality control processes, preclinical and clinical validation of product safety and efficacy, and regulatory filings, are each progressive and interdependent processes. This UoS will provide a broad understanding of regulatory requirements for biomedical product development, with particular emphasis on the dependence of each component on the development of processes and control systems that conform to Good Manufacturing Practice. This UoS assumes prior knowledge of cell biology and chemistry and builds on that foundation to elaborate on the important aspects of biomedical product development.

Students spend 6 months at an industrial placement working on a major engineering project relevant to their engineering stream. This is a 24 credit point unit, which may be undertaken as an alternative to ENGG5217 Practical Experience, BMET5020/5021 Capstone Project A and B and 12cp of specialist electives. This unit of study gives students experience in carrying out a major project within an industrial environment, and in preparing and presenting detailed technical reports (both oral and written) on their work. The project is carried out under joint University/industry supervision, with the student essentially being engaged full-time on the project at the industrial site.

The capstone project requires the student to plan and execute a substantial research-based project, using their technical and communication skills to design, evaluate, implement, analyse and theorise about developments that contribute to professional practice thus demonstrating the achievement of AQF Level 9. Students are required to carry out a defined piece of independent research in a setting and in a manner that fosters the development of engineering research skills. These skills include the capacity to define a research question, showing how it relates to existing knowledge, identifying the tools needed to investigate the question, carrying out the research in a systematic way, analysing the results obtained and presenting the outcomes in a report that is clear, coherent and logically structured. Capstone project is undertaken across two semesters of enrolment, in two successive Units of Study of 6 credits points each. Capstone Project A covers first steps of thesis research starting with development of research proposal. Project B covers the second of stage writing up and presenting the research results. Students are asked to write a thesis based on a research project, which is very often related to some aspect of a staff member's research interests. Some projects will be experimental in nature, others may involve computer-based simulation, feasibility studies or the design, construction and testing of equipment. Direction of thesis work may be determined by the supervisor, however the student is expected to make a significant contribution to the direction of the project, and the student is responsible for the execution of the practical work and the general layout and content of the thesis itself. The final thesis must be the student's individual work, although research is sometimes conducted in the framework of a group project shared with others. Students undertaking research on this basis will need to take care in ensuring the individual quality of their own research work and the final thesis submission. The thesis will be judged on the extent and quality of the student's original work and particularly how critical, perceptive and constructive he or she has been in assessing his/her work and that of others. Students will also be required to present the results of their findings to their peers and supervisors as part of a seminar program. A thesis at this level will represent a contribution to professional practice or research, however the timeframe available for the thesis also needs to be considered when developing project scopes. Indeed, a key aim of the thesis is to specify a research topic that arouses sufficient intellectual curiosity, and presents an appropriate range and diversity of technical and conceptual challenges, while remaining manageable and allowing achievable outcomes within the time and resources available. It is important that the topic be of sufficient scope and complexity to allow a student to learn their craft and demonstrate their research skills. Equally imperative is that the task not be so demanding as to elude completion. Finally the ability to plan such a project to achieve results within constraints and the identification of promising areas and approaches for future research is a key assessment criterion.

The capstone project requires the student to plan and execute a substantial research-based project, using their technical and communication skills to design, evaluate, implement, analyse and theorise about developments that contribute to professional practice thus demonstrating the achievement of AQF Level 9. Students are required to carry out a defined piece of independent research in a setting and in a manner that fosters the development of engineering research skills. These skills include the capacity to define a research question, showing how it relates to existing knowledge, identifying the tools needed to investigate the question, carrying out the research in a systematic way, analysing the results obtained and presenting the outcomes in a report that is clear, coherent and logically structured. Capstone project is undertaken across two semesters of enrolment, in two successive Units of Study of 6 credits points each. Capstone Project A covers first steps of thesis research starting with development of research proposal. Project B covers the second of stage writing up and presenting the research results. Students are asked to write a thesis based on a research project, which is very often related to some aspect of a staff member's research interests. Some projects will be experimental in nature, others may involve computer-based simulation, feasibility studies or the design, construction and testing of equipment. Direction of thesis work may be determined by the supervisor, however the student is expected to make a significant contribution to the direction of the project, and the student is responsible for the execution of the practical work and the general layout and content of the thesis itself. The final thesis must be the student's individual work, although research is sometimes conducted in the framework of a group project shared with others. Students undertaking research on this basis will need to take care in ensuring the individual quality of their own research work and the final thesis submission. The thesis will be judged on the extent and quality of the student's original work and particularly how critical, perceptive and constructive he or she has been in assessing his/her work and that of others. Students will also be required to present the results of their findings to their peers and supervisors as part of a seminar program. A thesis at this level will represent a contribution to professional practice or research, however the timeframe available for the thesis also needs to considered when developing project scopes. Indeed, a key aim of the thesis is to specify a research topic that arouses sufficient intellectual curiosity, and presents an appropriate range and diversity of technical and conceptual challenges, while remaining manageable and allowing achievable outcomes within the time and resources available. It is important that the topic be of sufficient scope and complexity to allow a student to learn their craft and demonstrate their research skills. Equally imperative is that the task not be so demanding as to elude completion. Finally the ability to plan such a project to achieve results within constraints and the identification of promising areas and approaches for future research is a key assessment criterion.

