Biology is an immensely diverse science. Biologists study life at all levels, from the fundamental building blocks (genes, proteins) to whole ecosystems in which myriads of species interact. Evolution is the unifying concept that runs through the life sciences, from the origin and diversification of life to understanding behaviour, to dealing with disease. Evolution through natural selection is the framework in biology in which specific details make sense. This unit explores how new species continue to arise while others go extinct and discusses the role of mutations as the raw material on which selection acts. It explains how information is transferred between generations through DNA, RNA and proteins, transformations which affect all aspects of biological form and function. Science builds and organises knowledge of life and evolution in the form of testable hypotheses. You will participate in inquiry-led practical classes investigating single-celled organisms and the diversity of form and function in plants and animals. By doing this unit of study, you will develop the ability to examine novel biological systems and understand the complex processes that have shaped those systems.

Biology is an immensely diverse science. Biologists study life at all levels, from the fundamental building blocks (genes, proteins) to whole ecosystems in which myriads of species interact. Evolution is the unifying concept that runs through the life sciences, from the origin and diversification of life to understanding behaviour, to dealing with disease. Evolution through natural selection is the framework in biology in which specific details make sense. This unit explores how new species continue to arise while others go extinct and discusses the role of mutations as the raw material on which selection acts. It explains how information is transferred between generations through DNA, RNA and proteins, transformations which affect all aspects of biological form and function. Science builds and organises knowledge of life and evolution in the form of testable hypotheses. You will participate in inquiry-led practical classes investigating single-celled organisms and the diversity of form and function in plants and animals.
Life and Evolution (Advanced) has the same overall structure as BIOL1006 but material is discussed in greater detail and at a more advanced level. Students enrolled in BIOL1906 participate in a research project with a focus on developing skills in critical evaluation, experimental design, data analysis and communication.

Biology is an immensely diverse science. Biologists study life at all levels, from the fundamental building blocks (genes, and proteins) to whole ecosystems in which myriad species interact. Evolution is the unifying concept that runs through the life sciences, from the origin and diversification of life to understanding behaviour, to dealing with disease. Evolution through natural selection is the framework in biology in which specific details make sense. Science builds and organises knowledge of life and evolution in the form of testable hypotheses. The practical work syllabus for BIOL1996 is different from that of BIOL1906 (Advanced) and consists of a special project-based laboratory.

Paradigm shifts in biology have changed the emphasis from single biomolecule studies to complex systems of biomolecules, cells and their interrelationships in ecosystems of life. Such an integrated understanding of cells, biomolecules and ecosystems is key to innovations in biology. Life relies on organisation, communication, responsiveness and regulation at every level. Understanding biological mechanisms, improving human health and addressing the impact of human activity are the great challenges of the 21st century. This unit will investigate life at levels ranging from cells, and biomolecule ecosystems, through to complex natural and human ecosystems. You will explore the importance of homeostasis in health and the triggers that lead to disease and death. You will learn the methods of cellular, biomolecular, microbial and ecological investigation that allow us to understand life and discover how expanding tools have improved our capacity to manage and intervene in ecosystems for our own health and organisms in the environment that surround and support us . You will participate in inquiry-led practicals that reinforce the concepts in the unit. By doing this unit you will develop knowledge and skills that will enable you to play a role in finding global solutions that will impact our lives.

Paradigm shifts in biology have changed the emphasis from single biomolecule studies to complex systems of biomolecules, cells and their interrelationships in ecosystems of life. Such an integrated understanding of cells, biomolecules and ecosystems is key to innovations in biology. Life relies on organisation, communication, responsiveness and regulation at every level. Understanding biological mechanisms, improving human health and addressing the impact of human activity are the great challenges of the 21st century. This unit will investigate life at levels ranging from cells, and biomolecule ecosystems, through to complex natural and human ecosystems. You will explore the importance of homeostasis in health and the triggers that lead to disease and death. You will learn the methods of cellular, biomolecular, microbial and ecological investigation that allow us to understand life and discover how expanding tools have improved our capacity to manage and intervene in ecosystems for our own health and organisms in the environment that surround and support us . This unit of study has the same overall structure as BIOL1007 but material is discussed in greater detail and at a more advanced level. The content and nature of these components may vary from year to year.

