This online unit that can be undertaken either face-to-face, fully online, or in intensive block mode, introduces the concept of clinical epidemiology and provides students with core skills in clinical epidemiology at an introductory level. The unit is aimed at clinician learners and as such some clinical experience is required. Topics covered include asking and answering clinical questions; basic and accessible literature searching techniques; study designs used in clinical epidemiological research; confounding and effect modification; sources of bias; interpretation of results including odds ratios, relative risks, confidence intervals and p values; applicability of results to individual patients; critical appraisal of clinical epidemiological research literature used to answer questions of therapy (RCTs and systematic reviews), harm, prognosis, diagnosis and screening; applicability of results to individual patients; and evidence-based use of health resources.

This online unit that can be undertaken either face-to-face, fully online, or in intensive block mode, introduces the concept of clinical epidemiology and provides students with core skills in clinical epidemiology at an introductory level. The unit is aimed at clinician learners and as such some clinical experience is required. Topics covered include asking and answering clinical questions; basic and accessible literature searching techniques; study designs used in clinical epidemiological research; confounding and effect modification; sources of bias; interpretation of results including odds ratios, relative risks, confidence intervals and p values; applicability of results to individual patients; critical appraisal of clinical epidemiological research literature used to answer questions of therapy (RCTs and systematic reviews), harm, prognosis, diagnosis and screening; applicability of results to individual patients; and evidence-based use of health resources.

This is the capstone unit of the Genomics and Precision Medicine Master's degree and it aims to develop the ethical and critical thinking needed to inform best clinical practice in Genomic Medicine. It is divided into two parts: an introduction to key ethical concepts and methods of ethical analysis relevant to health care practice and research, and an overview of evidence. Students will critically appraise the evidence base related to an area of practice in their workplace or a clinical guideline. This will require the development of a clinical question, a literature review, then an appraisal of the literature and application of evidence to individual patient care. Learning modules will include how to carry out a literature review, an example of how clinical practice and guidelines have changed based on changing evidence and review, and further refinement of clinical epidemiology and critical appraisal skills developed in CEPI5100 Introduction to Clinical Epidemiology.

Recent major advances in understanding of the human genome and the relationship between genetic variation and disease have changed clinical practice. This unit provides contemporary knowledge of genetic disease, diagnosis, genomic testing, prognosis, management, inheritance and impact across a range of chromosomal, single gene and heterogeneous genetic conditions. You will study common conditions, such as intellectual disability, inherited cancer, and paediatric and adult-onset disorders, as well as genomic mechanisms and genetic variations which lead to human disease. A case based approach will be used to develop skills in interpretation of clinical, family history and genomic test results to formulate an appropriate diagnosis and accurate genetic risk information. Ethical issues in genomic medicine will also be considered. Advances in treatments for genetic diseases will be explored, along with possible uses and limitations of new technologies, including genome editing approaches. The RACP Clinical Genetics Advanced Training Committee has approved this unit to fulfill the Genetics University Course Requirement for advanced training in Clinical Genetics. It is suitable for all practitioners who require a working knowledge of genomics in clinical practice.

Recent technological advances in genetics and genomics have had a significant impact on medical care. This unit provides an introduction to the detection of genetic variation in the context of human disease and an overview of bioinformatics techniques and approaches for the analysis of genomic and other omic data Technologies include types of deep resequencing including whole exome and whole genome sequencing the library preparation methods and sequencing chemistries and platforms Methodologies and applications to diseases discussed include detection of base substitutions and splicing variants copy number variants and other structural variants. An understanding of which methodologies to be used to detect different types of genetic variants will be developed Cases will be used to illustrate the importance of integrating phenotypic data genomic information and variant interpretation for accurate diagnosis You will discuss techniques to prioritise variant pathogenicity and the application of new technologies in gene editing as well as omic technologies including transcriptomics proteomics and metabolomics and their current and future application to medical care.

Major advances and mainstreaming in genomics are impacting all specialty areas of medicine, leading to new approaches in diagnosis and management across a large range of conditions. This unit provides contemporary knowledge of these advances in many key subspecialty areas such as neurology, nephrology, cardiology, ophthalmology, and paediatric genomics.
This unit is for the advanced level non-genetics professional, aimed at providing the skills and understanding to be able to implement genomics in their own field of medicine, and understand the latest trends and approaches to genomic medicine. Students will gain a sophisticated knowledge and understanding of the integration of genomic and disease-specific clinical knowledge for optimum management, in a multidisciplinary approach with genetic counselling, bioinformatics, and molecular genetics. Case based multidisciplinary approaches will be used to develop skills to analyse the genetic and genomic literature in the context of disease-specific features and the clinical situation, to provide the most appropriate and timely diagnostic and genetic risk information for patients and families.
System and disease-specific advances in management of genetic conditions will be a focus including use of precision pharmacological and genetic therapies. There will also be an emphasis on the counselling and ethical issues of genomics, with input from consumer groups, education, health policy, and indigenous genomics experts.