The capstone project requires the student to plan and execute a substantial research-based project, using their technical and communication skills to design, evaluate, implement, analyse and theorise about developments that contribute to professional practice thus demonstrating the achievement of AQF Level 9. Students are required to carry out a defined piece of independent research in a setting and in a manner that fosters the development of engineering research skills. These skills include the capacity to define a research question, showing how it relates to existing knowledge, identifying the tools needed to investigate the question, carrying out the research in a systematic way, analysing the results obtained and presenting the outcomes in a report that is clear, coherent and logically structured. Capstone project is undertaken across two semesters of enrolment, in two successive Units of Study of 6 credits points each. Capstone Project A covers first steps of thesis research starting with development of research proposal. Project B covers the second of stage writing up and presenting the research results. Students are asked to write a thesis based on a research project, which is very often related to some aspect of a staff member's research interests. Some projects will be experimental in nature, others may involve computer-based simulation, feasibility studies or the design, construction and testing of equipment. Direction of thesis work may be determined by the supervisor, however the student is expected to make a significant contribution to the direction of the project, and the student is responsible for the execution of the practical work and the general layout and content of the thesis itself. The final thesis must be the student's individual work, although research is sometimes conducted in the framework of a group project shared with others. Students undertaking research on this basis will need to take care in ensuring the individual quality of their own research work and the final thesis submission. The thesis will be judged on the extent and quality of the student's original work and particularly how critical, perceptive and constructive he or she has been in assessing his/her work and that of others. Students will also be required to present the results of their findings to their peers and supervisors as part of a seminar program. A thesis at this level will represent a contribution to professional practice or research, however the timeframe available for the thesis also needs to considered when developing project scopes. Indeed, a key aim of the thesis is to specify a research topic that arouses sufficient intellectual curiosity, and presents an appropriate range and diversity of technical and conceptual challenges, while remaining manageable and allowing achievable outcomes within the time and resources available. It is important that the topic be of sufficient scope and complexity to allow a student to learn their craft and demonstrate their research skills. Equally imperative is that the task not be so demanding as to elude completion. Finally the ability to plan such a project to achieve results within constraints and the identification of promising areas and approaches for future research is a key assessment criterion.

To complete a substantial research project and successfully analyse a problem, devise appropriate experiments, analyse the results and produce a well-argued, in-depth thesis. The final research project should be completed and reported at a level which meets AQF level 9 outcomes and has original components as would be expected in MPhil.

To complete a substantial research project and successfully analyse a problem, devise appropriate experiments, analyse the results and produce a well-argued, in-depth thesis. The final research project should be completed and reported at a level which meets AQF level 9 outcomes and has original components as would be expected in MPhil.

The aims and objectives of the UoS are: 1. To introduce the student to the details and practice of orthopaedic engineering; 2. To give students an overview of the diverse knowledge necessary for the design and evaluation of implants used in orthopaedic surgery; 3. To enable students to learn the language and concepts necessary for interaction with orthopaedic surgeons and the orthopaedic implant industry; 4. To introduce the student to the details and practice of other engineering applications in surgery, particularly in the cardiovascular realm.

The application of science and technology at the nanoscale for biomedical problems promises to revolutionise medicine. Recent years have witnessed unprecedented advances in the diagnosis and treatment of diseases by applying nanotechnology to medicine. This course focuses on explaining the fundamentals of nanomedicine, and highlighting the special properties and application of nanomaterials in medicine. This course also reviews the most significant biomedical applications of nanomaterials including the recent breakthroughs in drug delivery, medical imaging, gene therapy, biosensors and cancer treatment.

Nanotechnology in Biomedical Engineering will have a broad nanotechnology focus and a particular focus on the biophysics and electrical aspects of nanotechnology, as it relates to nanobiosensors and nanobioelectronics which represents a rapidly growing field in Biomedical Engineering that combines nanotechnology, electronics and biology with promising applications in bionics and biosensors. Nanodimensionality and biomimetics holds the potential for significant improvements in the sensitivity and biocompatibility and thereby open up new routes in clinical diagnostics, personalized health monitoring and therapeutic biomedical devices.

Mechanobiology has emerged as a new field of science that integrates biology and engineering and is now considered to have significant influence on the development of technologies for regenerative medicine and tissue engineering. It is well known that tissues and cells are sensitive to their mechanical environment and changes to this environment can affect the physiological and pathophysiological processes. Understanding the mechanisms by which biological cells sense and respond to mechanical signals can lead to the development of novel treatments and therapies for a variety of diseases.

Supply of medical devices, diagnostics and related therapeutic products is regulated in most jurisdictions, with sophisticated and complex regulatory regimes in all large economies. These regulations are applied both to manufacturers and designers and to biomedical engineers undertaking device custom manufacture or maintenance in clinical environments. This UoS will explore the different regulatory frameworks in the 'Global Harmonisation Task Force' group of jurisdictions (US, EU, Canada, Japan, Australia), as well as emerging regulatory practices in Asia and South America. Emphasis will be on the commonality of the underlying technical standards and the importance of sophisticated risk management approaches to compliance.

The field of 'bionics' is one of the primary embodiments of biomedical engineering. In the context of this unit, bionics is defined as a collection of therapeutic devices implanted into the body to restore or enhance functions lost through disease, developmental anomaly, or injury. Most typically, bionic devices intervene with the nervous system and aim to control neural activity through the delivery of electrical impulses. An example of this is a cochlear implant which delivers electrical impulses to physiologically excite surviving neurons of the auditory system, providing the capacity to elicit the psychological perception of sound. This unit primarily focuses upon the replacement of human senses, the nature and transduction of signals acquired, and how these ultimately effect neural activity.