Paradigm shifts in biology have changed the emphasis from single biomolecule studies to complex systems of biomolecules, cells and their interrelationships in ecosystems of life. Such an integrated understanding of cells, biomolecules and ecosystems is key to innovations in biology. Life relies on organisation, communication, responsiveness and regulation at every level. Understanding biological mechanisms, improving human health and addressing the impact of human activity are the great challenges of the 21st century. This unit will investigate life at levels ranging from cells, and biomolecule ecosystems, through to complex natural and human ecosystems. You will explore the importance of homeostasis in health and the triggers that lead to disease and death. You will learn the methods of cellular, biomolecular, microbial and ecological investigation that allow us to understand life and intervene in ecosystems to improve health. The same theory will be covered as in the advanced stream but in this Special Studies Unit, the practical component is a research project. The research will be either a synthetic biology project investigating genetically engineered organisms or organismal/ecosystems biology. Students will have the opportunity to develop higher level generic skills in computing, communication, critical analysis, problem solving, data analysis and experimental design.

Without cells, life as we know it would not exist. These dynamic assemblies, packed with biological molecules are constantly in action. But how do cells work? Why is the food that you eat so important for cellular function? How is information transmitted from generation to generation? And, what happens as a result of disease or genetic mutation? In this unit of study you will learn how cells work at the molecular level, with an emphasis on human biochemistry and molecular biology. We will focus initially on cellular metabolism and how cells extract and store energy from fuels like fats and carbohydrates, how the use of fuels is modulated in response to exercise, starvation and disease, and how other key metabolites are processed. Then we will explore how genetic information is regulated in eukaryotes, including replication, transcription and translation, and molecular aspects of the cell cycle, mitosis and meiosis. Our practicals, along with other guided and online learning sessions will introduce you to widely applied and cutting edge tools that are essential for modern biochemistry and molecular biology. By the end of this unit you will be equipped with foundational skills and knowledge to support your studies in the life and medical sciences.

Without cells, life as we know it would not exist. These dynamic assemblies, packed with biological molecules are constantly in action. But how do cells work? Why is the food that you eat so important for cellular function? How is information transmitted from generation to generation? And, what happens as a result of disease or genetic mutation? In this unit of study you will learn how cells work at the molecular level, with an emphasis on human biochemistry and molecular biology. We will focus initially on cellular metabolism and how cells extract and store energy from fuels like fats and carbohydrates, how the use of fuels is modulated in response to exercise, starvation and disease, and how other key metabolites are processed. Then we will explore how genetic information is regulated in eukaryotes, including replication, transcription and translation, and molecular aspects of the cell cycle, mitosis and meiosis. The advanced laboratory component will provide students with an authentic research laboratory experience while in the theory component, current research topics will be presented in a problem-based format through dedicated advanced tutorial sessions. This material will be assessed by creative student-centered activities supported by eLearning platforms.

A single human cell contains billions of protein molecules that are constantly in motion. Why so many? What are they doing? And, how are they doing it? In simple terms, proteins define the function of and drive almost every process within cells. In this unit of study you will learn about the biochemistry of proteins in their natural environment - within cells - with a focus on eukaryotes including plant and other cell types. You will discover the dynamic interplay within and between proteins and other cellular components and how the physical properties of proteins dictate function. You will discover how proteins are compartmentalized, modified, folded, transported in and between cells, the mechanisms by which proteins regulate biological activities, interact and transport molecules across membranes, and how mutations in proteins can lead to pathological consequences. Our practicals, other guided and online learning sessions will introduce you to a wide range of currently utilised techniques for protein biochemistry ranging from protein visualization, quantification, purification and enzymatic activity, to in silico studies and cellular targeting experiments. By the end of this unit you will be equipped with foundational skills and knowledge to support your studies in the cellular and molecular biosciences.