Advances in genomics are impacting on many aspects of the diagnosis and management of cancer. This unit provides understanding of molecular mechanisms of oncogenesis, with particular reference to familial cancer conditions. It provides contemporary knowledge of familial cancer syndromes including their characteristic patterns of presentation, epidemiology, underlying causative genetic pathology and preventative management approaches. Case - based approaches will be used for the development of in-depth knowledge of familial breast, ovarian, bowel and endocrine malignancies. Other familial cancer syndromes explored will include the neurofibromatoses, and conditions such as Li-Fraumeni and Von Hippel Lindau syndromes. Review of other genetic conditions in which cancer risk is increased will be undertaken. Ethical issues in cancer genomics will be considered as well as advances in precision medicine applicable to familial cancer.

This unit of study introduces the student to basic concepts behind diagnostic and screening tests, including: test accuracy, sources of bias in test evaluation, critical appraisal of test evaluation studies, application of test results to individual patients, place of tests in diagnostic pathways, impact of tests on patient outcomes, principles and use of evidence in population screening, overdiagnosis, systematic review of diagnostic tests and meta-analysis. After completing this unit of study, the student should have a comprehensive understanding of contemporary issues and the methodology underlying, diagnostic and screening test evaluation and application.

In this unit of study, the student will develop his/her own research proposal, to a standard suitable for a peer-reviewed granting body. Each section of a grant proposal (Abstract, Aims, Background, Significance, Methods) will be discussed, with the student presenting and refining the corresponding section of his/her own proposal in a synchronous online workshop setting. This will be complemented by online presentations from experienced researchers on the practical aspects of clinical research. Topics include: observational studies, randomised controlled trials, diagnostic test evaluation, qualitative studies, economic evaluation, and process evaluation. The unit will conclude with a one-day, face-to-face, mandatory workshop where students will learn about budgeting, qualitative research, strategies and grant administration, research ethics and peer review of research grants.

This unit of study will appeal to anyone wanting to write medical papers for conferences or journals, or to improve their paper writing skills. Students will work at their own pace through 9 modules covering research integrity, medical style, abstracts, presentations and posters, constructing a paper, data visualisation, manuscript submission, responding to reviewers' comments, post-publication research dissemination, and peer- reviewing a paper. This unit aims to teach students the principles of research integrity in writing for medical journals, typical issues they may face, and link to resources to help them maintain integrity through their publishing careers. It will guide them to reliable evidence-based resources to improve their conference abstract, presentation and poster design, and manuscript style and writing. Students will learn about reporting guidelines, common pitfalls in writing and presenting research, choosing a journal, keywords, improving tables and figures for manuscripts through open source software, copyright, writing cover letters and response letters to reviewers. Students will learn about measuring research impact and ways to improve research reach, dealing with the media and press releases, using social media in dissemination, digital archiving and basic skills needed to act as a peer-reviewer. This is an online unit, but those needing to study in block mode will do online study as well as a workshop.

Genomics has revolutionised medicine, providing information on a scale not previously available. Pathogen Genomics is part of this revolution and the applications of this technology have provided crucial information on pathogen discovery, new drug development, control of outbreaks, pandemics and antibiotic resistance. This unit of study will introduce students to analysis of bacterial and viral genomes and main applications of genomics for translational research, precision medicine and control of diseases with epidemic potential. Students will learn how DNA or RNA is sequenced in the laboratory and develop analytical skills in microbial genomics, using public databases and the University of Sydney's high performance computing cluster. A combination of lectures delivered by domain experts and interactive practicals will provide detailed understanding of the key concepts of genomics utilized in research and clinical practice.
Case studies will enable students to perform genomic analyses and apply the knowledge gained from the unit to examine virulence, drug resistance and evolution of pathogens. This unit will equip students with knowledge and skills increasingly important for careers in biomedical research and healthcare.