A single human cell contains billions of protein molecules that are constantly in motion. Why so many? What are they doing? And, how are they doing it? In simple terms, proteins define the function of and drive almost every process within cells. In this unit of study you will learn about the biochemistry of proteins in their natural environment - within cells - with a focus on eukaryotes including plant and other cell types. You will discover the dynamic interplay within and between proteins and other cellular components and how the physical properties of proteins dictate function. You will discover how proteins are compartmentalized, modified, folded, transported in and between cells, the mechanisms by which proteins regulate biological activities, interact and transport molecules across membranes, and how mutations in proteins can lead to pathological consequences. There will be a research-focused approach to the advanced practical component, including real and virtual extensions to key experiments. This approach will continue in the lecture series with several unique advanced lectures covering current research topics. You will further investigate a selected area of interest from these topics using original source material and present your findings through an oral presentation in dedicated advanced tutorials.

The era of genomics has revolutionised our approach to biology. Recent breakthroughs in genetics and genomic technologies have led to improvements in human and animal health, in breeding and selection of economically important organisms and in the curation and care of wild species and complex ecosystems. In this unit, students will investigate/describe ways in which modern biology uses genetics and genomics to study life, from the unicellular through to complex multicellular organisms and their interactions in communities and ecosystems. This unit includes a solid foundation in classical Mendelian genetics and its extensions into quantitative and population genetics. It also examines how our ability to sequence whole genomes has changed our capacities and our understanding of biology. Links between DNA, phenotype and the performance of organisms and ecosystems will be highlighted. The unit will examine the profound insights that modern molecular techniques have enabled in the fields of developmental biology, gene regulation, population genetics and molecular evolution.

The era of genomics has revolutionised our approach to biology. Recent breakthroughs in genetics and genomic technologies have led to improvements in human and animal health, in breeding and selection of economically important organisms and in the curation and care of wild species and complex ecosystems. In this unit, students will investigate/describe ways in which modern biology uses genetics and genomics to study life, from the unicellular through to complex multicellular organisms and their interactions in communities and ecosystems. This unit includes a solid foundation in classical Mendelian genetics and its extensions into quantitative and population genetics. It also examines how our ability to sequence whole genomes has changed our capacities and our understanding of biology. Links between DNA, phenotype and the performance of organisms and ecosystems will be highlighted. The unit will examine the profound insights that modern molecular techniques have enabled in the fields of developmental biology, gene regulation, population genetics and molecular evolution. The Advanced mode of Genetics and Genomics will provide you with challenge and a higher level of academic rigour. You will have the opportunity to plan and carry out a project that will develop your skills in contemporary genetics/molecular biology techniques and will provide you with a greater depth of disciplinary understanding. The Advanced mode will culminate in a written report and in an oral presentation where you will discuss a recent breakthrough that has been enabled by the use of modern genetics and genomics technologies. This is a unit for anyone wanting to better understand the how genetics has shaped the earth and how it will shape the future.

This unit of study is designed to provide a comprehensive coverage of the activity of genes in living organisms, with a focus on eukaryotic and particularly human systems. The lecture component covers the arrangement and structure of genes, how genes are expressed, promoter activity and enhancer action. This leads into discussions on the biochemical basis of differentiation of eukaryotic cells, the molecular basis of imprinting, epigenetics, and the role of RNA in gene expression. Additionally, the course discusses the effects of damage to the genome and mechanisms of DNA repair. The modern techniques for manipulating and analysing macromolecules such as DNA and proteins and their relevance to medical and biotechnological applications are discussed. Techniques such as the generation of gene knockout and transgenic mice are discussed as well as genomic methods of analysing gene expression patterns. Particular emphasis is placed on how modern molecular biology and biochemical methods have led to our current understanding of the structure and functions of genes within the human genome. The practical course is designed to complement the lecture course and will provide students with experience in a wide range of techniques used in molecular biology laboratories.

This unit of study is designed to provide a comprehensive coverage of the activity of genes in living organisms, with a focus on eukaryotic and particularly human systems. The lecture component covers the arrangement and structure of genes, how genes are expressed, promoter activity and enhancer action. This leads into discussions on the biochemical basis of differentiation of eukaryotic cells, the molecular basis of imprinting, epigenetics, and the role of RNA in gene expression. Additionally, the course discusses the effects of damage to the genome and mechanisms of DNA repair. The modern techniques for manipulating and analysing macromolecules such as DNA and proteins and their relevance to medical and biotechnological applications are discussed. Techniques such as the generation of gene knockout and transgenic mice are discussed as well as genomic methods of analysing gene expression patterns. Particular emphasis is placed on how modern molecular biology and biochemical methods have led to our current understanding of the structure and functions of genes within the human genome. The practical course is designed to complement the lecture course and will provide students with experience in a wide range of techniques used in molecular biology laboratories.
The lecture component of this unit of study is the same as BCHM3071. Qualified students will attend seminars/practical classes in which more sophisticated topics in gene expression and manipulation will be covered.