This unit introduces students to statistical methods relevant in medicine and health. Students will learn how to build datasets and basic data management procedures, summarise and visualise data, choose the correct statistical analysis, conduct this analysis using statistical software, interpret its results, and report statistical findings in a format suitable for inclusion in scientific publications. Students will also learn to consider the difference between statistical significance and practical importance, and how to determine the appropriate sample size when planning a research study. Specific analysis methods covered in this unit include: descriptive methods; hypothesis tests for one sample, paired samples and two independent groups for continuous and categorical data; correlation and linear regression; power and sample size estimation for simple studies. All these topics are introduced with an emphasis on practical application and interpretation and are supported using statistical software. The general principles developed in this unit can be easily extended to more advanced methods; students who wish to continue with their statistical learning after this unit are encouraged to take PUBH5217 Biostatistics: Statistical Modelling.

Many who come to assume leadership roles in health care often come to this responsibility without any exposure to leadership theory. Given this, HPOL5012 focuses on combining the development of an understanding of leadership theory with the personal development of students as health care leaders because ultimately leadership is about what you do, not what you know. Initially this is done by exploring the history of leadership theory and then taking this learning and applying it to the health care environment through a hierarchy that moves through ‘leading self’ then onto teams, organisations and ultimately society. The aim of this unit is to increase students' knowledge of leadership theory and their understanding of the connections between this theory and practice so as to assist their personal development as leaders in health care.

Almost all healthcare professionals are involved in education and training throughout their careers. This unit of study provides a practical introduction to the theory and practice of teaching and learning in the health environment. The unit will cover three main areas: planning for and facilitating learning in the clinical environment; assessing performance and providing constructive feedback; and fostering the development of students as professionals. Each of these areas will be underpinned by best evidence from clinical education research and will address current challenges and opportunities in the learning environment from the perspective of both educators and learners. Participants in the course will gain a framework they can use to support their teaching, and will develop a portfolio of evidence to support their professional development as clinician educators.

This unit will introduce students to the microskills and theories of counselling in a health setting. This unit of study includes online and/or in-person teaching sessions. These interactive sessions are compulsory. The interactive teaching sessions will extend the online content and provide skills development sessions. On completion of this unit, students will be able to: (i) Demonstrate the application of microskills to interpersonal communication, professional communication and in a counselling context; (ii) Apply basic counselling interventions in a health context; (iii) Critique the application of counselling and psychotherapy theories in health settings; (iv) Critique and discuss ethical issues in counselling; (v) Demonstrate the ability to develop a basic management plan for an individual based on best available research and clinical evidence; and (vi) Develop an understanding of the self in practise.

Candidates will work on an independent research project in an area of specific interest relevant to their master's degree. The project may take the form of analysis of an existing data set, a systematic or integrative review of the literature, a case series, survey or other project acceptable to the project supervisor. In some streams, projects may be available for students to select. It is essential, where there is the use of patient information or recruitment of patient study subjects, that appropriate ethics approval is gained from the governing body where the project will take place. The candidate will enter into a learning contract and will be guided through the steps required to plan and execute a substantial research project and prepare a scholarly work which may be a paper for publication. A candidate must enrol in a minimum of 12 credit points of project units of study in order to submit their final written work. Approval of the project and supervisor by the Program Director must be confirmed prior to commencing the project.

Candidates will work on an independent research project in an area of specific interest relevant to their master's degree. The project may take the form of analysis of an existing data set, a systematic or integrative review of the literature, a case series, survey or other project acceptable to the project supervisor. In some streams, projects may be available for students to select. It is essential, where there is the use of patient information or recruitment of patient study subjects, that appropriate ethics approval is gained from the governing body where the project will take place. The candidate will enter into a learning contract and will be guided through the steps required to plan and execute a substantial research project and prepare a scholarly work which may be a paper for publication. Where appropriate students will prepare a work suitable for publication. A candidate must enrol in a minimum of 12 credit points of project units of study in order to submit their final written work. Approval of the project and supervisor by the Program Director must be confirmed prior to commencing the project.

Candidates will work on an independent research project in an area of specific interest relevant to their master's degree. The project may take the form of analysis of an existing data set, a systematic or integrative review of the literature, a case series, survey or other project acceptable to the project supervisor. In some streams, projects may be available for students to select. It is essential where there is the use of patient information or recruitment of patient study subjects that appropriate ethics approval is gained from the governing body where the project will take place. The candidate will enter into a learning contract and will be guided through the steps required to plan and execute a substantial research project and prepare a scholarly work which may be a paper for publication. A candidate must enrol in a minimum of 12 credit points of project units of study in order to submit their final written work. Approval of the project and supervisor by the Program Director must be confirmed prior to commencing the project.