This unit of study will explore the responses of cells to changes in their environment in both health and disease. The lecture course consists of four integrated modules. The first will provide an overview of the role of signalling mechanisms in the control of human cell biology and then focus on cell surface receptors and the downstream signal transduction events that they initiate. The second will examine how cells detect and respond to pathogenic molecular patterns displayed by infectious agents and injured cells by discussing the roles of relevant cell surface receptors, cytokines and signal transduction pathways. The third and fourth will focus on the life, death and differentiation of human cells in response to intra-cellular and extra-cellular signals by discussing the eukaryotic cell cycle under normal and pathological circumstances and programmed cell death in response to abnormal extra-cellular and intra-cellular signals. In all modules emphasis will be placed on the molecular processes involved in human cell biology, how modern molecular and cell biology methods have led to our current understanding of them and the implications of them for pathologies such as cancer. The practical component is designed to complement the lecture course, providing students with experience in a wide range of techniques used in modern molecular cell biology.

This unit of study will explore the responses of cells to changes in their environment in both health and disease. The lecture course consists of four integrated modules. The first will provide an overview of the role of signalling mechanisms in the control of human cell biology and then focus on cell surface receptors and the downstream signal transduction events that they initiate. The second will examine how cells detect and respond to pathogenic molecular patterns displayed by infectious agents and injured cells by discussing the roles of relevant cell surface receptors, cytokines and signal transduction pathways. The third and fourth will focus on the life, death and differentiation of human cells in response to intra-cellular and extra-cellular signals by discussing the eukaryotic cell cycle under normal and pathological circumstances and programmed cell death in response to abnormal extra-cellular and intra-cellular signals. In all modules emphasis will be placed on the molecular processes involved in human cell biology, how modern molecular and cell biology methods have led to our current understanding of them and the implications of them for pathologies such as cancer. The practical component is designed to complement the lecture course, providing students with experience in a wide range of techniques used in modern molecular cell biology.
The lecture component of this unit of study is the same as BCHM3072. Qualified students will attend seminars/practical classes in which more sophisticated topics in modern molecular cell biology will be covered.

A unit of study with lectures, practicals and tutorials on the application of recombinant DNA technology and the genetic manipulation of prokaryotic and eukaryotic organisms. Lectures cover the applications of molecular genetics in biotechnology and consider the regulation, impact and implications of genetic engineering and genomics. Topics include biological sequence data and databases, comparative genomics, the cloning and expression of foreign genes in bacteria, yeast, animal and plant cells, novel human and animal therapeutics and vaccines, new diagnostic techniques for human and veterinary disease, and the genetic engineering of animals and plants. Practical work may include nucleic acid isolation and manipulation, gene cloning and PCR amplification, DNA sequencing and bioinformatics, immunological detection of proteins, and the genetic transformation and assay of plants.

Qualified students will participate in alternative components of BIOL3018 Gene Technology and Genomics. The content and nature of these components may vary from year to year.

Developmental genetics discusses major concepts and our current understanding of developmental biology with an emphasis on molecular genetics. The developmental genetics of animal and plant systems will be investigated, along with approaches used to determine gene function in relation to development of complex multicellular organisms. Topics include the features and resources for model organisms; the generation of mutants for forward and reverse genetics; the application of mutants to the study gene function and gene networks; spatial and temporal gene expression in pattern formation; quantitative trait loci analysis; utility of genome wide association studies; epigenetics in relation to inheritance; genome information in the study of human genetics. Reference will be made to the use of modern techniques in developmental biology such as transgenics, recombinant DNA technology, tissue-specific expression analysis. Various methods of genetic mapping will be covered. Practical work complements the theoretical aspects of the course and develops important skills in genetics.

Qualified students will participate in alternative components to BIOL3026 Developmental Genetics. The content and nature of these components may vary from year to year. Some assessment will be in an alternative format to components of BIOL3026.